Genomics

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Study takes a deep dive into the molecular biology of the brain in bipolar disorder patients

In a comprehensive study involving one of the largest-ever samples of post-mortem brains, scientists at the Lieber Institute for Brain Development, in collaboration with researchers at the Johns Hopkins School of Medicine and Bloomberg School of Public Health, have pinpointed significant differences in gene expression in two specific regions of the brains of hundreds of patients who had bipolar disorder.

8 Mar 2022

Tweaking carotenoids found to improve plant growth and increase yield

Manipulating the content of carotenoids, such as ß-carotene, has been found to improve plant growth and increase yield and tolerance to abiotic stresses such as drought and salinity.

8 Mar 2022

Specific gene variant linked with poor response to sublingual immunotherapy for allergies

Although sublingual immunotherapy (SLIT) has become an effective treatment option for many allergies, about 20-30% of patients don’t respond to SLIT for Japanese cedar pollinosis–a highly common disease.

8 Mar 2022

Study provides insights into the biological mechanisms behind the severe form of COVID-19

A total of 16 novel genetic variations linked to severe Covid-19 have been discovered, including ones that affect blood coagulation, immunological response, and inflammation severity.

8 Mar 2022

Using Ancient DNA to Solve the Disappearance of Lions and Bears

In this interview, we speak to Dr. Alexander Salis and Dr. Kieren Mitchell about their latest research that used ancient DNA to solve the disappearance of lions and bears.

7 Mar 2022

Novel DNA test helps diagnose neurological and neuromuscular genetic diseases

The Garvan Institute of Medical Research came up with a new DNA test that helps determine a range of hard-to-diagnose neurological diseases faster.

7 Mar 2022

Multi-omics approach help researchers study the disparity created by in vitro culture

Citrus is a significant and economically beneficial horticultural crop with nucellar polyembryony, which prevents hybrid offspring from being produced. Citrus is produced mostly through asexual methods like grafting and cuttings.

7 Mar 2022

New technique controls gene activity without altering the DNA sequence of the genome

By combining CRISPR technology with a protein designed with artificial intelligence, it is possible to awaken individual dormant genes by disabling the chemical "off switches" that silence them.

7 Mar 2022

Researchers develop new method to detect the role of enigmatic gene sequences

Karolinska Institute researchers have recently developed new high-precision techniques for determining the role of these noncoding sequences.

7 Mar 2022

Researchers decode complex potato genomes to accelerate the breeding of robust varieties

Scientists have decoded the highly complicated genome of the potato for the first time after over 20 years since the first release of the human genome.

From The Max Planck Institute 7 Mar 2022

Researchers find an epigenetic adaptation showing resistance to targeted therapy in T cell leukemia

Although gene mutations can result in drug resistance, scientists in the Perelman School of Medicine at the University of Pennsylvania have found a vital, non-genetic version that could also boost resistance to targeted treatment in T cell leukemia, which is a kind of blood cell cancer.

3 Mar 2022

Study uncovers genomic drivers and therapeutic vulnerabilities of transformed cutaneous T-cell lymphoma

Cutaneous T-cell lymphoma (CTCL) is an incurable, rare cancer of skin-homing T cells that is highly disfiguring and lethal at advanced stages.

2 Mar 2022

Researchers take a big step in mapping the entirety of human genetic relationships

Scientists from the University of Oxford’s Big Data Institute have taken a big leap towards mapping the totality of genetic relationships between humans.

2 Mar 2022

Researchers discover a new epigenetic mark in small freshwater animals

Your DNA holds the blueprint to build your body, but it's a living document: Adjustments to the design can be made by epigenetic marks.

1 Mar 2022

Genetic analysis reveals markers for predicting seed oil quality in Russian sunflower

Researchers from Skoltech and Pustovoit All-Russian Research Institute of Oil Crops performed a genetic analysis of Russian sunflower lines and identified genetic markers that can help to predict the composition of tocopherols, one of the key attributes of oil quality.

1 Mar 2022

HDO technology found to be effective at silencing problematic genes

T and B lymphocytes, which are part of a group of immune cells commonly called white blood cells, work together to eliminate foreign invaders in the body such as viruses.

1 Mar 2022

Study provides first genetic evidence of demographic changes among hunter-gatherer populations

A new analysis of ancient human DNA demonstrates that people moved and chose their reproductive partners along complex social networks that stretched across large swathes of Africa between 80,000 and 20,000 years ago, according to a study co-led by Yale anthropologist Jessica Thompson.

28 Feb 2022

Scientists study the impact of genetic testing used to track unrecognized relatives

Genetic genealogy has grown in popularity in recent years, due to direct-to-consumer (DTC) genetic testing and relative-finder services provided by some DTC genetic testing companies.

28 Feb 2022

Chlamydia and HPV co-infection causes a unique cellular reprogramming, study shows

Infections with several pathogens simultaneously increase the risk of cervical cancer—these results from a study conducted on artificial 3D tissue models.

25 Feb 2022

Researchers create a regulatory map of zebrafish genome

The zebrafish is an important model organism for studying things like genetic diseases. A regulatory map of its genome has been successfully created using high-throughput experiments and AI methods, a team led by Uwe Ohler now reports in Cell Genomics and Nature Machine Intelligence.

25 Feb 2022

Genomics

Study takes a deep dive into the molecular biology of the brain in bipolar disorder patients

Tweaking carotenoids found to improve plant growth and increase yield

Specific gene variant linked with poor response to sublingual immunotherapy for allergies

Study provides insights into the biological mechanisms behind the severe form of COVID-19

Using Ancient DNA to Solve the Disappearance of Lions and Bears

Novel DNA test helps diagnose neurological and neuromuscular genetic diseases

Multi-omics approach help researchers study the disparity created by in vitro culture

New technique controls gene activity without altering the DNA sequence of the genome

Researchers develop new method to detect the role of enigmatic gene sequences

Researchers decode complex potato genomes to accelerate the breeding of robust varieties

Researchers find an epigenetic adaptation showing resistance to targeted therapy in T cell leukemia

Study uncovers genomic drivers and therapeutic vulnerabilities of transformed cutaneous T-cell lymphoma

Researchers take a big step in mapping the entirety of human genetic relationships

Researchers discover a new epigenetic mark in small freshwater animals

Genetic analysis reveals markers for predicting seed oil quality in Russian sunflower

HDO technology found to be effective at silencing problematic genes

Study provides first genetic evidence of demographic changes among hunter-gatherer populations

Scientists study the impact of genetic testing used to track unrecognized relatives

Chlamydia and HPV co-infection causes a unique cellular reprogramming, study shows

Researchers create a regulatory map of zebrafish genome

Expert Insights: HiMedia Labs on Advancing Nucleic Acid Extraction Across Industries

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

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