Cell Biology

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Patient-Derived Organoids can Help Identify Effective Personalized Cancer Therapies

Researchers created organoids from cancer cells to reduce the need for trial and error in identifying effective cancer treatments in one of many cancer studies scheduled for presentation this week at Digestive Disease Week (DDW) 2023.

9 May 2023

Understanding How Interleukin-6 Contributes to Suppress Allergic Asthma and Atopy

The immune system has a biological telecommunications system -; small proteins known as interleukins that send signals among the leukocyte white blood cells to control their defense against infections or nascent cancer.

8 May 2023

New Model for the Evolution of Higher Brain Functions and Behaviors in Insects

Researchers have proposed a new model for the evolution of higher brain functions and behaviors in the Hymenoptera order of insects.

8 May 2023

Tokyo Tech Researchers Discover How Surface Chemistry can Influence Adhesion of Bacterial Cells

The biofilm-forming bacteria E. coli adheres firmly to hydrophobic and hydrophilic protein-adsorbing self-assembling monolayers (SAMs) and weakly to hydrophilic protein-resisting SAMs, uncovered a recent study by Tokyo Tech researchers.

8 May 2023

Cancer Stem Cell Test can Accurately Decide More Effective Treatments for Glioblastoma Patients

New multi-institutional phase 3 clinical trial data published May 2 in Cell Reports Medicine found that a cancer stem cell test can accurately decide more effective treatments and lead to increased survival for patients with glioblastoma, a deadly brain tumor.

8 May 2023

Manipulating Brain Cells via Light Irradiation

An international research team, comprising scientists from DZNE, University Hospital Bonn, the Netherlands, and the US has been awarded a US$ 1.3 million grant by the "Human Frontier Science Program" to investigate brain immune cells and manipulate them via light irradiation.

8 May 2023

Analyzing the Complex Sequence of Events Involved in Beta-Arrestin Interactions

Proteins that work like air traffic controllers, controlling the flow of signals in and out of human cells, have been examined in unparalleled detail for the first time using modern microscope techniques.

5 May 2023

Innate Tumor Suppression Mechanism Uncovered

The p53 gene is one of the most important in the human genome: the only role of the p53 protein that this gene encodes is to sense when a tumor is forming and to kill it.

5 May 2023

Immune Evasion Mechanism of TNBC Cells Discovered

Freiburg researchers discover a mechanism by which cancer cells escape the immune system.

5 May 2023

Understanding How Supernumerary Chromosomes Arise

The majority of chromosomes have existed for millions of years.

5 May 2023

Revealing the Conserved Role of Serotonin in Maintaining Germline Quality

Worms may not be depressed. However, this does not prevent them from benefiting from antidepressants.

5 May 2023

Remodeling in the Cell Membrane Alters Enzyme Activity Involved in Alzheimer’s

Adding long-chain fatty acids can thicken cell membranes and alter the activity of a key enzyme, as LMU scientists have demonstrated in cell cultures.

5 May 2023

Study Reveals an Immunological Strategy to Overcome Microbiome-Related Immunotherapy Resistance

Cancer immunotherapy has transformed the treatment of many types of cancer. Yet, for reasons that remain poorly understood, not all patients get the same benefit from these powerful therapies.

4 May 2023

Study Uncovers Cancer-Like Changes in Mitochondrial Disease of Newborns

A study found that a mitochondrial disease of newborns shows cancer-like changes in proliferating cells, causing tissues to age prematurely.

4 May 2023

Mini Organs Provide New Insights Into Fibrolamellar Carcinoma

Scientists of the Princess Máxima Center for pediatric oncology and Hubrecht Institute in the Netherlands have revealed new scientific insights into the features of fibrolamellar carcinoma (FLC), a rare type of childhood liver cancer

4 May 2023

New CAR T Strategy Offers a Dual-Targeting Mechanism to Fight Bone Metastatic Prostate Cancer

Prostate cancer frequently metastasizes to the bone and is incurable. Moffitt Cancer Center researchers are working to identify new treatment options for this subset of patients.

4 May 2023

Study Reveals That Transcriptional Buffering Occurs in Rett Syndrome Nerve Cells

Every cell in our body is able to turn genes (DNA) on or off, producing RNA, but when genes are 'turned on' to the wrong level it can result in a variety of health conditions.

3 May 2023

Inhibiting a Tiny RNA Could Help Improve Immune, Bone, and Muscle Health With Age

Inhibiting a tiny RNA whose levels significantly increase with age, along with problems like weaker bones and sagging muscles, may be a way to keep our bodies more youthful and healthy, scientists say.

3 May 2023

Deep Learning Model for Label-Free Identification of Different Cancer Cells

Cancer cells that initiate metastasis, or the spread of the disease from its primary location, are different from cancer cells that stay in the original tumor. Distinguishing metastasis-initiating cell types can determine the severity of cancer and help medical practitioners decide on a course of treatment.

3 May 2023

Analyzing the Cell Division in Stem Cells

What appears to be a simple task for a cell—splitting in two—is indeed a complex series of engineering puzzles. To produce two working cells, a splitting cell has to maneuver its interiors in such a way that the appropriate components will end up in each cell.

3 May 2023

Cell Biology

Patient-Derived Organoids can Help Identify Effective Personalized Cancer Therapies

Understanding How Interleukin-6 Contributes to Suppress Allergic Asthma and Atopy

New Model for the Evolution of Higher Brain Functions and Behaviors in Insects

Tokyo Tech Researchers Discover How Surface Chemistry can Influence Adhesion of Bacterial Cells

Cancer Stem Cell Test can Accurately Decide More Effective Treatments for Glioblastoma Patients

Manipulating Brain Cells via Light Irradiation

Analyzing the Complex Sequence of Events Involved in Beta-Arrestin Interactions

Innate Tumor Suppression Mechanism Uncovered

Immune Evasion Mechanism of TNBC Cells Discovered

Understanding How Supernumerary Chromosomes Arise

Revealing the Conserved Role of Serotonin in Maintaining Germline Quality

Remodeling in the Cell Membrane Alters Enzyme Activity Involved in Alzheimer’s

Study Reveals an Immunological Strategy to Overcome Microbiome-Related Immunotherapy Resistance

Study Uncovers Cancer-Like Changes in Mitochondrial Disease of Newborns

Mini Organs Provide New Insights Into Fibrolamellar Carcinoma

New CAR T Strategy Offers a Dual-Targeting Mechanism to Fight Bone Metastatic Prostate Cancer

Study Reveals That Transcriptional Buffering Occurs in Rett Syndrome Nerve Cells

Inhibiting a Tiny RNA Could Help Improve Immune, Bone, and Muscle Health With Age

Deep Learning Model for Label-Free Identification of Different Cancer Cells

Analyzing the Cell Division in Stem Cells

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