Genomics

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Genes inherited from parents are responsible for severe COVID-19

For the first time, scientists have discovered the genetic predisposition of severe COVID-19 disease.

24 Feb 2021

DNA origami helps track gene-editing processes

The genetic scissors, known as CRISPR/Cas9, the finding that received a Nobel Prize in Chemistry, occasionally cut in places that they are not intended to target.

24 Feb 2021

Researchers identify a type of RNA as therapeutic target for Huntington's treatment

Huntington's disease is caused by a mutation in the Huntingtin gene (HTT), which appears in adults and features motor, cognitive and psychiatric alterations.

24 Feb 2021

Cre-controlled CRISPR makes conditional gene inactivation more easier

To discover the function of a gene researchers turn it off and observe the consequences. Often genes have multiple functions that differ depending on a tissue and age.

24 Feb 2021

Study provides new information on occurrence of DVL2 gene defect in dogs

A recent genetic study at the University of Helsinki provides new information on the occurrence of a DVL2 gene defect associated with a screw tail and its relevance to canine constitution and health.

24 Feb 2021

Interbacterial toxins may contribute to bacterial genetic diversity

A toxin produced by bacteria as a defense mechanism causes mutations in target bacteria that could help them survive, according to a study published today in eLife.

24 Feb 2021

New gene-editing technique allows for pre-programming of sequential edits

Researchers from the University of Illinois Chicago have discovered a new gene-editing technique that allows for the programming of sequential cuts -- or edits -- over time.

24 Feb 2021

Induced pluripotent stem cells show promise to revive wildlife species

A new article shares a significant development in conservation—one that may make the difference between extinction and survival for wildlife species.

23 Feb 2021

Sufficient rest during holidays restores functions associated with DNA regulation

According to a recent study, sufficient rest during vacation time restored functions linked to DNA regulation in shift workers deprived of sleep.

23 Feb 2021

Environmental DNA can be used to measure genetic diversity of Pacific salmon, trout

Scientists at Oregon State University and the U.S. Forest Service have demonstrated that DNA extracted from water samples from rivers across Oregon and Northern California can be used to estimate genetic diversity of Pacific salmon and trout.

23 Feb 2021

Study reveals specialized mechanism for translation of mitochondrial genome into proteins

An international collaboration among researchers from Finland, Sweden, UK and the USA has captured ribosomes translating messenger RNA expressed from the maternally inherited mitochondrial genome.

23 Feb 2021

Jumping genes are an important force in the creation of new genes during evolution, shows study

In the same way that Lego pieces can be arranged in new ways to build a variety of structures, genetic elements can be mixed and matched to create new genes, according to new research.

23 Feb 2021

Researchers use CRISPR to tinker with corn kernel numbers

Corn--or maize--has changed over thousands of years from weedy plants that make ears with less than a dozen kernels to the cobs packed with hundreds of juicy kernels that we see on farms today. Powerful DNA-editing techniques such as CRISPR can speed up that process.

23 Feb 2021

Genes may impact the timing of labor

A new study illuminates how a gene called HAND2 may have a hand in the timing of human labor.

23 Feb 2021

A functional test to measure the effect of inherited gene variants in breast and ovarian cancer

Researchers at Mayo Clinic have combined results from a functional test measuring the effect of inherited variants in the BRCA2 breast and ovarian cancer gene with clinical information from women who received genetic testing to determine the clinical importance of many BRCA2 variants of uncertain significance (VUS).

22 Feb 2021

Color morphs speak of the coral's resilience to high temperatures

Anyone who visits the Great Barrier Reef in Australia, Southeast Asia's coral triangle, or the reefs of Central America, will surely speak of how stunning and vibrant these environments are.

22 Feb 2021

Genes could help determine the intensity of neutralizing antibodies to COVID-19 virus

While neutralizing antibodies form in less than two weeks of a COVID-19 infection, their intensity and durability can differ from one individual to another.

22 Feb 2021

Advanced explainable AI to solve regulatory instructions encoded in DNA

Researchers at the Stowers Institute for Medical Research, in collaboration with colleagues at Stanford University and Technical University of Munich have developed advanced explainable artificial intelligence (AI) in a technical tour de force to decipher regulatory instructions encoded in DNA.

19 Feb 2021

First-in-human clinical trial to test safety, efficacy of gene therapy for Alzheimer's disease

Researchers at University of California San Diego School of Medicine have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer's disease (AD) or Mild Cognitive Impairment (MCI), a condition that often precedes full-blown dementia.

From UC San Diego 19 Feb 2021

Almost one in five people lack key protein in their muscle fibers

About one in five individuals do not have the α-actinin-3 protein in their muscle fiber.

18 Feb 2021

Genomics

Genes inherited from parents are responsible for severe COVID-19

DNA origami helps track gene-editing processes

Researchers identify a type of RNA as therapeutic target for Huntington's treatment

Cre-controlled CRISPR makes conditional gene inactivation more easier

Study provides new information on occurrence of DVL2 gene defect in dogs

Interbacterial toxins may contribute to bacterial genetic diversity

New gene-editing technique allows for pre-programming of sequential edits

Induced pluripotent stem cells show promise to revive wildlife species

Sufficient rest during holidays restores functions associated with DNA regulation

Environmental DNA can be used to measure genetic diversity of Pacific salmon, trout

Study reveals specialized mechanism for translation of mitochondrial genome into proteins

Jumping genes are an important force in the creation of new genes during evolution, shows study

Researchers use CRISPR to tinker with corn kernel numbers

Genes may impact the timing of labor

A functional test to measure the effect of inherited gene variants in breast and ovarian cancer

Color morphs speak of the coral's resilience to high temperatures

Genes could help determine the intensity of neutralizing antibodies to COVID-19 virus

Advanced explainable AI to solve regulatory instructions encoded in DNA

First-in-human clinical trial to test safety, efficacy of gene therapy for Alzheimer's disease

Almost one in five people lack key protein in their muscle fibers

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