Tissue Engineering News and Research

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Dramatic advances in the fields of biochemistry, cell and molecular biology, genetics, biomedical engineering and materials science have given rise to the remarkable new cross-disciplinary field of tissue engineering. Tissue engineering uses synthetic or naturally derived, engineered biomaterials to replace damaged or defective tissues, such as bone, skin, and even organs.

New 3D Cortical Tissue Models Incorporate Microglia to Bridge Preclinical Translation Gaps

28bio today announced CNS-3D Inflammatory Organoids, designed to evaluate efficacy of anti-inflammatory drugs by quantifying their ability to reduce inflammatory injury, preserve tissue health, and restore neuronal network activity.

20 May 2026

Cells Use a Timing Mechanism to Filter Persistent Physical Forces

Scientists have discovered how cells decide when to respond to physical forces, potentially opening new avenues for tackling diseases such as cancer and fibrosis.

30 Apr 2026

Force-Sensing Microgripper Enables Safe Handling of Cell Spheroids

In tissue engineering, the tiniest bit of improper force can harm a living culture. 3D clumps of cells - known as spheroids - can be used to model complex human tissues, because they can re-create specific cell-to-cell and cell-to-matrix interactions.

30 Apr 2026

New Strategy Enables 3D Tissue Engineering Without the Use of Scaffolds

Biological tissues have a remarkable ability to organize and change shape, driven by forces generated by their own cells. One of the major challenges in bioengineering is harnessing this natural behavior to design synthetic living materials capable of adopting predetermined shapes. However, precisely controlling how a tissue behaves and directing its internal forces to adopt the desired shape remains a significant scientific challenge.

17 Apr 2026

Regenerative Vascular Grafts Solve Key Shortage In Surgery

Engineered biotubes demonstrate strong mechanical performance and rapid tissue regeneration, offering a scalable solution to the vascular graft shortage.

2 Apr 2026

New Skin Atlas Reveals Cellular Diversity Across Body Sites

Mount Sinai researchers have published the first organ-wide human skin spatial atlas from across the body.

26 Mar 2026

Water Pressure Mechanism Enables Rapid Cancer Cell Migration

Cancer is one of the leading causes of death worldwide, marked by the uncontrolled growth of abnormal cells.

9 Feb 2026

Microfluidic Technology Creates Realistic 3D Cell Environments for Research

Most cells in the human body exist in complex three-dimensional environments, yet they are still commonly studied on flat plastic dishes.

30 Jan 2026

Bioengineered Lymphatic Tissue Shows Promise in Treating Secondary Lymphedema

The rising incidence of cancer worldwide has led to an increasing number of surgeries that involve the removal of lymph nodes.

27 Jan 2026

Engineered Human Skin Acts as a Living Biosensor for Inflammation

Implanted living skin-based biosensors offer a breakthrough in inflammation tracking, providing real-time biomarker monitoring without invasive procedures.

21 Jan 2026

Scientists Uncover How Cell Growth and Pressure Shape Pancreatic Ducts

Researchers discovered that pressure and cell division rate influence the form of fluid-filled cavities in the developing pancreas.

12 Jan 2026

Muscle Tissue from a 3D Printer – Produced in Zero Gravity

On their way into space, astronauts' bodies deteriorate dramatically in zero gravity. To address this problem and protect our pioneers in space, researchers are looking for realistic test models.

7 Nov 2025

Ingestible Bioprinter Revolutionizes Possibilities for Non-Invasive Tissue Repair

The MEDS device enables non-invasive tissue repair in the GI tract, utilizing innovative bioprinting techniques for effective treatment of internal lesions.

23 Oct 2025

Possible Breakthrough in the Development of Effective Biomaterials

Many hopes rested on so-called tissue engineering: With the help of stem cells, skin and other organs could be grown, thereby enabling better wound healing and better transplants.

19 Sep 2025

ISS National Lab-Sponsored Experiment Tests 3D Bioprinted Tissue for Growing Artificial Livers

To explore how 3D bioprinted liver tissue constructs complete with vascular channels behave in microgravity, the Wake Forest Institute for Regenerative Medicine (WFIRM) is sending an investigation to the International Space Station (ISS).

21 Aug 2025

Magnetic Microneedle Robots Transform Tissue Slicing and Cultivation

In a pioneering development for the biomedical field, a research team led by Yuanjin Zhao from Nanjing Drum Tower Hospital, China, has published a research article in Engineering.

6 Aug 2025

Injectable Hydrogels Use Milk-Derived Vesicles to Promote Tissue Regeneration

Researchers from Columbia Engineering have established a framework for the design of bioactive injectable hydrogels formulated with extracellular vesicles (EVs) for tissue engineering and regenerative medicine applications.

29 Jul 2025

New Stem Cell Reports Perspective: Biomanufacturing in Low Earth Orbit

A new perspective article just published in Stem Cell Reports, “Biomanufacturing in low Earth orbit: A paradigm shift,” features insights from the ISS National Laboratory’s very own Program Director for In-Space Biomanufacturing Davide Marotta, Deputy Chief Scientist Donna Roberts, and Chief Scientist Michael Roberts, as well as leading researchers in regenerative medicine.

3 Jul 2025

Fruit Fly Study Uncovers Key Mechanisms Behind Collective Cell Migration

Researchers uncover how Plexin A and Semaphorin 1b regulate collective cell migration in fruit fly testes, offering insights into organ development, cancer metastasis, and tissue engineering.

26 Jun 2025