Genomics

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Novel model tracks hippocampal synaptic plasticity to reveal molecular mechanisms

The accumulation of amyloid beta proteins, which encourage synaptic malfunction, causes cognitive decline in Alzheimer’s disease (AD), according to scientific evidence.

10 Mar 2023

Gaining deep insights into mezcal worms

Mezcal is a distilled alcohol made from the boiled and fermented sap of agave plants. Most mezcal beverages -; including all brands of tequila -; are sold as pure distillates, but a few have an added stowaway bottled inside: worms.

10 Mar 2023

Study identifies a novel rare mutation in gene linked to Harlequin Ichthyosis

Harlequin ichthyosis (HI) is a severe genetic skin disorder characterized by thick white, brown, or dark brown patches on the skin covering a newborn's entire body. HI has a low incidence of 1 per 300,000 live births but comes with the highest mortality rate among skin conditions. It is caused by a mutation in the ABCA12 gene, which codes for a protein involved in transporting lipids necessary for the formation of the skin barrier. Such protein shortage leads to a weaker epidermal barrier.

9 Mar 2023

“Bacterial suicide squad” recruits and activates innate and adaptive antitumor immune responses

Combining discoveries in cancer immunology with sophisticated genetic engineering, Columbia University researchers have created a sort of "bacterial suicide squad" that targets tumors, attracting the host's own immune cells to the cancer to destroy it. The new work, published today in Science Advances, marks a major step forward in efforts to enlist non-pathogenic bacteria to combat cancer.

9 Mar 2023

New gene resource for improving root systems

A strong root system allows crops to absorb water and nutrients from the soil, but scientists have little information about the genes that control root development. Recent research published in New Phytologist reveals that blocking a negative regulator gene of root development leads to enhanced root growth in plants.

8 Mar 2023

Experts sequence the faba bean genome

The faba bean genome, which at 13 billion bases is more than four times the size of the human genome, has been sequenced for the first time and is published today (08 March 2023), in Nature. This is an extraordinary technical achievement and crucial to efforts to breed beans with optimum nutritional content and sustainability of production.

8 Mar 2023

Study pinpoints a splicing deregulation that causes therapeutic vulnerability in pediatric AML

Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the adult version) that might explain its cause.

8 Mar 2023

Scientists discover mechanism behind how plants can develop long-term immunity to stress

A mechanism behind how plants can develop long-term immunity to stress has been discovered by scientists at the University of Sheffield.

8 Mar 2023

Discovery could establish an effective control environment for chromosome instability

A research team, affiliated with UNIST has unveiled a key factor involved in the DNA damage response (DDR), homologous recombination (HR) and DNA interstrand crosslink (ICL) repair.

8 Mar 2023

Socioeconomic and genetic factors likely interact in an additive way to increase risk of metabolic diseases

New research led by investigators at Massachusetts General Hospital, a founding member of Mass General Brigham, indicates that socioeconomic and genetic factors likely interact in an additive way to affect people's risks of developing obesity and type 2 diabetes.

8 Mar 2023

BGI’s fluorescent RT-PCR kit obtains market access qualification for detecting SARS-CoV-2, IFV A, IFV B in Australia

On March 2, BGI's Multiplex Real-time Fluorescent RT-PCR Kit for Detecting SARS-CoV-2, Influenza A Virus and Influenza B Virus obtained market access qualification to enter the Australian Register of Therapeutic Goods.

8 Mar 2023

An alternative option to treat ADCY5-related dyskinesia in patients

The asthma medication theophylline can be used to treat the movement disorder ADCY5-related dyskinesia. A recent study conducted by Martin Luther University Halle-Wittenberg (MLU), University Medicine Halle, and the University of Leipzig Medical Center demonstrated this.

7 Mar 2023

Using data from Sanger sequencing to quantify of genetic variants in bacterial cultures

Genetic variations, such as mutations, recombinations, or transpositions occur naturally in cultured microorganisms and are often considered nonneutral mutations.

7 Mar 2023

Quantitative method evaluates sexual conflict evolution

Males of a species that evolve sexual conflict traits can create issues for females and, eventually, the entire population.

6 Mar 2023

Significance of large-scale genetic studies in men of African ancestry

Investigators at USC’s Keck School of Medicine directed the meta-analysis, which discovered nine new genetic variants that boost the risk of prostate cancer in an under researched population, including a genetic risk score connected to aggressive forms of the disease.

6 Mar 2023

First wiring map of neurons in insect brain complete

Researchers have built the first ever map showing every single neuron and how they’re wired together in the brain of the fruit fly larva.

6 Mar 2023

Largest-ever genetic analysis provides insight into domestications and origin of traits in grapevine

In the largest ever genetic analysis of grapevine varieties, including samples from previously undocumented specimens in private collections, researchers provide new insights into how, when, and where wine and table grapevines were domesticated, which has been a longstanding question.

3 Mar 2023

Genomics

Novel model tracks hippocampal synaptic plasticity to reveal molecular mechanisms

Gaining deep insights into mezcal worms

Study identifies a novel rare mutation in gene linked to Harlequin Ichthyosis

“Bacterial suicide squad” recruits and activates innate and adaptive antitumor immune responses

New gene resource for improving root systems

Experts sequence the faba bean genome

Study pinpoints a splicing deregulation that causes therapeutic vulnerability in pediatric AML

Scientists discover mechanism behind how plants can develop long-term immunity to stress

Discovery could establish an effective control environment for chromosome instability

Socioeconomic and genetic factors likely interact in an additive way to increase risk of metabolic diseases

BGI’s fluorescent RT-PCR kit obtains market access qualification for detecting SARS-CoV-2, IFV A, IFV B in Australia

An alternative option to treat ADCY5-related dyskinesia in patients

Using data from Sanger sequencing to quantify of genetic variants in bacterial cultures

Quantitative method evaluates sexual conflict evolution

Significance of large-scale genetic studies in men of African ancestry

First wiring map of neurons in insect brain complete

Largest-ever genetic analysis provides insight into domestications and origin of traits in grapevine

New insights into the underlying mechanism that causes arrhythmogenic cardiomyopathy

Study links neutral maternal behavior toward infants with epigenetic change in children

New insights into the distribution and regulation of meiotic DSB hotspots

Expert Insights: HiMedia Labs on Advancing Nucleic Acid Extraction Across Industries

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

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