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Expanding the Biosynthetic Capabilities of Microbes Using Light

Researchers are continually looking for new ways to hack the cellular machinery of microbes like yeast and bacteria to make products that are useful for humans and society.

2 Feb 2026

Engineering Escherichia coli for Sustainable Biosynthesis of Lauryl Glucoside

By reconstructing a non-natural metabolic route in Escherichia coli, the researchers demonstrated that simple sugars can be biologically converted into lauryl glucoside through the coordinated production of its fatty alcohol precursor and a final glycosylation step.

21 Jan 2026

Engineered Human Skin Acts as a Living Biosensor for Inflammation

Implanted living skin-based biosensors offer a breakthrough in inflammation tracking, providing real-time biomarker monitoring without invasive procedures.

21 Jan 2026

New Enzyme and Bacteria Unlock Efficient Production of Healthy Sweetener

From saccharin in the 19th century to stevia and monk fruit in the 21st, researchers and the food industry have long sought a sweetener that delivers the taste of sugar without its drawbacks-excess calories, tooth decay, and heightened risk for obesity, insulin resistance, and diabetes.

14 Jan 2026

Giant Virus with A Massive Genome and Unusual Infection Strategy

Ushikuvirus, a newly identified giant virus, showcases unique cytopathic effects and structural features, enhancing knowledge of viral evolution and diversity.

14 Jan 2026

Turning Human Fat into Insulin-Producing Organoids That Reverse Diabetes

By preserving fat tissue architecture, researchers created organoids that restore insulin function, paving the way for advancements in diabetes treatment.

8 Jan 2026

Identifying Molecules That Activate and Inhibit Key Protein Function

Researchers at Northwestern University have discovered a concealed molecular "control switch" within a protein that plays a crucial role in the body's ability to perceive taste, regulate blood sugar, and protect the gut.

7 Jan 2026

Hidden Molecular "Control Switch" Uncovered Inside TRPM5 Protein

Northwestern University scientists have uncovered a hidden molecular "control switch" inside a protein that helps the body sense taste, control blood sugar and defend the gut.

6 Jan 2026

Study Reveals Glucose-Driven Mitochondrial Migration in Beta Cells

Unlike our organs, cell organelles such as mitochondria are not fixed in place, but when, where, how, and why organelles move remain unclear.

19 Dec 2025

Mitochondrial Supercomplex Protein COX7RP Extends Lifespan and Healthspan

As life expectancy continues to climb globally, the focus of many people has moved from longevity alone to living in good health.

11 Dec 2025

Cells Use Condensates to Save RNA Messages During Stress

All cells need to sense and respond to their environment, to know when to activate genes, build proteins, and carry out their basic functions.

4 Dec 2025

Transforming Stomach Cells into Insulin Factories for Diabetes Treatment

Type 1 diabetes is caused by an insufficient production of the hormone insulin by cells in the pancreas called beta cells and estimated to affect 9.5 million people worldwide.

7 Nov 2025

Study Unveils the Complete Biosynthetic Loop Regulating Tannin Production in Strawberries

Hydrolyzable tannins (HTs), including gallotannins and ellagitannins, are essential polyphenolic compounds that influence fruit taste, antioxidant capacity, and stress tolerance. Although condensed tannin biosynthesis has been well studied, the enzymatic processes governing HT formation remain unclear.

3 Nov 2025

Understanding Interplay of Physiological Processes as the Brain Shifts from Wakefulness to Sleep

Findings from Mass General Brigham investigators highlight the intricate interplay of diverse physiological processes as the brain shifts from wakefulness to sleep.

27 Oct 2025

Revolutionary Technique Produces Trillions of Healthy Endothelial Cells

Scientists have discovered a method to induce human endothelial cells from a small biopsy sample to multiply in the laboratory, producing more than enough cells to replace damaged blood vessels or nourish organs for transplantation, according to a preclinical study by Weill Cornell Medicine investigators.

15 Oct 2025

Acidic Tumor Environment Found to Rewire Cancer Cell Metabolism

Tumors are not a comfortable place to live: oxygen deficiency, nutrient scarcity, and the accumulation of sometimes harmful metabolic products constantly stress cancer cells.

10 Oct 2025

Intergenerational Transmission of Exercise Benefits Mediated by Sperm MicroRNAs

n a recent study published in Cell Metabolism, a collaborative research team led by Chen-Yu Zhang, Xi Chen, and Di-Jun Chen from Nanjing University, together with Tao Zhang from Nanjing Medical University, reported groundbreaking findings in their paper entitled "Paternal exercise confers endurance capacity to offspring through sperm microRNAs."

7 Oct 2025