Cell Biology

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New CRISPR-Cas9 based method for directed protein evolution

"Directed evolution" is the process by which scientists produce tailor-made proteins for cell biology, physiology and biomedicine in the laboratory.

28 May 2020

New technique enables high-resolution visualization of tumor heterogeneity patterns

Malignant tumors consume nutrients and oxygen faster than healthy cells. To do so, they recruit blood vessels in their environment.

28 May 2020

New study outlines the mechanisms behind cell fusion

Scientists have known for a decade that cells that fuse with others to perform their essential functions - such as muscle cells that join together to make fibers - form long projections that invade the territory of their fusion partners.

28 May 2020

AXT offer Fluicell’s innovative range of tissue engineering systems in Australia & NZ

AXT are proud to announce that they have just expanded their life science product portfolio with the addition of Fluicell’s innovative tissue engineering systems. The new agreement will see AXT exclusively distribute their Biopixlar and BioPen product lines in Australia and New Zealand.

From AXT Pty Ltd 28 May 2020

Damped circadian oscillations observed in the absence of KaiA protein in cyanobacterium

Circadian rhythms are driven by a highly autonomous, self-sustaining circadian clock in our cells, telling us when to sleep or wake up in a 24-hour cycle.

27 May 2020

Study discovers how protein inhibits tumor development in mice

Proteins are found throughout our cells and regulate a lot of biological processes that are important for our survival.

27 May 2020

Nanodevices give unprecedented peek into how cells change with time

For the first time, scientists have introduced minuscule tracking devices directly into the interior of mammalian cells, giving an unprecedented peek into the processes that govern the beginning of development.

From University of Bath 27 May 2020

New minimally invasive method allows cells to be sampled over time

At any given moment, a variety of dynamic processes occur inside a cell, with many developing over time. Because current research methods for gene profiling or protein analysis destroy the cell, study is confined to just that one moment in time, and researchers are unable to return to the cell to examine how things change beyond that snapshot.

27 May 2020

The eye launches an immune response in the lens following injury

The lens of the eye is an unusual organ. Unlike most of the body's organs, blood vessels don't reach the lens. If they did, they'd obscure our vision and we wouldn't be able to see. The lack of vasculature led scientists to believe immune cells, which travel via the bloodstream, couldn't get to this part of the body either.

27 May 2020

Mechanically rejuvenated fibroblasts show promise in stem cell engineering

Fibroblasts synthesize the collagen, creating the structural framework for animal tissues, and play a significant role in the process of wound healing.

27 May 2020

Determining the optimal age of stem cells to restore heart tissue

Biophysicists have successfully established the optimal age of reprogrammed stem cells that are appropriate for restoring heart tissues.

27 May 2020

New sequencing method helps map the spatial arrangement of DNA

A sequencing technique helps to map the spatial arrangement of DNA in the cell nucleus, revealing which regions of the genome are at greater risk of mutation.

27 May 2020

Pre-existing genes can promote metastasis

Cancer can sometimes remain dormant, but it usually metastasizes and spreads to new sites in the body.

27 May 2020

New model mimics early embryonic stages of the human brain

We know a lot about the human brain, but very little about how it is formed. In particular, the stages from the second to the seventh week of embryonic development have so far been virtually unknown territory to brain researchers.

26 May 2020

New tool shows how microbes influence health and promote diseases

Scientists from the Quadram Institute and Earlham Institute have developed a unique tool that is helping them to translate the complex communication that takes place between the body and the microbiome.

25 May 2020

Gene associated with thinness may play a role in resisting weight gain

Some people can remain slim easily, irrespective of their diet, while others might be dieting and working out at the gym to maintain their shape.

25 May 2020

Biochemical and computational methods for large-scale protein-arginine methylation analysis

Methylation (namely addition of a methyl group) of arginine amino acid residues of proteins is a post-translational modification (PTM) catalyzed by a family of nine enzymes called Protein Arginine Methyl-Transferases (PRMTs).

23 May 2020

Nanobowl-stabilized liposomes are less leaky than regular liposomes

For many years, researchers have analyzed the use of liposomes, which are hollow spheres composed of lipid bilayers, to transmit chemotherapy drugs to tumor cells.

22 May 2020