Genomics

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Study presents top 100 research questions facing plant science

Without plants, we'd have no air to breathe or food to eat, yet plant science lingers in the shadowy wings while other fields take center stage.

20 Mar 2023

Genomic study helps to better understand the origins, history of Tibetan and Sherpa ethnic groups

The Tibetan Plateau, the highest and largest plateau above sea level, is one of the harshest environments settled by humans.

20 Mar 2023

Study suggests new strategy for treating arrhythmogenic cardiomyopathy

University of Utah Health scientists have corrected abnormal heart rhythms in mice by restoring healthy levels of a protein that heart cells need to establish connections with one another.

20 Mar 2023

Study may help identify new sex-specific treatments for depression

Depression is widely reported to be more common in women than in men, with women twice as likely to receive a diagnosis than men.

20 Mar 2023

Decreased viral infection severity in females linked to extra copy of epigenetic regulator

It has long been known that viral infections can be more severe in males than females, but the question as to why has remained a mystery – until possibly now.

20 Mar 2023

Cancer cells use new DNA repair mechanism to recover from next-generation cancer radiation therapy

A team of scientists led by Dr. Kei-ichi TAKATA from the Center for Genomic Integrity within the Institute for Basic Science (IBS), has discovered a new type of DNA repair mechanism that cancer cells use to recover from next-generation cancer radiation therapy.

20 Mar 2023

Previously unknown genetic causes of three rare conditions discovered

Using a new computational approach they developed to analyze large genetic datasets from rare disease cohorts, researchers at the Icahn School of Medicine at Mount Sinai and colleagues have discovered previously unknown genetic causes of three rare conditions: primary lymphedema (characterized by tissue swelling), thoracic aortic aneurysm disease, and congenital deafness.

20 Mar 2023

Using a programmable control switch to deliver therapeutic RNA molecules to target cells

Using an RNA sensor, MIT engineers have designed a new way to trigger cells to turn on a synthetic gene.

17 Mar 2023

Novel genetics tool for mining impact assessment and biomonitoring of endangered chimpanzees

The western chimpanzees of Guinea are threatened by mining activities. Using a novel genetic approach, UZH researchers and an international team have collected information on population size and community structure of the endangered species.

17 Mar 2023

Genomic analysis shows Ashaninka people are not as homogeneous as previously reported

The Ashaninka are the most numerous Indigenous people living in the rainforests of Peru and Brazil where they inhabit a crucial area between the Andes and sources of the Amazon River. And yet, despite the size of the population and their importance in the past and present, their genetic history has remained understudied.

17 Mar 2023

Researchers discover previously unknown genetic causes of three rare conditions

17 Mar 2023

Potential approach to improve solid tumor T cell therapy

Researchers at the Perelman School of Medicine at the University of Pennsylvania have been working on a preclinical study that focuses on a new strategy that uses a “one-two punch” to assist T cells in attacking solid tumors.

17 Mar 2023

The impact of genome doubling on the development of cancer

Since a single cell has 2–3 m of DNA, the only method to store it is in tight coils. The answer is chromatin, a DNA-protein complex that is wrapped around histone proteins.

17 Mar 2023

Novel web-based tool deoptimizes genetic sequences based on different codon usage

A new software tool developed by Texas Biomedical Research Institute and collaborators can help scientists and vaccine developers quickly edit genetic blueprints of pathogens to make them less harmful.

16 Mar 2023

Age-related sarcopenia prevented by AAV1.NT-3 gene therapy

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 5, entitled, "AAV1.NT-3 gene therapy prevents age-related sarcopenia."

16 Mar 2023

Study evaluates the use of DNA metabarcoding to identify fish eggs

A new study published in PeerJ Life & Environment and featured in the International Association for Biological Oceanography Hub evaluates the use of DNA metabarcoding to identify fish eggs.

14 Mar 2023

Gene that regulates cadmium distribution between leaf and grain in rice

Due to its accumulation in crops, specifically rice, cadmium (Cd), a hazardous heavy metal contaminant of cultivated land, poses a threat to human health. Thus, it is vital to develop methods to prevent Cd from accumulating in rice grains.

14 Mar 2023

Rice biologists embark on a three-year project to create genetically encoded antibiotics

Synthetic biologists at Rice University are embarking on a three-year project to create "genetically encoded antibiotics," strands of RNA that bacteria will readily copy and share that will selectively kill only disease-causing, pathogenic bacteria.

14 Mar 2023

Understanding the factors that impact CRISPRa efficiency

Investigators, from the Wellcome Sanger Institute and partners, utilized human stem cells and neurons to explore what attributes impact how well CRISPR activation works for different sets of genes.

14 Mar 2023

TurboID-based proximity labeling in meiotic cells of Arabidopsis thaliana

During meiosis, reshuffling of genetic information between homologous chromosomes through meiotic recombination creates variable gametes and hence genetic variation in offsprings.

14 Mar 2023

Genomics

Study presents top 100 research questions facing plant science

Genomic study helps to better understand the origins, history of Tibetan and Sherpa ethnic groups

Study suggests new strategy for treating arrhythmogenic cardiomyopathy

Study may help identify new sex-specific treatments for depression

Decreased viral infection severity in females linked to extra copy of epigenetic regulator

Cancer cells use new DNA repair mechanism to recover from next-generation cancer radiation therapy

Previously unknown genetic causes of three rare conditions discovered

Using a programmable control switch to deliver therapeutic RNA molecules to target cells

Novel genetics tool for mining impact assessment and biomonitoring of endangered chimpanzees

Genomic analysis shows Ashaninka people are not as homogeneous as previously reported

Researchers discover previously unknown genetic causes of three rare conditions

Potential approach to improve solid tumor T cell therapy

The impact of genome doubling on the development of cancer

Novel web-based tool deoptimizes genetic sequences based on different codon usage

Age-related sarcopenia prevented by AAV1.NT-3 gene therapy

Study evaluates the use of DNA metabarcoding to identify fish eggs

Gene that regulates cadmium distribution between leaf and grain in rice

Rice biologists embark on a three-year project to create genetically encoded antibiotics

Understanding the factors that impact CRISPRa efficiency

TurboID-based proximity labeling in meiotic cells of Arabidopsis thaliana

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Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

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Latest in Genomics