Genomics

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Study reveals complete genome of major parasitic flowering plant

On January 22 in Current Biology, a team of Harvard-led researchers presented the most complete genome yet assembled of one of the major Rafflesiaceae lineages, Sapria himalayana.

25 Jan 2021

New protocol identifies mismatch repair deficiency

Researchers have developed a new integrated genetic/epigenetic DNA-sequencing protocol known as MultiMMR that can identify the presence and cause of mismatch repair (MMR) deficiency in a single test from a small sample of DNA in the colon, endometrial, and other cancers.

22 Jan 2021

Cancer cells can exchange and recombine their genetic material, shows study

Evolution within groups of tumor cells follows the principles of natural selection, as evolution in pathogenic microbes.

22 Jan 2021

Study defines the most crucial genes that Increase risk of breast cancer

Genetic inheritance affects the likelihood of developing breast cancer. Some genes are already known to increase cancer risk; other genes are suspected to be involved, but not to what extent. It is crucial to clarify this issue to improve prevention since it opens the way to more personalized follow-up and screening programs.

22 Jan 2021

Immunity of COVID-19 patients may rely on antibodies from previous coronavirus infections

The results of a study led by Northern Arizona University and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest the immune systems of people infected with COVID-19 may rely on antibodies created during infections from earlier coronaviruses to help fight the disease.

22 Jan 2021

Venom of Tiger Rattlesnakes may advance genetic science

Among all rattlesnake species, the Tiger Rattlesnake has the simplest yet most lethal venom. Now, a new study performed by a team of researchers can describe the genetics behind the venomous bite of the Tiger Rattlesnake.

21 Jan 2021

Antibiotic resistance may be spreading much faster than expected

Pathogenic bacteria in humans are developing resistance to antibiotics much faster than expected. Now, computational research at Chalmers University of Technology, Sweden, shows that one reason could be significant genetic transfer between bacteria in our ecosystems and to humans. This work has also led to new tools for resistance researchers.

21 Jan 2021

Researchers discover genetic risk factor for stroke

A research team from Geisinger Health System has detected a common genetic variant as a risk factor for stroke, particularly in patients aged more than 65.

20 Jan 2021

New technique helps detect dangerous histamine levels in fish samples

For people buying food products, there is no way to determine the safety and quality of food that is delivered to their plates by existing distribution systems.

20 Jan 2021

COVID-19 virus triggers antibody response from prior coronavirus infections

According to the results of a study, the immune systems of COVID-19 patients may depend on antibodies that were produced during infections from previous coronaviruses to help combat the disease.

20 Jan 2021

Food choice may accelerate aging and shorten lifespan of fruit flies

Having a choice of foods may accelerate aging and shorten the lifespan of fruit flies, according to a study published today in the open-access eLife journal.

20 Jan 2021

Study reveals genetic variants that increase the risk of nocturnal enuresis

In a large-scale study of Danish children and young people, researchers from Aarhus University have for the first time found genetic variants that increase the risk of nocturnal enuresis - commonly known as bedwetting or nighttime incontinence. The findings provide completely new insights into the processes in the body causing this widespread phenomenon.

20 Jan 2021

Researchers define cancer invasion machinery orchestrated by cancer gene

Researchers at the University of Helsinki have defined a cancer invasion machinery, which is orchestrated by a frequently mutated cancer gene called Ras. When signaling from Ras protein becomes abnormally high, like it does in many cancers, this switches on the cellular machinery that helps the cancer cells to depart from the tissue from which the cells have developed.

20 Jan 2021

New computational technique accurately differentiates between normal and cancer cells

Scientists have created a new method to precisely differentiate between data from a wide range of normal cells and cancer cells found inside tumor samples.

19 Jan 2021

New genome resource helps study genetic traits in major crops

Thanks to a new genome resource created for green millet, researchers will be able to study the genetics of crucial traits in crops, like sorghum and maize, in a much better way. The resource was created by three RIKEN scientists.

18 Jan 2021

Study shows how specific gene mutations cause different types of diseases

Renowned cancer experts have resolved a query of how different types of mutations in a single gene are responsible for causing various types of diseases.

15 Jan 2021

Scientists detect genomic DNA changes even in sun-protected skin

Researchers have quantified the diverse types of genomic DNA variations that take place in skin cells and found that mutations from UV light is common.

15 Jan 2021

Researchers use heat map data to reverse engineer chromosome models

Genome analysis can provide information on genes and their location on a strand of DNA, but such analysis reveals little about their spatial location in relation to one another within chromosomes -- the highly complex, three-dimensional structures that hold genetic information.

15 Jan 2021

Targeting RNA splicing can trigger antiviral immune pathways in triple-negative breast cancers

Researchers at Baylor College of Medicine have discovered how therapeutics targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers (TNBC) to trigger tumor cell death and signal the body's immune response.

15 Jan 2021