ioMicroglia, the human induced pluripotent stem cell (iPSC)-derived microglia is precision reprogrammed using opti-ox™ technology. Within 10 days post-revival, ioMicroglia are all set for experimentation, expressing (>90%) key phenotypic markers, such as TMEM119, IBA1, P2RY12, CX3CR1, CD45, CD11b, and CD14.

ioMicroglia exhibits main functional traits such as phagocytosis and proinflammatory cytokine secretion and could be co-cultured with ioGlutamatergic Neurons™ with retention of phagocytic function.

ioMicroglia offers a quick, constant, functional, and user-friendly hiPSC-based model for neurodegenerative disease research and drug development.



Quickly maturing human microglia that are ready to utilize within 10 days post-revival.


ioMicroglia display main phagocytic and cytokine secretion functions.

Co-culture compatible

Appropriate for co-culture studies with neurons.


  • Drug development
  • Disease modeling
  • Co-culture studies
  • Neuroinflammation research
  • Transcriptome analysis

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