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Autophagy: A Double-Edged Sword in Cancer and Protein Conformational Disorders

A new FEBS Letters review explores the dual role of autophagy in cancer and protein misfolding diseases—highlighting its potential as a therapeutic target and the challenges of tipping the balance between protection and harm.

20 May 2025

Environmental Nanoplastics Linked to Increased Foodborne Virus Severity

There are nanoplastics everywhere. These particles are found in water, food, and bodies; they are so small that they can build up on bacteria and be absorbed by plant roots.

20 May 2025

Trace the Evolution of Malaria Parasite Proteins

Researchers at the Francis Crick Institute and the Gulbenkian Institute for Molecular Medicine (GIMM) have discovered that the evolution of a family of exported proteins in the malaria-causing parasite Plasmodium falciparum allowed it to infect people.

20 May 2025

How LEM-3 Cleaves DNA Bridges During Cell Division Revealed

If DNA bridges remain between chromosomes after cell division, chromosomes become improperly segregated, resulting in genetic instability and cancer.

20 May 2025

Animal Brains are a Treasure Trove of Innovation

A Monash University researcher at the forefront of animal cognition and behavioral studies is shining a light on how the field plays a critical role in driving forward societal innovation.

20 May 2025

Microalgae Offer Eco Friendly Approach to Antibiotic Removal

Microalgae of the species Monoraphidium contortum have the ability to remove antibiotic residues from water, especially sulfamethoxazole and trimethoprim.

19 May 2025

Study Resolves Longstanding Mystery of Ashwell-Morell Receptor

Study applies new techniques to reexamine a receptor linked to sepsis and resolve contradictions regarding its binding interactions with other proteins.

19 May 2025

Liver Energy Storage Tied to Genetic Activity in PPP1R3B

A new study published in Science Advances reveals that a single gene plays a big role in how the liver stores energy, a process that's critical for overall health and for managing diseases like type 2 diabetes.

19 May 2025

Addressing Protein Leakage in Cells to Improve the Accuracy of Single-Cell Proteomic Data

A new study in Nature Communications presents a solution to protein leakage in single-cell proteomics, improving data quality by identifying and excluding permeabilized cells using a machine learning classifier.

19 May 2025

Novel Bacterial Immune Weapon that Starves Viral Invaders

The discovery of Cat1 reveals how CARF effectors use complex structures to inhibit viral replication, advancing our understanding of bacterial immune responses.

19 May 2025

Molecular Mechanism Revealed by Stop-Motion Electron Microscopy

Using electron microscopy, researchers illustrate FusB's role in antibiotic resistance, providing a molecular-level understanding of fusidic acid interactions.

19 May 2025

Decoding a 3-Billion-Year-Old Cyanobacterial Nanodevice

Scientists unveil the structure of a light-harvesting nanodevice in ancient cyanobacteria, revealing insights into early oxygen-producing photosynthesis.

19 May 2025

Fitness Fight: Native Bees Struggle Against Invasive Honey Bee

New Curtin University research has revealed that high densities of European honey bees could be harming Australian native bees’ ‘fitness’ by reducing their reproductive success and altering key traits linked to survival.

19 May 2025

Understanding Particle Drift and its Influence on Oral Drug Absorption Using Flux Tools

Explore how particle drift influences oral drug absorption and why flux tools are essential for accurate assessment.

From Pion Inc 19 May 2025

SWEET13 Gene Unlocks Sugar Accumulation in Sorghum Grains

Sorghum millet is seen as the crop plant of the future: It builds up a particularly high amount of biomass and thrives in harsh conditions.

17 May 2025

Single Cell Sequencing Uncovers Hidden Drivers of Severe Celiac Disease

Scientists have identified mutated immune cell clones that could point to improved treatment for refractory celiac disease.

17 May 2025

Carriers of Recessive Disorders Face Hidden Health and Reproductive Problems

As a group, carriers of recessive disorders are slightly less healthy and have a reduced chance of having offspring.

16 May 2025

Breakthrough Study Identifies Unique Breast Cancer Genes in South African Women

Genetic factors contribute to some 30% of breast cancer cases in SA, necessitating investment in genomic research in African contexts.

16 May 2025

New 3D Stem Cell Model Mimics Human Amniotic Sac Development

Researchers at the Francis Crick Institute have developed a new stem cell model of the mature human amniotic sac, which replicates development of the tissues supporting the embryo from two to four weeks after fertilization.

16 May 2025

Scientists Develop EvoCAST for Efficient and Accurate Gene Insertion

Ask scientists what gene editing tool is most needed to advance gene therapy, and they'd probably describe a system that's now close to realization in the labs of Samuel Sternberg at Columbia University Vagelos College of Physicians and Surgeons and David Liu at the Broad Institute of MIT and Harvard.

16 May 2025