Genomics

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Breaking Down the Complex Mechanisms of Neurodegeneration

By using a novel neuronal cell culture model, researchers at the University of Zurich have illuminated the complex mechanisms behind neurodegeneration.

23 Feb 2024

Retrotransposon-Based PRINT Technique Holds Potential for Precise Gene Insertion

The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job knocking out genes to cure hereditary disease.

22 Feb 2024

Mechanism of Cancer Drug Targeting Tumor Suppressor Genes Unveiled

Researchers have revealed the mechanism of a drug shown to be effective in treating certain types of cancer, which targets a protein modification silencing the expression of multiple tumor suppressor genes.

22 Feb 2024

Genetic Insights and Conservation Challenges of Nara's Sacred Deer

In a world where human activities have left an indelible mark on ecosystems, the preservation of species and natural landscapes has become an urgent global concern.

22 Feb 2024

Insights From the Ogasawara Islands Biodiversity Study

The Ogasawara Islands are a chain of tiny volcanic islands located thousands of km South of Tokyo, deep within the world's largest ocean.

21 Feb 2024

The Promise of siRNA Nanomedicine for HIV Treatment

Society learned about the usefulness of mRNA during the COVID-19 pandemic when scientists and medical professionals leveraged its power to deliver a vaccine for the virus within a year.

21 Feb 2024

Ancient DNA Study Finds Evidence of Chromosomal Disorders

By analyzing ancient DNA, an international team of researchers have uncovered cases of chromosomal disorders, including what could be the first case of Edwards syndrome ever identified from prehistoric remains.

21 Feb 2024

MIP Discovery Closes £7M Series a Financing to Drive Commercialization in Cell and Gene Therapy Space

MIP Discovery, an innovative developer of non-biological affinity reagents designed to accelerate the development and production of cell and gene therapies, today announced it has closed a £7 million GBP (~$9 million USD) Series A financing round, led by Mercia Ventures.

21 Feb 2024

Genetic Clusters Linked to Type 2 Diabetes and Complications

The relationship between genetic variations and disease in order to create novel medications and therapies.

20 Feb 2024

Bulls Guide Research into Male Fertility Genetics

One in eight couples worldwide are unable to conceive within a year, or lifelong due to infertility, making it a common issue.

19 Feb 2024

Telomerase's Double-Edged Sword: Preventing DNA Repair Mishaps

The natural ends of chromosomes appear alarmingly like broken DNA, much as a snapped spaghetti strand is difficult to distinguish from its intact counterparts.

16 Feb 2024

Researchers Identify Genes Linked to Genomic Instability and DNA Damage

More than one hundred key genes linked to DNA damage have been uncovered through systematic screening of nearly 1,000 genetically modified mouse lines, in a new study published today (14 February) in Nature.

16 Feb 2024

New Understanding of DNA Damage and Disease Risk

Researchers identified 145 genes that are essential for the health of the genome and potential treatments for human genomic disorders.

15 Feb 2024

Hi-C Sequencing Unveils Phage-Host Dynamics in Soil Ecosystems

Bacteriophages-;viruses that infect bacteria-;are common in soil ecosystems.

14 Feb 2024

Unleashing the Potential of CRISPR-COPIES

The last ten years have seen tremendous advancements in CRISPR/Cas systems. These precise genome editing tools can be used for more than just gene therapy and transgenic crop development.

13 Feb 2024

Unlocking RNA Secrets: New Method Exposes Gene Expression's Hidden Hurdles

A new study demonstrates that a method may identify, for the first time, the frequency and precise location of a molecular occurrence known as "backtracking" across the genetic material (genome) of any species.

12 Feb 2024

GWAS Identifies Key Genetic Factors for Lassa Fever Susceptibility and Severity

While combing through the human genome in 2007, computational geneticist Pardis Sabeti made a discovery that would transform her research career.

9 Feb 2024

New Research Sheds Light on Divergent Roles of Paralogous RNA Helicases

Genetic expression, often leading to protein synthesis, requires a complex coordination of molecular machinery across several stages.

9 Feb 2024

Accelerating Genetic Research - The Story Behind One-pot DTECT

Dr Pierre Billon, PhD, grew increasingly frustrated with the lengthy turnaround times and high costs associated with obtaining genetic analysis from specialized private laboratories

8 Feb 2024

Scientists Predict DNA Mutations Causing Extra Fingers, Hearts

Our genomes provide the instructions for proper growth and development. Millions of genomic switches, known as enhancers, control the location and timing of gene expression, which in turn ensures the correct proteins are made in the right cells at the right time throughout our lives.

7 Feb 2024