Overview
ioGABAergic Neurons are human induced pluripotent stem cell (iPSC)-derived GABAergic neurons, precision reprogrammed using opti-ox™ technology.
Within 12 days post-revival, ioGABAergic Neurons form a pure, defined population that is all set for experimentation, expressing (>95%) classical marker genes such as GAD1, GAD2, VGAT, DLX1, and DLX2. Calcium imaging has been utilized to illustrate that ioGABAergic Neurons display concurrent activity.
ioGABAergic Neurons are a high-quality human model that is simple to utilize for the examination of neurological circuits, neurodevelopmental and neurodegenerative disease research, and drug discovery.
Features
Quick
Quickly maturing inhibitory neurons that are all set to use within 12 days, post-revival.
Defined
More than 95% of cells express key GABAergic phenotypic markers GAD2, GAD1, VGAT, DLX1, and DLX2.
Functional
Calcium imaging illustrates that ioGABAergic Neurons display concurrent activity.
Applications
- Disease research
- Co-culture studies
- Calcium imaging
- Transcriptome analysis
- MEA analysis