Genomics

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Scientists identify new drug target for treating Hutchinson-Gilford progeria syndrome

Researchers have discovered a promising treatment method for Hutchinson-Gilford progeria syndrome (HGPS)—a debilitating genetic disorder that accounts for rapid and premature aging in children.

3 Feb 2021

Researchers gain a deep insight into the evolutionary history of bitter receptors

To evaluate the chemical composition of food from a physiological point of view, it is important to know the functions of the receptors that interact with food ingredients. These include receptors for bitter compounds, which first evolved during evolution in bony fishes such as the coelacanth.

3 Feb 2021

Genome architectural changes linked to B cell-related blood cancers

Flaws in the way chromosomes are packed into antibody-producing B-cells seem to play a key role in the development of B-cell-related blood cancers.

2 Feb 2021

Severe genetic immunodeficiency reversed by a rare DNA change

Researchers have revealed how a rare DNA change rebalanced the immune system of patients with a life-threatening genetic immunodeficiency.

2 Feb 2021

Scientists identify specific genes associated with post-traumatic stress disorder

A research team has found 18 specific, fixed positions on chromosomes (called loci) that seem to be linked to post-traumatic stress disorder (PTSD).

29 Jan 2021

Scientists discover the origin of rare genetic syndrome

Improvements in DNA sequencing have revealed a rare syndrome triggered by changes in the SATB1gene.

29 Jan 2021

Researchers identify key molecule involved in immune regulation

The majority of the molecules in human bodies support the immune system to keep individuals healthy but they do so without reacting excessively, as this may otherwise drive the immune cells to cause problems, like autoimmune disorders.

29 Jan 2021

Ocean acidification could be affecting lobsters on a molecular scale

The American lobster, which supports the most valuable fishery in North America, maybe more susceptible to the effects of climate change than previously thought, according to a new study published in Ecology and Evolution.

29 Jan 2021

3D genome study reveals molecular regulatory mechanisms of human brain evolution

A team led by Prof. SU Bing from the Kunming Institute of Zoology (KIZ) of the Chinese Academy of Sciences (CAS), Prof. LI Cheng from Peking University, and Prof. ZHANG Shihua from the Academy of Mathematics and Systems Science of CAS has reported the highest resolution by far of the 3D genome of the primate brain, and demonstrated the molecular regulatory mechanisms of human brain evolution through cross-species multi-omics analysis and experimental validation. The study was published in Cell.

29 Jan 2021

Targeting glycoprotein could improve response to immune checkpoint therapy

It was an unexpected discovery that started with an analysis of more than 1,000 genes. The question: why game-changing cancer immunotherapy treatments work for only a fraction of patients.

29 Jan 2021

Research shows how breast cancer cells evade immune attacks

Scientists from Indiana University have discovered how breast cancer cells evade immune cells to survive.

28 Jan 2021

Study shows TALEN is five times more efficient than CRISPR-Cas9 tool

Using single-molecule imaging, scientists have compared the CRISPR-Cas9 and TALEN genome editing tools.

28 Jan 2021

Researchers produce a high-quality reference sequence of the switchgrass genome

Gardeners and farmers around the country recognize that crop varieties grow best in certain regions. Most plant species have adapted to their local environments; for example, crop and ornamental seeds sold for the upper Midwest are often very different than those bred for Texas.

28 Jan 2021

Genetic changes in tumors could help predict patient's response to immunotherapy drugs

Researchers at the Francis Crick Institute, the UCL Cancer Institute, and the Cancer Research UK Lung Cancer Centre of Excellence have identified genetic changes in tumours which could be used to predict if immunotherapy drugs would be effective in individual patients.

28 Jan 2021

New computational method simplifies the analysis of gene-environmental interactions

Scientists from Weill Cornell Medicine and the Ithaca campus at Cornell University have designed a novel computational technique for analyzing environmental and genetic interactions and how they affect disease risk.

28 Jan 2021

Unique proteomics-based technology can help diagnose breast cancer more accurately

Breast cancer could be identified more precisely than existing methods using blood specimens and exclusive proteomics-based technology.

28 Jan 2021

Researchers publish a complex genome analysis of switchgrass

Biologists believe they are one step closer to a long-held goal of making a cheap, widely available plant a source for energy and fuel, meaning one of the next big weapons in the battle against climate change may be able to trace its roots to the side of a Texas highway.

28 Jan 2021

Genomics

Scientists identify new drug target for treating Hutchinson-Gilford progeria syndrome

Researchers gain a deep insight into the evolutionary history of bitter receptors

Genome architectural changes linked to B cell-related blood cancers

Severe genetic immunodeficiency reversed by a rare DNA change

Scientists identify specific genes associated with post-traumatic stress disorder

Scientists discover the origin of rare genetic syndrome

Researchers identify key molecule involved in immune regulation

Ocean acidification could be affecting lobsters on a molecular scale

3D genome study reveals molecular regulatory mechanisms of human brain evolution

Targeting glycoprotein could improve response to immune checkpoint therapy

Research shows how breast cancer cells evade immune attacks

Study shows TALEN is five times more efficient than CRISPR-Cas9 tool

Researchers produce a high-quality reference sequence of the switchgrass genome

Genetic changes in tumors could help predict patient's response to immunotherapy drugs

New computational method simplifies the analysis of gene-environmental interactions

Unique proteomics-based technology can help diagnose breast cancer more accurately

Researchers publish a complex genome analysis of switchgrass

Study shows how abnormal number of chromosomes could become a weak point for cancer cells

New search engine helps compare samples in different microbiomes

New variant of CRISPR-Cas9 tool expands genomic editing in plants

Expert Insights: HiMedia Labs on Advancing Nucleic Acid Extraction Across Industries

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Latest in Genomics