Cell Biology

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New CAR T therapy could be more effective and less toxic against neuroblastoma

CAR T therapy has transformed the treatment for leukemia. Regrettably, the therapy is not effective enough to treat solid tumors, like neuroblastoma.

22 Jan 2021

Cancer cells can exchange and recombine their genetic material, shows study

Evolution within groups of tumor cells follows the principles of natural selection, as evolution in pathogenic microbes.

22 Jan 2021

SARS-CoV-2 virus may enter and replicate in human cells by targeting cellular processes

The SARS-CoV-2 virus may enter and replicate in human cells by exploiting newly-identified sequences within cell receptors, according to work from two teams of scientists.

22 Jan 2021

Researchers identify a new way to stop COVID-19 virus

While the world awaits broad distribution of COVID-19 vaccines, researchers at Ohio University just published highly significant and timely results in the search for another way to stop the virus -- by disrupting its RNA and its ability to reproduce.

22 Jan 2021

Immunity of COVID-19 patients may rely on antibodies from previous coronavirus infections

The results of a study led by Northern Arizona University and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest the immune systems of people infected with COVID-19 may rely on antibodies created during infections from earlier coronaviruses to help fight the disease.

22 Jan 2021

Study: Phase separated droplets have many important functions in cells

Autophagy is a fundamental cellular process by which cells capture and degrade their own dysfunctional or superfluous components for degradation and recycling.

22 Jan 2021

Electrical trigger sites in the brain change with experience, shows study

To process information in our brains, nerve cells produce brief electrical impulses, called action potentials, triggered from one highly specialized region.

22 Jan 2021

Immature dendritic cells in young children can induce robust immune responses

A new study performed by scientists from Ludwig-Maximilians-Universitaet Muenchen (LMU) has demonstrated that putatively immature dendritic cells in young children can trigger powerful immune responses. The findings may result in better vaccination protocols.

21 Jan 2021

Study identifies new mode of male endocrine disruption due to environmental arsenic exposure

Arsenic exists ubiquitously in an organic or inorganic state in the environment. General populations are commonly exposed to arsenic by digestion.

21 Jan 2021

Investigational antisense medicine lowers disease burden, reduces myeloma cell abundance in mice

Many patients with multiple myeloma, a type of blood cancer, eventually develop resistance to one treatment after another. That's in part because cancer stem cells drive the disease -- cells that continually self-renew. If a therapy can't completely destroy these malignant stem cells, the cancer is likely to keep coming back.

From UC San Diego 21 Jan 2021

New form of cultivated meat promises more natural flavor and texture

Researchers have created a type of cultivated meat using a process that offers more natural flavor than other substitutes to conventional animal meat.

20 Jan 2021

New technique helps detect dangerous histamine levels in fish samples

For people buying food products, there is no way to determine the safety and quality of food that is delivered to their plates by existing distribution systems.

20 Jan 2021

COVID-19 virus triggers antibody response from prior coronavirus infections

According to the results of a study, the immune systems of COVID-19 patients may depend on antibodies that were produced during infections from previous coronaviruses to help combat the disease.

20 Jan 2021

Study reveals genetic variants that increase the risk of nocturnal enuresis

In a large-scale study of Danish children and young people, researchers from Aarhus University have for the first time found genetic variants that increase the risk of nocturnal enuresis - commonly known as bedwetting or nighttime incontinence. The findings provide completely new insights into the processes in the body causing this widespread phenomenon.

20 Jan 2021

Viral relatives of SARS-CoV-2 can evolve to evade the human immune system

Scientists have shown that two species of seasonal human coronavirus related to SARS-CoV-2 can evolve in certain proteins to escape recognition by the immune system, according to a study published today in eLife.

20 Jan 2021

Functions of gamma delta T cells are regulated by sugars and fat Gene, shows study

The team led by Bruno Silva Santos, Principal Investigator and Deputy Director of the Instituto de Medicina Molecular João Lobo Antunes (iMM) and Professor at the Faculdade de Medicina da Universidade de Lisboa, discovered that the functions of a subtype of white blood cells - gamma delta T cells - are regulated by metabolic resources, namely sugars and fat.

20 Jan 2021

Study shows how nonmalignant cells adapt to harsh tumor microenvironment

Cells need energy to survive and thrive. Generally, if oxygen is available, cells will oxidize glucose to carbon dioxide, which is very efficient, much like burning gasoline in your car. However, even in the presence of adequate oxygen, many malignant cells choose instead to ferment glucose to lactic acid, which is a much less efficient process.

20 Jan 2021

Researchers define cancer invasion machinery orchestrated by cancer gene

Researchers at the University of Helsinki have defined a cancer invasion machinery, which is orchestrated by a frequently mutated cancer gene called Ras. When signaling from Ras protein becomes abnormally high, like it does in many cancers, this switches on the cellular machinery that helps the cancer cells to depart from the tissue from which the cells have developed.

20 Jan 2021

New method shows how pharmaceuticals induce cancer cell death

Cancer cells are smart when it comes to anti-cancer drugs, evolving and becoming resistant to even the strongest chemotherapies over time.

20 Jan 2021

New computational technique accurately differentiates between normal and cancer cells

Scientists have created a new method to precisely differentiate between data from a wide range of normal cells and cancer cells found inside tumor samples.

19 Jan 2021

Cell Biology

New CAR T therapy could be more effective and less toxic against neuroblastoma

Cancer cells can exchange and recombine their genetic material, shows study

SARS-CoV-2 virus may enter and replicate in human cells by targeting cellular processes

Researchers identify a new way to stop COVID-19 virus

Immunity of COVID-19 patients may rely on antibodies from previous coronavirus infections

Study: Phase separated droplets have many important functions in cells

Electrical trigger sites in the brain change with experience, shows study

Immature dendritic cells in young children can induce robust immune responses

Study identifies new mode of male endocrine disruption due to environmental arsenic exposure

Investigational antisense medicine lowers disease burden, reduces myeloma cell abundance in mice

New form of cultivated meat promises more natural flavor and texture

New technique helps detect dangerous histamine levels in fish samples

COVID-19 virus triggers antibody response from prior coronavirus infections

Study reveals genetic variants that increase the risk of nocturnal enuresis

Viral relatives of SARS-CoV-2 can evolve to evade the human immune system

Functions of gamma delta T cells are regulated by sugars and fat Gene, shows study

Study shows how nonmalignant cells adapt to harsh tumor microenvironment

Researchers define cancer invasion machinery orchestrated by cancer gene

New method shows how pharmaceuticals induce cancer cell death

New computational technique accurately differentiates between normal and cancer cells

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