Drug Discovery & Pharmaceuticals

RSS

Reactivating divergent signaling pathways to enhance cancer treatment

In order for cancer to form in the human body, normal cells must acquire multiple mutations before they develop toward the disease. It was previously believed that these mutations acted in concert in the progression of cancer.

23 Jul 2020

New startup launched to overcome the challenge of delivering next-generation therapeutics

Harvard University's Office of Technology Development (OTD) and the Harvard T.H. Chan School of Public Health today announced the launch of Vesigen Therapeutics, a startup company that aims to overcome the challenge of delivering next-generation therapeutics, such as gene-editing complexes, RNA molecules, and other large proteins, to intracellular targets in specific tissues of interest.

23 Jul 2020

Quality of lab procedures has a big impact on discovery of effective drugs

In their quest to find new drugs to treat deadly diseases, scientists study millions of molecules at high speed at the same time. Often it is enzymes that are investigated as targets in these 'high-throughput' screenings.

From University of Bath 22 Jul 2020

Josep Carreras Institute creates spin-off to develop CAR-T based therapies for leukemia

The Josep Carreras Leukaemia Research Institute, a public centre pertaining to the Generalitat de Catalunya's (Government of Catalonia) CERCA network, has created the OneChain Immunotherapeutics spin-off, the aim of which is to develop new immuno-oncological therapeutic tools with various preclinical candidates, based on CAR-T technology for different tumors, such as cortical T-cell acute lymphoblastic leukemia (coT-ALL), a rare subtype of leukemia that mainly affects children, and which has a poor prognosis.

21 Jul 2020

Novel nano drug candidate kills triple negative breast cancer cells

Researchers at the University of Arkansas have developed a new nano drug candidate that kills triple negative breast cancer cells.

21 Jul 2020

UC Davis Health tests new antibody combination as potential treatment for COVID-19

Timothy Albertson, chair of internal medicine and specialist in pulmonary and critical care, is leading efforts at UC Davis Health to test a new antibody cocktail (REGN-COV2) as a prevention and treatment for COVID-19.

From The University of California, Davis 21 Jul 2020

A new method to fortify shellfish for tackling human nutrient defiiciencies

Cambridge scientists have developed a new way to fortify shellfish to tackle human nutrient deficiencies which cause severe health problems across the world. The team is now working with major seafood manufacturers to further test their microencapsulation technology, or "Vitamin Bullets".

20 Jul 2020

Research may help design new, highly selective generation of Alzheimer's drugs

With over 1.2 million people affected in Germany alone and over 50 million people worldwide, Alzheimer's disease, also referred to simply as Alzheimer's, is one of the greatest medical and social challenges of our time.

20 Jul 2020

Emerging hydrogel material could improve delivery of oral drugs

An emerging hydrogel material with the capacity to degrade and spontaneously reform in the gastrointestinal tract could help researchers develop more effective methods for oral drug delivery.

From Lehigh University 20 Jul 2020

Beautyberry leaf extract boosts drug's activity antibiotic-resistant staph bacteria

Scientists discovered a compound in the leaves of a common shrub, the American beautyberry, that boosts an antibiotic's activity against antibiotic-resistant staph bacteria. Laboratory experiments showed that the plant compound works in combination with oxacillin to knock down the resistance to the drug of methicillin-resistant Staphylococcus aureus, or MRSA.

17 Jul 2020

Changes in glioblastoma cells influence the effect of different drugs, shows study

Therapies for treating glioblastoma brain cancer can be delivered with greater precision and existing drugs can be used in new ways.

15 Jul 2020

Study suggests ways to improve antibiotic allergy registrations

Antibiotics are among the most commonly prescribed medications, but in determining the most appropriate prescription for a patient, doctors and pharmacists often rely on inaccurate records of the patient's antibiotic allergies.

15 Jul 2020

Innovative robot can help develop medicated chewing gum

Medicated chewing gum has been recognised as a new advanced drug delivery method but currently there is no gold standard for testing drug release from chewing gum in vitro.

15 Jul 2020

Investigational COVID-19 vaccine is safe, generates neutralizing antibody activity in healthy adults

An investigational vaccine, mRNA-1273, designed to protect against SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), was generally well tolerated and prompted neutralizing antibody activity in healthy adults, according to interim results published online today in The New England Journal of Medicine.

15 Jul 2020

New radiopharmaceutical offers precise diagnosis and treatment of prostate cancer in preclinical studies

Researchers have developed a new pair of agents that show exceptional effectiveness for precision diagnosis and treatment of prostate cancer in preclinical studies.

14 Jul 2020

UTMB researchers uncover new mechanism for designing dengue therapeutics

A multidisciplinary team from The University of Texas Medical Branch at Galveston has uncovered a new mechanism for designing antiviral drugs for dengue virus. The study is currently available in Proceedings of the National Academy of Sciences.

14 Jul 2020

NIH establishes clinical trial network to test vaccines and monoclonal antibodies for COVID-19

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has established a new clinical trial network that aims to enroll thousands of volunteers in large-scale clinical trials testing a variety of investigational vaccines and monoclonal antibodies intended to protect people from COVID-19.

14 Jul 2020

Altimmune reports positive results on intranasal COVID-19 vaccine candidate

Altimmune, Inc., a clinical-stage biopharmaceutical company, has announced positive results from the preclinical studies conducted in mice at the University of Alabama at Birmingham of its intranasal COVID-19 vaccine candidate, AdCOVID.

14 Jul 2020

Researchers discover promising drug candidate for treatment of brain disorders

Researchers at IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology) discovered a novel chemical compound, which has the potential to became a new drug for the treatment of core symptoms of brain disorders like Down syndrome and autism.

13 Jul 2020

New drug enables the immune system to attack ovarian cancer, TGen study shows

A drug known as SP-2577 could help enable the body's own immune system to attack ovarian cancer, according to a study led by the Translational Genomics Research Institute, an affiliate of City of Hope.

13 Jul 2020

Drug Discovery & Pharmaceuticals

Reactivating divergent signaling pathways to enhance cancer treatment

New startup launched to overcome the challenge of delivering next-generation therapeutics

Quality of lab procedures has a big impact on discovery of effective drugs

Josep Carreras Institute creates spin-off to develop CAR-T based therapies for leukemia

Novel nano drug candidate kills triple negative breast cancer cells

UC Davis Health tests new antibody combination as potential treatment for COVID-19

A new method to fortify shellfish for tackling human nutrient defiiciencies

Research may help design new, highly selective generation of Alzheimer's drugs

Emerging hydrogel material could improve delivery of oral drugs

Beautyberry leaf extract boosts drug's activity antibiotic-resistant staph bacteria

Changes in glioblastoma cells influence the effect of different drugs, shows study

Study suggests ways to improve antibiotic allergy registrations

Innovative robot can help develop medicated chewing gum

Investigational COVID-19 vaccine is safe, generates neutralizing antibody activity in healthy adults

New radiopharmaceutical offers precise diagnosis and treatment of prostate cancer in preclinical studies

UTMB researchers uncover new mechanism for designing dengue therapeutics

NIH establishes clinical trial network to test vaccines and monoclonal antibodies for COVID-19

Altimmune reports positive results on intranasal COVID-19 vaccine candidate

Researchers discover promising drug candidate for treatment of brain disorders

New drug enables the immune system to attack ovarian cancer, TGen study shows

Expert Insights: HiMedia Labs on Advancing Nucleic Acid Extraction Across Industries

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Latest in Genomics