Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Deep Sea Foraminifera Species Unveil Secrets of Life in Extreme Environments

Most life on Earth relies on the sun's energy for survival, but what about organisms in the deep sea that live beyond the reach of its rays? A new study led by Woods Hole Oceanographic Institution (WHOI), published in The ISME Journal, sheds light on how a species of foraminifera, single-celled organisms found in almost all marine habitats, thrives in a dark, oxygen-free environment.

17 Jan 2025

Oxygen Sensor Protein Offers Solution for Enhancing Nitrogen Fixation in Plants

A small helper for big tasks: an oxygen sensor protein protects the enzymatic machinery of biological nitrogen fixation from serious damage.

17 Jan 2025

Researchers Develop Method to Produce Strigolactones Using Microbial Cell Factories

Sometimes just using a different tool makes the job a whole lot easier. A team of researchers co-led by the University of California San Diego has developed a method to produce a special class of plant hormones, known as strigolactones, at unprecedented levels using microbial cell factories.

17 Jan 2025

Scientists Discover Surprising Directional Flexibility in DNA-Shaping Motors

Scientists from Delft, Vienna, and Lausanne discovered that the protein machines that shape our DNA can switch direction.

17 Jan 2025

Study Unveils Surprising Cause of Brain Cell Death in Huntington's Disease

Scientists at the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells.

17 Jan 2025

Inflammasome Helps Block Malignancy in Blood Stem Cells

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, according to a preclinical study by Weill Cornell Medicine investigators.

17 Jan 2025

AI-Powered Platform for Designing Novel Protein Interactions

Researchers at EPFL have opened up a world of possibilities in the computational design of molecular interactions for biomedicine by using deep learning to create new proteins that bind to complexes involving other small molecules, such as hormones or medications.

17 Jan 2025

Researchers Develop Strategy to Boost Pharmaceutical Production in CHO Cells

An international team of researchers led by the University of California San Diego has developed a new strategy to enhance pharmaceutical production in Chinese hamster ovary (CHO) cells, which are commonly used to manufacture protein-based drugs for treating cancer, autoimmune diseases and much more.

16 Jan 2025

Study Reveals Key Ion Channel in Extracellular Vesicles for Cargo Transport

Scientists have revealed the secret to the structural integrity of tiny particles that transport cargo from cell to cell through blood vessels and bodily fluids: special proteins that keep their membranes intact as they negotiate shifting electrical impulses in different biological environments.

16 Jan 2025

Breakthrough in Understanding Semliki Forest Virus Neuro-Invasion

In a recent study, researchers from Uppsala University show that the Semliki Forest virus enters the central nervous system by first entering the cerebrospinal fluid and then binding to a specific cell type before penetrating deeper into the brain.

16 Jan 2025

Protein Shapes Reveal Deeper Evolutionary Relationships

According to a study published in the journal Nature Communications, the three-dimensional form of a protein can be utilized to determine long-standing evolutionary relationships in the tree of life.

16 Jan 2025

New Study Offers Hope for Safer, More Effective Snakebite Treatment

Last year’s Chemistry Nobel Laureate published a new study in Nature that could revolutionize the way snakebite is treated.

16 Jan 2025

Is Calcium Signaling the Bridge Between Unicellular and Multicellular Life?

Calcium-dependent signaling in S. rosetta uncovers mechanisms of cellular coordination, shedding light on the evolution of multicellularity and sensory systems.

16 Jan 2025

Compound from Sea Sponge Could be Used as a Chemical Probe for Research

Girolline, a compound extracted from the sea sponge Pseudaxinyssa cantharella, has been investigated for possible antitumor effects and also found to have anti-malarial effects.

15 Jan 2025

Study Reveals How Gut Bacteria and the Body Regulate Bile Acids

Our gut is a bustling hub of activity, home to trillions of microbes that work together with our bodies to keep us healthy.

15 Jan 2025

Genetic Analysis Sheds Light on How Staphylococcus aureus Evades the Immune System

The most detailed study to date on the mechanisms by which a common type of bacterium, Staphylococcus aureus, adapts to living on the human body could help improve the prevention, diagnosis, and treatment of certain infections.

15 Jan 2025

New Genetic Risk Factor Identified for SARS-CoV-2 Infection

Researchers have identified a novel genetic risk factor for SARS-CoV-2 infection, providing new insights into the virus' ability to invade human cells. SARS-CoV-2 is the virus that spreads COVID-19.

15 Jan 2025

Base Editing Technique Extends Lifespan in Prion Disease Mouse Model

Researchers at the Broad Institute of MIT and Harvard have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition.

15 Jan 2025

Understanding RapA's Function in E. coli R-loop Control

From a genetic perspective, it is the worst-case scenario for a bacterium: during transcription, freshly created RNA adheres to its DNA template to form a three-stranded structure called an R-loop.

15 Jan 2025

Exploring the Therapeutic Potential of Copper Against Bacteria

A researcher at the University of Arizona College of Medicine in Tucson was awarded a $1.9 million grant by the National Institutes of Health to carry out more research on the mysteries of copper, particularly how it can be used to eradicate dangerous bacteria and other microorganisms.

13 Jan 2025