Cell Biology

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Research Deepens Our Understanding of Circadian Rhythm Regulation

New research from a multidisciplinary team helps to illuminate the mechanisms behind circadian rhythms, offering new hope for dealing with jet lag, insomnia and other sleep disorders.

27 Apr 2023

Highly Tissue-Specific lincRNA Markers Could Indicate the Presence of Disease

Our genetic code includes over 15,000 specific sections that can be made into molecules called lincRNAs.

27 Apr 2023

Getting Insights into Parkinson’s Patients’ Brain Cells Through Stem Cell Research

When the first symptoms of Parkinson’s disease are experienced by a patient, the disease has been evolving for a long period, and the patient might already have lost half of a certain kind of nerve cells in the brain.

27 Apr 2023

Cross-Resistant Bacteria from Agricultural Animal as First Line of Defense in Human

New research headed by the University of Oxford has revealed that overuse of antimicrobials in livestock production can lead to the evolution of bacteria more resistant to the first line of the human immune response. The findings were published today in eLife. They show that farmed chickens and pigs could possess huge reservoirs of cross-resistant bacteria, which are capable of powering future epidemics.

27 Apr 2023

Novel Mathematical Framework Evaluates the Dynamics of Adaptive Immune Evasion

Recent research published in the journal eLife proposes a theory for how cancer cells might actively adapt to the immune system to become resistant to immunotherapy.

27 Apr 2023

Modulation of ERK Signaling Could be Used to Stimulate Regeneration

Why do some animals regenerate lost tissues after injury while others don't? Researchers from the lab of Kerstin Bartscherer (Osnabrück University and formerly Hubrecht Institute) and Ashley Seifert (University of Kentucky) studied spiny mice, which have a remarkable regenerative capacity, to answer this question.

26 Apr 2023

New, Improved Dual Version of Living Yeast Biosensor to Detect All Peptide Variants

Biosensors-;sensors that can detect biological samples-;are powerful tools for understanding the function, composition, and structure of biochemical molecules.

26 Apr 2023

Researchers Develop 9CN-Rhodol-Based Activatable Raman Probes With High Sensitivity

Raman imaging offers a greater potential for detecting multiple enzyme activities than fluorescence imaging, demonstrate Tokyo Tech researchers by developing 9CN-rhodol-based activatable Raman probes using a novel mechanism for Raman signal activation.

26 Apr 2023

Computational Models can Help Determine the Identities and Roles of Individual Neurons

Investigators at Cedars-Sinai have created computer-generated models to bridge the gap between "test tube" data about neurons and the function of those cells in the living brain.

26 Apr 2023

Capturing Viruses in a Lipid Trap

Viruses like influenza A and Ebola invade human cells in a number of steps. In an interdisciplinary approach, research teams from Heidelberg University and Heidelberg University Hospital investigated the final stages of viral penetration using electron tomography and computer simulations.

26 Apr 2023

Green Algae in Swedish Lakes Offer New Clues to the Amazing Paths of Evolution

By studying green algae in Swedish lakes, a research team, led by Lund University in Sweden, has succeeded in identifying which environmental conditions promote multicellularity.

26 Apr 2023

A Study on Neural Crest Cell

As per a new study from the University of Bath, a neural crest cell (a kind of stem cell) starts with the capacity to differentiate into numerous specialist cell kinds, but it also seems to retain the ability to “change its mind” and differentiate again when the situations are appropriate.

26 Apr 2023

Previously Unknown Protein Reveals RNA Repair Mechanism in Humans

Ribonucleic acids (RNAs) are single-stranded molecules that are found in all living organisms’ cells. As “transcripts” of human genes, mRNAs, for instance, play a role in the translation of genetic information by bearing the instructions for the production of a protein in their own sequence.

26 Apr 2023

Generating the Landscape of m6A in a Mouse Embryo

RNA, particularly mRNA, has recently received some attention as the major component of the COVID-19 vaccines.

26 Apr 2023

Mathematical Mechanism Behind the Rugged Structures at Cell Boundaries

The mathematical and biological mechanisms underlying the rugged structures at cell boundaries present in tissues like the kidneys and nasal glands have been discovered.

26 Apr 2023

CloneTracer Reveals a Differentiation Landscape of Acute Myeloid Leukemia

Researchers have developed a new method to distinguish between cancerous and healthy stem cells and progenitor cells from samples of patients with acute myeloid leukemia (AML), a disease driven by malignant blood stem cells that have historically been difficult to identify.

25 Apr 2023

Metabolic Network Compatibility Not Likely the Limiting Factor in Prokaryotic Endosymbiosis

"One of the great mysteries of biology," says Eric Libby, former SFI Postdoctoral Fellow, now an associate professor at the Integrated Science Lab (IceLab), Umeå University in Sweden, "is eukaryogenesis, or how eukaryotes arose." Scientists consider this to be a period of major evolutionary transition, critical to our understanding of the history and evolution of life on Earth.

25 Apr 2023

Blocking Necroptosis Could Lead to the Inhibition of Cancer Metastasis

A new editorial paper was published in Oncotarget's Volume 14 on April 10, 2023, entitled, "Tumor necroptosis promotes metastasis through modulating the interplay between tumor and host immunity."

25 Apr 2023

New Powerful Resource to Understand the Biology of Extracellular RNA

An international team led by researchers at Baylor College of Medicine with the National Institutes of Health Extracellular RNA Communication Consortium and the Bogdan Mateescu laboratory at the ETH Zürich and University of Zürich has developed a new powerful resource to study extracellular RNA (exRNA), a novel form of cell-to-cell communication.

24 Apr 2023