Molecular & Structural Biology

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Researchers determine major protein complexes that cause ribosome production

Scientists at UT Southwestern have discovered a four-protein complex that seems to play a significant function in the formation of ribosomes, which serve as protein factories for cells, as well as a surprise role in neurodevelopmental diseases.

1 Apr 2022

Exceptional research recordings display RNA switching “on” and “off”

RNA switches (also known as riboswitches) control which genes are turned “on” and “off”, much like a light switch. Although this appears to be a straightforward process, biologists have been astonished by the inner workings of these switches for decades.

1 Apr 2022

Researchers discover a novel pathway for DNA transfer in the tumor microenvironment

Scientists from the University of Notre Dame have found a new way for tumor cells to transmit genetic material to other cells in their microenvironment, allowing cancer to spread.

1 Apr 2022

Multiple nanobodies effectively block infection with different SARS-CoV-2 variants

Researchers at Karolinska Institutet in Sweden have developed a novel strategy for identifying potent miniature antibodies, so-called nanobodies, against emerging SARS-CoV-2 variants.

28 Mar 2022

Minuscule involuntary eye movements are not drivers of brain signals underlying attention

Minuscule involuntary eye movements, known as microsaccades, can occur even while one is carefully staring at a fixed point in space.

28 Mar 2022

Scientists create powerful new method for generating protein drugs

A team of scientists has created a powerful new method for generating protein drugs. Using computers, they designed molecules that can target important proteins in the body, such as the insulin receptor, as well as vulnerable proteins on the surface of viruses.

28 Mar 2022

Study finds surprisingly few connections between far-reaching regions of the brain

Understanding how the brain functions, particularly how information is processed during different activities, is difficult without knowing how many axons are in the brain and how many connect different functional regions.

25 Mar 2022

Gene mutation influences autism development, study finds

A research team discovered that interruption of a circadian clock gene may be implicated in the formation of autism spectrum disorder.

25 Mar 2022

Research shows that fruit flies sperm are no more male entirely after mating

According to recent research on fruit flies, the sperm becomes half feminine after mating, which was previously thought to be purely male.

25 Mar 2022

New long-lived biological computers could potentially persist inside cells

Tiny biological computers made of DNA could revolutionize the way we diagnose and treat a slew of diseases, once the technology is fully fleshed out.

From National Institute of Standards and Technology (NIST) 24 Mar 2022

Cryo-electron microscopes help determine how “911” molecule repairs DNA damage

When something unexpected happens with DNA replication, cells call their own form of 911 to stop the process and rectify the problem.

23 Mar 2022

Scientists reveal how 9-1-1 clamp attaches to DNA damage site for initiating effective repair

DNA is often likened to a blueprint. The particular sequence of As, Cs, Gs, and Ts in DNA provides information for building an organism.

22 Mar 2022

Yale and uOttawa researchers partner to solve a puzzle rooted in the deepest past of evolution

For decades, scientists have been trying to unravel an enduring mystery of structural biology: Why do two otherwise identical protein forms found in everything from plants, amphibians and human beings hang onto a slight variation across the mighty span of evolution?

21 Mar 2022

Transcriptomic analysis of Alzheimer's patients reveals early organelle dysfunction in astrocytes

An international group of researchers led by the UAB analyzed the genes that are expressed in neurons and astrocytes based on data from 800 individuals and compared what happens in Alzheimer's patients and in people without diagnosed dementia.

21 Mar 2022

Non-steroidal anti-inflammatory drugs help to enhance crop genome editing tools, study says

According to plant scientists at RIKEN, a class of non-steroidal anti-inflammatory drugs might be useful for studying the molecular processes underlying plant immunity.

21 Mar 2022

New database provides extensive information on kinase-associated neural protein phosphorylation

Biological functions rely on accurate cellular communication involving different molecules. Most major signaling pathways involved in such communication, called signal transduction, often involve a family of kinases—enzymes catalyzing the transfer of phosphates between specific substrate molecules.

17 Mar 2022

Molecular & Structural Biology

Researchers determine major protein complexes that cause ribosome production

Exceptional research recordings display RNA switching “on” and “off”

Researchers discover a novel pathway for DNA transfer in the tumor microenvironment

Multiple nanobodies effectively block infection with different SARS-CoV-2 variants

Minuscule involuntary eye movements are not drivers of brain signals underlying attention

Scientists create powerful new method for generating protein drugs

Study finds surprisingly few connections between far-reaching regions of the brain

Gene mutation influences autism development, study finds

Research shows that fruit flies sperm are no more male entirely after mating

New long-lived biological computers could potentially persist inside cells

Cryo-electron microscopes help determine how “911” molecule repairs DNA damage

Scientists reveal how 9-1-1 clamp attaches to DNA damage site for initiating effective repair

Yale and uOttawa researchers partner to solve a puzzle rooted in the deepest past of evolution

Transcriptomic analysis of Alzheimer's patients reveals early organelle dysfunction in astrocytes

Non-steroidal anti-inflammatory drugs help to enhance crop genome editing tools, study says

New database provides extensive information on kinase-associated neural protein phosphorylation

Researchers develop an antibody as a tool for opening the blood-brain barrier

Researchers conduct a detailed study of skin layer, likely to assist in new products and treatments

Scientists use mRNA delivery to enhance muscle power

Researchers use GP2 and UMOD to prevent urinary tract infection

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