Molecular & Structural Biology

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New study investigates the stability of frozen methane crystals as the ocean temperatures rise

A vast amount of the powerful greenhouse gas is sequestered as frozen crystals in the world's oceans.

From New York University (NYU) 10 May 2022

New open-source tool automates RNA analysis, likely to encourage research and drug development

Scripps Research scientists have introduced a new software tool for examining RNA (ribonucleic acid) molecules, which play a variety of important roles in living things.

10 May 2022

Study shows how nanotechnology may help for structural research of RNA molecules

Humans live in a world created and managed by RNA—the genetic molecule DNA’s equally important sibling.

3 May 2022

The brain learns completely differently than previously assumed, researchers say

The brain is a complex network containing billions of neurons. Each of these neurons communicates simultaneously with thousands of others via their synapses (links), and collects incoming signals through several extremely long, branched "arms", called dendritic trees.

29 Apr 2022

Study shows how G protein-coupled receptors signal helps drug development

G protein-coupled receptors (GPCRs), membrane proteins that are the target of one-third of approved drugs, are being studied by scientists at St. Jude Children’s Research Hospital and Columbia University/New York State Psychiatric Institute.

29 Apr 2022

RNA binding proteins in T cells help generate an effective immune response

Two RNA binding proteins have been discovered to be the key to a greater immune reaction to influenza in mice, according to researchers at the Babraham Institute.

29 Apr 2022

Researchers analyze the potential role of mRNA in drug development and novel therapies

In latest years, messenger RNA—the DNA’s close relative in the complex process of turning a string of genetic blueprints into a properly functioning organism—has gotten a lot of attention in the scientific and medical community.

29 Apr 2022

New 3D in vitro model reveals the origins of human spine

The spinal column is the central supporting structure of the skeleton in all vertebrates. Not only does it provide a place for muscles to attach, it also protects the spinal cord and nerve roots. Defects in its development are known to cause rare hereditary diseases.

28 Apr 2022

Understanding the regulation of intramembrane proteases across the tree of life

Working with tiny bacteria, Michigan State University researchers led by Lee Kroos have made a discovery that could have big implications for biology.

27 Apr 2022

Bone growth protein may help treat newborns with rare genetic lung condition

When babies are born with alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV), their skin starts to turn blue from the under-oxygenated blood in their systems.

22 Apr 2022

Researchers discover a protein that protects the pancreas from self-digestion

The pancreas secretes around a cup of digestive juices per day—a mixture of molecules capable of breaking down the food people consume.

22 Apr 2022

Researchers explore how tRNAs evolve in protein synthesis

In the process of protein synthesis, a peptide bond is formed between two amino acids that are bound to two different transfer RNAs (tRNAs). Researchers have long been perplexed as to how these tRNAs evolved to be so near to one another on the ribosome.

From Tokyo University of Science 22 Apr 2022

Little-known protein may play a role in frontotemporal lobar degeneration

Scientists have known for years that amyloid fibrils -; fibrous, ropelike structures formed by closely linked protein molecules -; are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play a role in the progression of these disorders.

21 Apr 2022

Researchers analyze single-cell DNA sequencing for having a significant role in Alzheimer’s disease

The loss of functional neurons in the brain is a characteristic of Alzheimer’s disease. What, on the other hand, is the source of this loss?

21 Apr 2022

New protective mechanism against non-alcoholic fatty liver disease identified

Non-alcoholic fatty liver disease (NAFLD), commonly known as fatty liver disease, is a prevalent disease frequently seen in obese people. Having high fat content in the liver is detrimental as it is strongly associated with severe health problems like diabetes, high blood pressure, and liver cancer.

20 Apr 2022

Researchers may have identified a key intermediate in the transition from prokaryotes to eukaryotes

All modern organisms fall into two classes, eukaryotes and prokaryotes. Eukaryotes (from the Greek meaning "true kernel") have a cell nucleus that harbors most of the cell's genetic information and includes organisms such as humans, plants and fungi.

20 Apr 2022

Research reveals how RNA elements control cleavage activity of DICER enzyme in pre-miRNA and shRNAs

A research team led by scientists from the Hong Kong University of Science and Technology has revealed how secondary structure RNA elements control the cleavage activity of the DICER enzyme in both pre-miRNA and short-hairpin RNAs, improving the understanding of the DICER cleavage mechanism and providing a foundation for the design of accurate and efficient short-hairpin RNAs for gene-silencing.

20 Apr 2022

Molecular & Structural Biology

New study investigates the stability of frozen methane crystals as the ocean temperatures rise

New open-source tool automates RNA analysis, likely to encourage research and drug development

Study shows how nanotechnology may help for structural research of RNA molecules

The brain learns completely differently than previously assumed, researchers say

Study shows how G protein-coupled receptors signal helps drug development

RNA binding proteins in T cells help generate an effective immune response

Researchers analyze the potential role of mRNA in drug development and novel therapies

New 3D in vitro model reveals the origins of human spine

Understanding the regulation of intramembrane proteases across the tree of life

Bone growth protein may help treat newborns with rare genetic lung condition

Researchers discover a protein that protects the pancreas from self-digestion

Researchers explore how tRNAs evolve in protein synthesis

Little-known protein may play a role in frontotemporal lobar degeneration

Researchers analyze single-cell DNA sequencing for having a significant role in Alzheimer’s disease

New protective mechanism against non-alcoholic fatty liver disease identified

Researchers may have identified a key intermediate in the transition from prokaryotes to eukaryotes

Research reveals how RNA elements control cleavage activity of DICER enzyme in pre-miRNA and shRNAs

Double-stranded RNA provoke bone loss during periodontitis

Cryo-EM reveals the structure of fermentation enzyme phosphoketolase

A new breakthrough in the quest to improve photosynthesis in certain crops

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

Latest in Genomics