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Genomewide CRISPR Screen Reveals Unexpected Structural Protein Link Behind Chronic Colon Inflammation

Since a landmark 2009 study, researchers have known that a common gut bacterium, Bacteroides fragilis, drives colon tumor formation, potentially leading to colorectal cancer, by secreting a toxin that damages the lining of the colon. But until now, the exact mechanism the toxin uses to latch onto those cells remained a mystery.

25 May 2026

New 3D Human Liver Model Mimics Chronic Disease For 30 Days

Researchers developed a 3D liver model that functions for a month, replicating inflammation and fibrosis, crucial for studying liver diseases and therapies.

19 May 2026

Cryo-EM Study Explains Why Coffee Tastes Bitter to Humans

Have you ever wondered why freshly brewed coffee smells so delicious, but tastes bitter?

12 May 2026

New CRISPR System Destroys Diseased Cells With High Precision

A new kind of CRISPR that destroys cells rather than gene editing them has shown potential for killing sick cells while leaving healthy cells untouched.

8 May 2026

New Epigenetic Marker Reveals Lasting Impact of Arsenic Exposure

Public health experts estimate that more than 200 million people worldwide are exposed to arsenic through contaminated drinking water.

5 May 2026

How the Microbiome Shapes Cancer Immunity and Therapy Response

This review examines how the human microbiome regulates anti-tumor immunity through DNA damage, inflammation, immune-cell activity, microbial metabolites, and tumor microenvironment remodeling. It highlights emerging microbiome-based strategies, including FMT, probiotics, prebiotics, engineered bacteria, and live biotherapeutics, while stressing the need for rigorous validation and clinical trials.

29 Apr 2026

Researchers Uncover How the Immune System Teaches the Brain to Avoid Toxins

Researchers from the University of Bonn and University Hospital Bonn uncover vital mechanism for survival.

17 Apr 2026

Molecular Switch AHR Limits Neuron Regeneration and Axon Repair

Researchers from the Icahn School of Medicine at Mount Sinai have discovered a molecular switch in neurons that limits the regrowth of damaged axonal fibers.

3 Apr 2026

Functional Mitochondria Key to Recovery of Dying Photoreceptor Cells

Photoreceptors are specialized cells in the eye that convert light energy into neural signals.

12 Mar 2026

Human 3D Model Shows How the Gut Drives Neurodegeneration

Research on a 3D microfluidic model highlights gut-brain interactions, offering new insights into inflammatory processes linked to neurodegenerative diseases.

18 Feb 2026

New Tool Maps Microbial Activity to Transform Gut Health Research

The gut microbiome is made up of trillions of microbes that play a vital role in keeping us healthy.  A disturbance in the balance of these microbes can contribute to a variety of health conditions, such as inflammatory bowel disease (IBD).

22 Nov 2025

Cyanobacteria Change Their Genetic Activity After Sunset

Cyanobacteria, also referred to as blue-green algae, are found globally in diverse forms, encompassing both single-celled organisms and filamentous chains.

21 Nov 2025

Long-Term Analysis Provides a Novel Look at Harmful Algal Blooms

A long-term analysis shows that a major Oregon reservoir abruptly swapped one type of toxic algae for another midway through the 12-year study period, absent any obvious cause.

12 Nov 2025

St. Jude Researchers Uncover Dual Role of ASPL in Stress Granule Assembly and Disassembly

Stress granules are droplet-like protein hubs that temporarily shield fragile RNA from cellular stresses such as toxins. VCP is a protein essential for breaking up stress granules and has been linked to neurodegenerative diseases.

10 Oct 2025

RfaH Identified as Key to Bacterial Survival in Hostile Environments

Researchers at Umeå University have identified a key molecular player that helps bacteria survive the hostile environment inside the body.

10 Oct 2025

Tracing Origins of Wnt Signaling Through the Lipocone Superfamily

Researchers have described a large set of previously unrecognized enzymatic domains – named the Lipocone superfamily – and outlined their evolutionary pathway from bacterial defense molecules to key players in human development.

10 Sep 2025

Study Uncovers Connection Between Neuronal Overactivation and Parkinson’s Disease

Certain brain cells are responsible for coordinating smooth, controlled movements of the body. But when those cells are constantly overactivated for weeks on end, they degenerate and ultimately die.

28 Aug 2025

Molecular Blueprint Reveals Structure and Delivery of Botulinum Toxin

Researchers at Stockholm University have succeeded in creating a molecular blueprint of how one of the world's most dangerous toxins, botulinum toxin, is structured, stabilized, delivered and released.

28 Aug 2025

Living Bacterial Sensors Translate Environmental Signals into Electrical Data

Researchers at Rice University have engineered E. coli to act as living multiplexed sensors, allowing these genetically modified cells to detect and respond to multiple environmental toxins simultaneously by converting their biological responses into readable electrical signals.

30 Jul 2025