Molecular & Structural Biology

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eDNA Captured Along With Particulate Matter Reflects Local Biodiversity

The increasing loss of biodiversity and the rising incidence of species extinction is a severe threat to global ecosystems. However, measuring those losses on a global scale has been impossible, owing in large part to a lack of the necessary infrastructure.

6 Jun 2023

The Role of Noncanonical Mechanism in the Evolution of miRNA Biogenesis

The Hong Kong University of Science and Technology (HKUST) research group, guided by Prof. Tuan Anh Nguyen, Assistant Professor of the Division of Life Science, used several advanced methods, including miRNA sequencing, pri-miRNA structure analysis, and high-throughput pri-miRNA cleavage assays for approximately 260,000 pri-miRNA sequences, to locate and thoroughly illustrate the newly identified noncanonical cleavage mechanism.

6 Jun 2023

How Do Protons Move in Hachimoji DNA?

According to quantum biologists at the University of Surrey, revealing the potential of lab-crafted DNA, called synthetic DNA, holds the key to innovative breakthroughs across multiple domains.

6 Jun 2023

Online Prediction Modeling Tool to Help Advance Scientific Discoveries

By anticipating the location of proteins within a cell, researchers might have access to a trove of biological knowledge. Future scientific discoveries related to drug development and the treatment of diseases like epilepsy will depend on this information.

6 Jun 2023

New Delivery Mechanism Brings Messenger RNA to the Point of Need in Neurons

Brain cells manufacture proteins in every corner, including their long branches. Neurons missing this ability cause severe neurological disorders like disability and epilepsy.

5 Jun 2023

Fragments of RNA Viruses Discovered in Coral Partners’ Genomes

The DNA of symbiotic creatures living within reef-building corals has been found to contain the remains of ancient RNA viruses by an international team of marine researchers.

2 Jun 2023

Identifying How a Particular Riboswitch Regulates its Synthesis

Researchers across the world are in search of ways to combat bacteria that could evade the present arsenal of antibiotics. This is done as a measure to avoid a global health crisis.

2 Jun 2023

Revealing How Human Brains Encode and Retain Value-Based Information

Researchers from the Center for Cognition and Sociality (CCS) within the Institute for Basic Science (IBS) recently announced the discovery of neurons that allow us to recognize others. The research team discovered that the neurons that deal with the information associated with different individuals are located in the CA1 region of the hippocampus.

2 Jun 2023

Machine Learning-Based Tool Allows Scientists to Quickly Model Families of Proteins

Microbes drive key processes of life on Earth. They affect global elemental cycles-;the movement of carbon, nitrogen, and other elements. They also promote plant growth and affect the development of diseases. These roles are essential in every ecosystem.

2 Jun 2023

RNA Regulatory Mechanism Involving Stress Granules Directly Regulates Alzheimer’s Development

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 10, entitled, "Stress granules sequester Alzheimer's disease-associated gene transcripts and regulate disease-related neuronal proteostasis."

2 Jun 2023

Antioxidant Enzymes Relocate to the Nucleus in Response to DNA Damage

In crisis, the nucleus calls antioxidant enzymes to the rescue. The nucleus being metabolically active is a profound paradigm shift with implications for cancer research.

2 Jun 2023

Unraveling How Bivalves Evolved Among Many Others During the Cambrian Explosion

Every so often, life on Earth steps onto a nearly empty playing field and faces a spectacular opportunity.

31 May 2023

New Algorithm to Improve the Understanding of Protein Movements

Proteins are biological molecules that perform almost all biochemical tasks in all forms of life. In doing so, the tiny structures perform ultra-fast movements.

31 May 2023

Ancient DNA Reveals Earliest Evidence of Plague Cases in Britain

The Francis Crick Institute has discovered three 4,000-year-old British cases of Yersinia pestis, the bacteria that causes the plague—the oldest evidence of the plague in Britain to date. The study was published in Nature Communications.

31 May 2023

Characterizing a Pivotal Time in Mammalian Embryonic Development

Many of life’s secrets are hidden in the initial stages of embryonic development. Unraveling these mysteries can aid in the understanding of early development and birth abnormalities, as well as the creation of innovative regenerative medicine treatments.

31 May 2023

Game-Changing Research Shows Astrocytes as Key Regulators of Alzheimer's Disease Progression

Why do some people develop Alzheimer's disease while others don't? And, even more puzzlingly, why do many individuals whose brains are chock-full of toxic amyloid aggregates-;a telltale sign of Alzheimer's brain pathology-;never go on to develop Alzheimer's-associated dementias?

30 May 2023