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Engineered Citrus Enzyme Transforms Upstream Precursors Into Bioactive Flavones

Polymethoxyflavones (PMFs) accumulate mainly in the colored outer peel, or flavedo, of citrus fruit and are associated with anticancer, anti-inflammatory, metabolic-protective, and neuroprotective activities reported in experimental studies.

12 Sep 2026

Molecular Circuit Linking Abscisic Acid Signaling to Tanshinone Production Uncovered

Salvia miltiorrhiza, also known as Danshen, is a highly regarded traditional Chinese medicine widely used for treating cardiovascular and cerebrovascular diseases. Its medicinal properties are largely attributed to tanshinones-a group of more than 40 diterpenoid quinone compounds, including tanshinone I, tanshinone IIA, and cryptotanshinone, which predominantly accumulate in the plant's roots.

11 Sep 2026

Homolog Gene Regulation Alters Cell-Cycle Progression for Sprouting Trichomes

Trichomes-tiny hair‑like structures on leaves-serve as physical barriers that protect plants from insect herbivores, UV radiation, excessive water loss, and toxic chemicals.

8 Sep 2026

First Chromosome-Level Genome Unveils Blueprints of Valued Medicinal Compounds

Spuriopimpinella brachycarpa, known locally as Dayeqin or Shanqincai, has long been used in traditional medicine to treat colds, indigestion, abdominal pain, and cough.

8 Sep 2026

RNA Polymerase Successfully Transcribes an Expanded Genetic Alphabet

All known life on earth utilizes the same genetic alphabet, consisting of four letters. Now, researchers at University of California San Diego have demonstrated that one of biology's most essential enzymes can accurately read and transcribe an expanded, eight-letter genetic alphabet.

4 Sep 2026

Scientists Uncover Unexpected Feature of Human DNA Organization

A new study led by Francesca Storici, a professor in the School of Biological Sciences and faculty member of the Parker H. Petit Institute for Bioengineering and Bioscience, has uncovered an unexpected feature of human DNA linked to gene activity and the physical organization of DNA.

3 Sep 2026

Protein Interaction Helps Senescent Cells Survive Aging and Cellular Stress

Senescent cells - cells that have stopped dividing but remain metabolically active - can accumulate with age and contribute to chronic inflammation and tissue dysfunction

2 Sep 2026

Cell Study Unveils Method to Spot Tiny Molecular Protein Fluctuations

Imagine a brain teaser where the challenge is to spot the difference between two nearly identical sandcastles. The only difference? The removal of three grains of sand.

2 Sep 2026

Novel Chemical Probes Improve Capture of Elusive DNA Repair Proteins

PARylation is a reversible post-translational modification in which PARP enzymes use NAD+ to assemble PAR chains on proteins. These chains can function as signaling scaffolds that recruit proteins involved in DNA repair, chromatin organization, transcription, and stress responses.

1 Sep 2026

Advanced Computational Methods Map Metabolite Binding Proteins Across Cellular Contexts

Endogenous metabolites participate in nearly every fundamental biological process, serving not only as metabolic intermediates but also as signaling molecules that influence physiology and disease.

1 Sep 2026

Researchers Track Harmful Post COVID Autoantibodies to Specific B Cells

When the immune system encounters a virus, it produces antibodies designed to recognize and eliminate the invader.

31 Aug 2026

Machine Learning Tool Uncovers Epigenome Patterns Without Predefined Labels

In a study recently published in Nature Communications, researchers from Berlin, Potsdam, and Jena present a new method for analyzing the epigenome, the genome's control system that determines which genes are switched on and off.

28 Aug 2026

Researchers Outline Quantitative Principles of Cell Signaling Time Codes

For decades, biologists assumed that cells transmit instructions mainly through the concentration of signaling molecules - the higher the level, the stronger the response.

27 Aug 2026

Mutation Stalls Immature Brain Cell Maturation Leading to Aggressive Gliomas

Scientists at St. Jude Children's Research Hospital have shown that specific brain cells respond differently to the H3.3 K27M, a mutation in the histone H3.3 protein that drives many cases of diffuse midline glioma (DMG), depending on the cell's location in the developing brain.

27 Aug 2026

Mice Studies Prove Engineered Molecules Eradicate Tumors Within Eleven Days

A two-headed molecule designed by Stanford Medicine researchers hijacks one of the most common protein drivers of B-cell lymphoma, flipping it from its role as a promoter of cell growth into an arbiter of cell death.

22 Aug 2026

Powerful Imaging Technique Captures Gene Transcription Inside Living Organisms

All living things have a fleet of tiny copy machines that turn instructions from DNA into RNA, the molecules responsible for helping build proteins that keep organisms alive.

21 Aug 2026

Study Shows How Zombie Cells Drive Chronic Inflammaging-and Age-Related Diseases

When our immune system detects a pathogen or injury, it sets off biological alarm bells. This alert brings in a variety of immune and other cells to deal with the threat and heal any harm done.

21 Aug 2026

Single-Cell Study Decodes Ancient Plant Partnership With Soil Fungi

Scientists at VIB and Ghent University have produced the first high-resolution, cell-by-cell map of how tomato roots respond to colonization by arbuscular mycorrhizal fungi.

19 Aug 2026

New Research Links Chronic Inflammation to Tumor Microenvironment Epigenetic Changes

Immune checkpoint inhibitors have revolutionized cancer treatment, yet many colorectal tumors remain resistant. Even among patients who initially respond, more than half eventually develop resistance, highlighting the need to better understand how tumors evade immune attack.

19 Aug 2026

Study Shows How Compact Viral Structures Boost Protein Yields for mRNA Vaccines

A research team led by Director KIM V. Narry at the Center for RNA Research within the Institute for Basic Science (IBS) has discovered compact viral RNA elements that can make mRNA more stable and increase protein production.

17 Aug 2026