Molecular & Structural Biology

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Unveiling ppGpp’s Surprising Role in Fruit Fly Sleep

Sleep, a fundamental behavior observed across various organisms, ranging from worms to humans, is influenced by both internal sleep drive and external environmental factors.

12 Dec 2023

Unraveling Oxygen's Impact on Protein Dynamics

Understanding the adverse effects of insufficient oxygen becomes apparent with the simple act of holding ones breath for too long.

11 Dec 2023

Fossil Lipids and Genetics Offer Glimpse into Early Animal Diets

Paleontologists are gaining insight into life from over a billion years ago by analyzing chemical remnants in ancient rocks and studying the genetics of present-day animals.

11 Dec 2023

Brain Imaging Study Unravels the Secret of Impulse Control

A group of researchers from The University of Hong Kong and The University of Electronic Science and Technology of China has definitively pinpointed the right inferior frontal gyrus (rIFG) as a pivotal input and causal regulator within the subcortical response inhibition nodes.

11 Dec 2023

Researchers Redesign the Future of mRNA Therapeutics

Scientists have unearthed that errors in the interpretation of therapeutic mRNA by the cell’s decoding apparatus can incite an inadvertent immune reaction within the body.

7 Dec 2023

Unlocking the Mysteries of Fetal Brain Development

Cheryl Rosenfeld has dedicated three decades to investigating the transmission of biological information from mothers to babies during pregnancy.

6 Dec 2023

Molecular Docking Analysis Unlocks Secrets of Flavonoid Metabolism

In a world where plant-based lifestyles are on the rise, the power of foods such as broccoli, celery, and tofu, which are rich in flavonoids, is becoming clearer.

5 Dec 2023

Misfolded Proteins: How They Damage Neurons and Cause Neurodegeneration

Neurodegenerative diseases are characterized by the deposition of clumped proteins in the brain and progressive neuronal cell death.

5 Dec 2023

Revolutionizing Fish Immunology: A Paradigm Shift in Antibody Responses

Upon infection or immunization, antibodies, produced by all jawed vertebrates, serve to bind and neutralize pathogens.

4 Dec 2023

Unveiling the Role of the Cerebellum in Human Cognitive Evolution

The development of advanced cognitive functions in humans has primarily been associated with the growth of the neocortex, a brain region responsible for conscious thought, movement, and sensory perception.

30 Nov 2023

New Irreversible Inhibitor Overcomes Drug Resistance in Cancer Cells

The concept of irreversible inhibitors binding permanently to a target protein has garnered growing interest for potential applications in drug development.

30 Nov 2023

Deciphering the Tumor Microenvironment with Spatial Transcriptomics

Spatial transcriptomics (ST) has emerged as a crucial technique for mapping gene expression across tissue sections while preserving vital locational data, setting it apart from traditional methods like bulk or single-cell RNA sequencing.

30 Nov 2023

“Sugar” Molecule in Cells Plays Crucial Role in Disease Prevention

The body’s inherent production of a sugar-based molecule plays a crucial role in various cellular functions, including growth, differentiation into different cell types, self-destruction if necessary, and more.

29 Nov 2023

Unraveling the Molecular Basis of SIDT1 and SIDT2 in C. elegans

New work thoroughly characterizes the structural features of human SIDT1 and SIDT2, revealing their existence as dimers in vitro and their tendency to form dimers or higher-order oligomers in their natural environment.

23 Nov 2023

New Tool Tracks Mouse Movements and Brain Activity

Mice exhibit constant activity, regardless of external stimuli such as the presence of a nearby cat. Their ongoing actions, which include whisker movement, environmental exploration, and self-grooming, trigger neural responses spanning various brain regions.

21 Nov 2023