Genomics

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NEMO Protein Promotes Degradation of Harmful Alpha-Synuclein Aggregates in Parkinson's Disease

Researchers have identified a mechanism that promotes the breakdown of harmful protein deposits. If it malfunctions, it can lead to Parkinson’s disease.

21 Dec 2023

How 3D DNA Architecture Shapes Cell Fate in Early Embryos

The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another and from one organism to the next. This happens by not just simply copying the genetic information; a well-orchestrated sequence of molecular events has to happen at the right time.

21 Dec 2023

Deciphering the Structure and Function of PLD3 in Cellular Waste Disposal

If we don't take out the trash regularly, our homes become unpleasant and even a danger to our health.

21 Dec 2023

Researchers Discover Core Genes for Bacteria Colonizing Plants

Using a novel experimental approach, Max Planck researchers have discovered a core set of genes required by commensal bacteria to colonize their plant hosts.

20 Dec 2023

Unmasking the Energy Secrets of a Marine Bacterial Giant

Not all bacteria are created equal. Most are single-celled and tiny, a few ten-thousandths of a centimeter long. But bacteria of the Epulopiscium family are large enough to be seen with the naked eye and 1 million times the volume of their better-known cousins, E. coli.

19 Dec 2023

How Next-Gen Sequencing is Revolutionizing Infection Diagnosis

Scientists from Necker-Enfants Malades Hospital (AP-HP), the Institut Pasteur, Université Paris Cité, Inserm, Université Paris-Est Créteil and the Alfort National Veterinary School, coordinated by Professor Marc Eloit and Dr. Anne Jamet in collaboration with Dr. Jacques Fourgeaud and Beatrice Regnault, studied the role of global genetic characterization of samples (or non-targeted metagenomics) using next-generation sequencing (mNGS) in diagnosing infections.

19 Dec 2023

Decoding Zebrafish Development: A Comprehensive Gene Expression Atlas

Scientists from the National Institutes of Health have released a comprehensive guide to the development of zebrafish, outlining the gene expression patterns activated in almost every cell type during the initial five days of growth.

19 Dec 2023

Non-Invasive Early Cancer Detection Using Chromatin Signatures in Mononuclear Blood Cells

Blood cells reveal tumors in the body. Researchers at the Paul Scherrer Institute achieve an advance with the development of a test for early diagnosis of cancer.

18 Dec 2023

Arabidopsis thaliana’s Pioneering Role in Complete Genome Sequencing

Arabidopsis thaliana, a globally cultivated species for genetic research, achieved the milestone of being the first plant to undergo complete genome sequencing.

18 Dec 2023

Exploring the Role of Facilitators in Gene Expression

A study conducted by the Laboratory of Gene Regulation at the MRC Weatherall Institute of Molecular Medicine, headed by Professor Doug Higgs and Dr Mira Kassouf, has been published in the journal Cell.

15 Dec 2023

Innovative Machine Learning Tool Predicts Functional Consequences of Genetic Variants

In a recent research, scientists from the Icahn School of Medicine at Mount Sinai unveiled LoGoFunc, an innovative computational tool designed to forecast both pathogenic gain- and loss-of-function variants throughout the genome.

15 Dec 2023

Study Delves into the Transmission of Antimicrobial Resistance Among Cockroaches

A recent study delves into the transmission of antimicrobial resistance (AMR) among cockroaches, shedding light on potential implications for AMR transmission in humans.

15 Dec 2023

Scientists Crack the Code for Artificial DNA

The genetic code is composed of just four letters representing the four nucleotides, which are the fundamental building blocks of DNA.

14 Dec 2023

Molecular Blueprint for Understanding Brain Function

For the very first time, a global team of researchers has successfully crafted a comprehensive cell atlas for an entire mammalian brain.

14 Dec 2023

Gladstone Scientists Create Intricate Map of Human T Cell Function With Base Editing

In a study of historic scale, scientists at Gladstone Institutes have created an intricate map of how the immune system functions, examining the detailed molecular structures governing human T cells using the next-generation CRISPR tool known as base editing.

14 Dec 2023

NSF Funds IWGSC Project to Sequence Ancient Bread Wheat Genomes for Improved Traits

The International Wheat Genome Sequencing Consortium (IWGSC) is starting a two-year project, with funding from the U.S. National Science Foundation (NSF), to mine an untapped genetic resource for wheat improvement by sequencing the genomes of ancient varieties representing the worldwide diversity of bread wheat.

14 Dec 2023