Genomics

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Researchers use zebrafish to identify role of gene involved in cardiac rhythm

Researchers have used the zebrafish (Danio rerio) to identify the role of a gene involved in cardiac rhythm, which could help explain the fundamentals of what it takes to make a human heartbeat.

17 Feb 2021

Combining cholesterol-lowering medications and lifestyle interventions may yield better benefits

Combining healthy lifestyle interventions reduces heart disease through beneficial effects on different lipoproteins and associated cholesterols, according to a study published February 9 in eLife.

17 Feb 2021

Genetic testing technology is extremely unreliable in detecting very rare genetic variants

According to a new study, a technology that is extensively used by commercial genetic testing firms is “extremely unreliable” in identifying very rare variants.

From University of Exeter 16 Feb 2021

Gene-based blood test may predict treatment success in people with metastatic melanoma

A test that monitors blood levels of DNA fragments released by dying tumor cells may serve as an accurate early indicator of treatment success in people in late stages of one of the most aggressive forms of skin cancer, a new study finds.

From New York University (NYU) 15 Feb 2021

Study uncovers how harmless E.coli gut bacteria turn deadly

An international team of scientists has determined how harmless E.coli gut bacteria in chickens can easily pick up the genes required to evolve to cause a life-threatening infection.

From University of Bath 15 Feb 2021

Innovative system allows complete study of SARS-CoV-2 mutant spectrum by ultrasequencing

Researchers have designed a program that allows the complete study of the SARS-CoV-2 mutant spectrum by ultrasequencing.

15 Feb 2021

New AI-based method produces new diversity of AAV capsids for optimized gene therapy

Dyno Therapeutics has demonstrated the use of AI to created an unparalleled range of adeno-associated virus capsids that can evade the immune system.

15 Feb 2021

Enzyme in fruit fly larvae plays key role in waking up brain stem cells

Researchers studying an enzyme in fruit fly larvae have found that it plays an important role in waking up brain stem cells from their dormant 'quiescent' state, enabling them to proliferate and generate new neurons.

12 Feb 2021

Genomic test helps identify prostate cancer patients who may benefit from hormone therapy

A commercially available genomic test may help oncologists better determine which patients with recurrent prostate cancer may benefit from hormone therapy, according to new research from the Johns Hopkins Kimmel Cancer Center and 15 other medical centers.

12 Feb 2021

New tool reveals potentially risky DNA alterations at site of CRISPR gene repair

Scientists have developed an affordable, downloadable app that scans for potential unintended mistakes when CRISPR is used to repair mutations that cause disease.

12 Feb 2021

Daytime napping is partly regulated by a person's genes

How often a person takes daytime naps, if at all, is partly regulated by their genes, according to new research led by investigators at Massachusetts General Hospital (MGH) and published in Nature Communications.

11 Feb 2021

Inherited genetic variation plays a role in how patients respond to cancer immunotherapy

For all their importance as a breakthrough treatment, the cancer immunotherapies known as checkpoint inhibitors still only benefit a small minority of patients, perhaps 15 percent across different types of cancer. Moreover, doctors cannot accurately predict which of their patients will respond.

11 Feb 2021

Study examines the largest and most diverse genetic sequencing data sets

Researchers at the University of Maryland School of Medicine (UMSOM) and their colleagues published a new analysis today in the journal Nature from genetic sequencing data of more than 53,000 individuals, primarily from minority populations.

11 Feb 2021

Scientists use new approach to avert drug resistance in glioblastomas

In far too many cases over the years, scientists have discovered promising new cancer treatments, only to report later that the tumor cells found ways to become resistant. These disappointing results have made overcoming drug resistance a major goal in cancer research.

11 Feb 2021

Researchers identify tumor suppressor gene involved in stress response

Even the larvae of the Drosophila fly contain adult progenitor cells. And these cells are the only ones that are preserved throughout the growth and are responsible for the development of adult tissues and organs.

11 Feb 2021

Researchers program genome tool to target specific histone proteins

If finding a needle in a haystack is hard enough, then one should try finding a particular molecule on the needle.

11 Feb 2021

Unusual DNA folding leads to higher mutation rates

DNA sequences that can fold into shapes other than the classic double helix tend to have higher mutation rates than other regions in the human genome.

From Penn State University 10 Feb 2021

Study provides insights into genetic landscape of common inherited kidney disease

A study has described genetic changes in patients with the most common form of hereditary kidney disease that affects an estimated 12.5 million people worldwide.

10 Feb 2021

New study facilitates the use of gene editing technique on plants

A new study performed by the IBMCP of UPV University enables the use of the CRISPR genomic editing technique on plants.

9 Feb 2021

New platform may accelerate genomic medicine research, drug therapies

A research team, headed by Cleveland Clinic, has designed a novel personalized genomic medicine platform that would help speed up genomic medicine studies as well as genome-informed drug discovery. The results of the new study have been recently published in the Genome Biology journal.

9 Feb 2021

Genomics

Researchers use zebrafish to identify role of gene involved in cardiac rhythm

Combining cholesterol-lowering medications and lifestyle interventions may yield better benefits

Genetic testing technology is extremely unreliable in detecting very rare genetic variants

Gene-based blood test may predict treatment success in people with metastatic melanoma

Study uncovers how harmless E.coli gut bacteria turn deadly

Innovative system allows complete study of SARS-CoV-2 mutant spectrum by ultrasequencing

New AI-based method produces new diversity of AAV capsids for optimized gene therapy

Enzyme in fruit fly larvae plays key role in waking up brain stem cells

Genomic test helps identify prostate cancer patients who may benefit from hormone therapy

New tool reveals potentially risky DNA alterations at site of CRISPR gene repair

Daytime napping is partly regulated by a person's genes

Inherited genetic variation plays a role in how patients respond to cancer immunotherapy

Study examines the largest and most diverse genetic sequencing data sets

Scientists use new approach to avert drug resistance in glioblastomas

Researchers identify tumor suppressor gene involved in stress response

Researchers program genome tool to target specific histone proteins

Unusual DNA folding leads to higher mutation rates

Study provides insights into genetic landscape of common inherited kidney disease

New study facilitates the use of gene editing technique on plants

New platform may accelerate genomic medicine research, drug therapies

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