Induced Pluripotent Stem Cells News and Research

RSS

Microgravity Drives the Metabolic Switch From Glycolysis to Oxidative Phosphorylation

Earth-based hiPSC models have transformed disease research but remain limited by cellular immaturity, a strong reliance on glycolysis rather than oxidative phosphorylation (OXPHOS), and incomplete tissue architecture.

4 Nov 2026

Genetic Clue to Autism's Fourfold Difference In Boys and Girls

Findings on MECP2 regulatory variants suggest genetic factors contribute to autism's male bias, enhancing understanding of the disorder's heritability.

22 Oct 2026

Cedars-Sinai Expands Stem Cell Research Aboard the Space Station

When NASA’s SpaceX CRS-35 mission docks with the International Space Station Oct. 15, it will deliver two experiments from the Cedars-Sinai Center for Space Medicine Research.

16 Oct 2026

Stem Cell Models Demonstrate Precise Cellular Nibbling of Pathological Fibrils

Researchers at the University of Oxford have uncovered a previously unrecognized protective role for microglia, the brain's resident immune cells, in Parkinson's disease.

8 Oct 2026

Engineered 3D miBrains Model Human Neurovascular Units and Pathology

Mount Sinai researchers have identified how APOE4, the strongest genetic risk factor for Alzheimer's disease, damages the brain's blood vessels and promotes the buildup of abnormal proteins linked to neurodegenerative disease.

26 Sep 2026

3D Stem-Cell miBrains Model Complex Neurovascular Pathology in Human Tissue

25 Sep 2026

Multi-Receptor Blocking Achieves Superior Antifibrotic Response Over Single-Receptor Inhibition

Three adenosine receptor subtypes that normally send different signals were found to converge on a common pathway that activates cardiac fibroblasts, the scar-forming cells in the heart. Blocking the receptors together produced a much stronger antifibrotic effect than blocking them one at a time.

25 Sep 2026

Bulky Molecular CRISPR Systems Barely Fit Inside Single Viral Vectors

The ability to precisely adjust the expression of genes inside the human body - ramping up protective ones and tamping down harmful ones - holds enormous potential for treating and preventing disease.

31 Aug 2026

Engineering Stem-Cell-Derived Immune Cells to Teach T Cells to Fight Cancer

The human body contains vast numbers of T cells capable of seeking out and eliminating malignancies if they were properly activated. Currently, a group from UC San Francisco has developed a technique to achieve this by merging laboratory-cultivated immune cells with samples from a person's malignancy.

26 Aug 2026

Kobe University Unveils Mass-Producible Off-the-Shelf Cancer Fighters

Off-the-shelf and mass-producible immune cells fight solid human tumors engrafted into mice. The Kobe University development is a significant contribution towards faster and cheaper cancer immunotherapy.

24 Jul 2026

New Method Derives Red Blood Cell-Like Cells From Canine iPSCs

Blood transfusions are crucial in human and veterinary medicine, yet human blood reserves are in constant need of donors while blood bank systems in veterinary care are nearly non-existent.

20 Jul 2026

New CRISPR Atlas Details How Every Gene Influences Stem Cells

A team led by bioengineers at the University of California San Diego has developed a genome-scale reference map that details how individual genes control the functions and identities of human stem cells.

14 Jul 2026

Live-Imaging Techniques Reveal How Stem Cells Collectively Suppress Tumors

It all starts with a single cell.

2 Jun 2026

New 3D-Printed Trays Help Produce Functioning Human Gut Organoids Twice as Fast

Thanks to special 3D-printed scaffolding trays designed by experts at Cincinnati Children's, researchers can now produce larger versions of functional human gut organoids twice as fast as previous methods-and these organoids grow their own nerve cells.

23 May 2026

Interactions Across the Genome Drive Neurodevelopmental Risks

People who have the same deletion of a section of chromosome 16 are susceptible to neurodevelopmental disorders; however, some may simply show moderate psychological symptoms like anxiety or depression, while others may have significant intellectual disability or developmental delay.

6 May 2026