Drug Discovery & Pharmaceuticals

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T-cell-based vaccine strategy provides broader protection against influenza

As Americans begin pulling up their sleeves for an annual flu vaccine, researchers at the University of Wisconsin-Madison have provided new insights into an alternative vaccine approach that provides broader protection against seasonal influenza.

24 Sep 2020

Nanoparticle SARS-CoV-2 tool could accelerate the search for drugs

A team of scientists from the National Center for Advancing Translational Sciences and Naval Research Laboratory in Washington, D.C., has developed a new tool that mimics how SARS-CoV-2 -- the virus that causes COVID-19 -- infects a cell, information that could potentially speed the search for treatments against the disease.

22 Sep 2020

Defined regulatory framework needed for developing live biotherapeutic products

The Pharmabiotic Research Institute (PRI), Europe's only regulatory expertise centre for the development of microbiome-based drug products, has announced the publication of a review titled "Live biotherapeutic products: the importance of a defined regulatory framework".

18 Sep 2020

Smart drug delivery system may help treat spinal cord injuries and other neurological disorders

A Rutgers-led team has created a smart drug delivery system that reduces inflammation in damaged nervous tissues and may help treat spinal cord injuries and other neurological disorders.

From Rutgers University 18 Sep 2020

Innovations assist compound management labs using Acoustix tubes

Ziath has released a module to enable their Mirage, Cube or Express tube readers to decode Brooks Acoustix tubes.

From Ziath Ltd 18 Sep 2020

Protein inhibitors neutralize SARS-CoV-2 infection in cell culture

Using innovative computer-based approaches, researchers have developed protein inhibitors that block the interaction between the SARS-CoV-2 virus and human cell receptor ACE2.

10 Sep 2020

Novel method produces anti-inflammatory substances with controlled quality

Anti-inflammatory substances based on components of human cells could one day improve treatment in patients. Researchers at the Institute of Pharmacy at Martin Luther University Halle-Wittenberg (MLU) have developed a method for producing those substances with controlled quality.

10 Sep 2020

Safe antibiotic levels can help fight the spread of drug-resistant bacteria

New research reveals current understanding of safe antibiotic levels in rivers may not prevent evolution of antibiotic resistance and fully protect human health. The study suggests the need to introduce thresholds to help fight the spread of resistant bacteria.

From University of Exeter 4 Sep 2020

New method delivers promising anti-rejection drug to area surrounding a grafted heart

For patients who receive a heart transplant in the near future, the old adage, "Good things come in small packages," may become words to live by.

4 Sep 2020

Understanding skin damage caused by rubbing could lead to better topical skin treatments

Understanding the skin damage caused by rubbing could lead to better topical skin treatments and help prevent the formation of new routes for viral and bacterial infection.

31 Aug 2020

Drug-like compounds previously developed to fight SARS may also work against COVID-19

An extensive search and testing of current drugs and drug-like compounds have revealed compounds previously developed to fight SARS might also work against COVID-19.

28 Aug 2020

Study shows how individualization with pharmacogenomics could impact COVID-19 treatments

Over the past few months, a number of drugs have been under investigation to treat COVID-19 without well-established safety or data to support these claims.

28 Aug 2020

Scientists identify antigen valencies that work best in vaccine designs for HIV, SARS-CoV-2

Designing a vaccine starts with finding the right ingredients. Every infectious agent has molecules, called antigens, that the immune system could potentially recognize and attack. So scientists must carefully consider which antigens should go into a vaccine.

28 Aug 2020

New syringe technology for subcutaneous injection of viscous formulations

MIT researchers have developed a simple, low-cost technology to administer powerful drug formulations that are too viscous to be injected using conventional medical syringes.

25 Aug 2020

Researchers describe new approach involving "antivitamins" to develop new antibiotics

Antibiotics are among the most important discoveries of modern medicine and have saved millions of lives since the discovery of penicillin almost 100 years ago.

25 Aug 2020

Microsoft's AI supports the development of Vaxine's COVAX-19 vaccine

Given the global urgency of the COVID-19 pandemic, Microsoft's AI for Health program has stepped in to support the development and potential deployment of Vaxine's COVAX-19™ vaccine with a philanthropic grant.

25 Aug 2020

Researchers find associations of lifelong antimicrobial drug use with saliva microbiota diversity

The human microbiota plays an important role in health and well-being by assisting in digestion, producing nutrients, resisting invading pathogens and regulating metabolism and the immune system.

25 Aug 2020

Researchers add a component to make cancer vaccine more effective

Jefferson researchers developing a cancer vaccine to prevent recurrences of gastric, pancreatic, esophageal and colon cancers have added a component that would make the vaccine more effective.

25 Aug 2020

New study shows promise for developing COVID-19 vaccine

When news about a novel coronavirus switched from a chronicle of its progress in China to headlines about a worldwide COVID-19 pandemic, Gladstone Institutes scientist Nadia Roan, PhD, was in the midst of publishing several papers on T cells and their role in HIV spread and long-lasting infections.

24 Aug 2020

Cashew shell compound shows therapeutic potential for demyelinating diseases

In laboratory experiments, a chemical compound found in the shell of the cashew nut promotes the repair of myelin, a team from Vanderbilt University Medical Center reports today in the Proceedings of the National Academy of Sciences.

From Vanderbilt University 19 Aug 2020

Drug Discovery & Pharmaceuticals

T-cell-based vaccine strategy provides broader protection against influenza

Nanoparticle SARS-CoV-2 tool could accelerate the search for drugs

Defined regulatory framework needed for developing live biotherapeutic products

Smart drug delivery system may help treat spinal cord injuries and other neurological disorders

Innovations assist compound management labs using Acoustix tubes

Protein inhibitors neutralize SARS-CoV-2 infection in cell culture

Novel method produces anti-inflammatory substances with controlled quality

Safe antibiotic levels can help fight the spread of drug-resistant bacteria

New method delivers promising anti-rejection drug to area surrounding a grafted heart

Understanding skin damage caused by rubbing could lead to better topical skin treatments

Drug-like compounds previously developed to fight SARS may also work against COVID-19

Study shows how individualization with pharmacogenomics could impact COVID-19 treatments

Scientists identify antigen valencies that work best in vaccine designs for HIV, SARS-CoV-2

New syringe technology for subcutaneous injection of viscous formulations

Researchers describe new approach involving "antivitamins" to develop new antibiotics

Microsoft's AI supports the development of Vaxine's COVAX-19 vaccine

Researchers find associations of lifelong antimicrobial drug use with saliva microbiota diversity

Researchers add a component to make cancer vaccine more effective

New study shows promise for developing COVID-19 vaccine

Cashew shell compound shows therapeutic potential for demyelinating diseases

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