Genomics

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New technique reveals the tricks that cancer cells use to avoid immunotherapies

By harnessing the immune system against cancer, immunotherapies have revolutionized the way some types of cancer are treated. But most patients--across cancer types--do not respond, and in most cases, scientists are at a loss as to why.

2 Mar 2021

CRISPR-Cas9 can safeguard future crops under stress from variable climate conditions

Gene editing technology will play a vital role in climate-proofing future crops to protect global food supplies, according to scientists at The University of Queensland.

2 Mar 2021

New function of regulatory gene may lead to more productive plant varieties

A team of researchers has confirmed that the SUPERMAN gene also establishes the number of flowers in leguminous plants.

1 Mar 2021

Bioinformatics approach accurately tracks the origin of synthetic genetic code

Monitoring the origin of the synthetic genetic code has not been easy, but it can be performed via bioinformatics or deep-learning computational techniques.

1 Mar 2021

UChicago-based team shares new details about Genomic Data Commons

The National Cancer Institute's Genomic Data Commons (GDC), launched in 2016 by then-Vice President Joseph Biden and hosted at the University of Chicago, has become one of the largest and most widely used resources in cancer genomics, with more than 3.3 petabytes of data from more than 65 projects and over 84,000 anonymized patient cases, serving more than 50,000 unique users each month.

1 Mar 2021

Researchers identify gene variant associated with childhood asthma

Researchers at Henry Ford Health System, as part of a national asthma collaborative, have identified a gene variant associated with childhood asthma that underscores the importance of including diverse patient populations in research studies.

1 Mar 2021

Increased levels of OAS1 protein may reduce the severity of COVID-19

Researchers at the Lady Davis Institute (LDI) at the Jewish General Hospital have discovered that increased levels of the protein OAS1 are associated with reduced mortality and less severe disease requiring ventilation among patients with COVID-19.

1 Mar 2021

Absence of TRIM37 protein boosts genetic instability in patients with Mulibrey syndrome

Researchers from the Andalusian Centre for Molecular Biology and Regenerative Medicine (CABIMER), in collaboration with the Swiss Institute for Experimental Cancer Research (ISREC) have studied the mechanisms behind the higher tendency of people with Mulibrey syndrome to develop tumors.

1 Mar 2021

Two new Alzheimer’s genes discovered

AZoLifeSciences speaks to researchers from Tianjin Medical University about their latest research that led to the discovery of two new genes that are linked to Alzheimer's disease.

From Tianjin Medical University 1 Mar 2021

Researchers sequence 64 human genomes at high resolution

After the successful conclusion of the “Human Genome Project”, an international research team has sequenced a total of 64 human genomes at high resolution.

26 Feb 2021

Study reveals new functions of ENDOU enzymes

The majority of organisms feature the series of ENDOU enzymes, but despite this fact, the functions of these enzymes have not been properly understood.

25 Feb 2021

Multidisciplinary approaches for data management in omics research

Bioinformatics, and by extension omic sciences - the collective disciplines that are dependent on the use of extensive datasets of biological information - present a challenge of data management for researchers all over the world.

25 Feb 2021

Setting new standards for the exchange of human omics data

Genomics, transcriptomics, proteomics, metabolomics, and others... The "omics" technologies keep revolutionizing medicine and biomedical sciences.

25 Feb 2021

New method to track how yellow fever mosquito moves through environment

The yellow fever mosquito (Aedes aegypti) is the main vector of deadly diseases like dengue fever, chikungunya, and the Zika virus, which result in hundreds of thousands of deaths worldwide each year.

25 Feb 2021

Genes inherited from parents are responsible for severe COVID-19

For the first time, scientists have discovered the genetic predisposition of severe COVID-19 disease.

24 Feb 2021

DNA origami helps track gene-editing processes

The genetic scissors, known as CRISPR/Cas9, the finding that received a Nobel Prize in Chemistry, occasionally cut in places that they are not intended to target.

24 Feb 2021

Researchers identify a type of RNA as therapeutic target for Huntington's treatment

Huntington's disease is caused by a mutation in the Huntingtin gene (HTT), which appears in adults and features motor, cognitive and psychiatric alterations.

24 Feb 2021

Cre-controlled CRISPR makes conditional gene inactivation more easier

To discover the function of a gene researchers turn it off and observe the consequences. Often genes have multiple functions that differ depending on a tissue and age.

24 Feb 2021

Study provides new information on occurrence of DVL2 gene defect in dogs

A recent genetic study at the University of Helsinki provides new information on the occurrence of a DVL2 gene defect associated with a screw tail and its relevance to canine constitution and health.

24 Feb 2021

Interbacterial toxins may contribute to bacterial genetic diversity

A toxin produced by bacteria as a defense mechanism causes mutations in target bacteria that could help them survive, according to a study published today in eLife.

24 Feb 2021