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A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.

New Synthetic Biology Tool Improves Genetic Circuit Integration and Functionality

The research team led by Professor Jongmin Kim from the Department of Life Sciences at POSTECH, along with graduate students Hyunseop Goh and Seungdo Choi, has successfully developed the 'Synthetic Translational Coupling Element (SynTCE),' significantly enhancing the precision and integration density of genetic circuits in synthetic biology.

23 Dec 2024

Discovery of ALAS1's Secret Role Could Boost Cancer Therapy Development

In everyday life, when things turn out the opposite of what you expect, it's usually cause for frustration. In science, it's often the starting point for discovery.

23 Dec 2024

PlantRNA-FM: Bridging the Gap Between RNA Structure and Function

With PlantRNA-FM, researchers can systematically analyze plant RNA, uncovering functional motifs that play key roles in gene expression and stress responses.

23 Dec 2024

New Genetic Link to Autism Identified

New research published in The American Journal of Human Genetics has identified a previously unknown genetic link to autism spectrum disorder (ASD). The study found that variants in the DDX53 gene contribute to ASD, providing new insights into the genetic underpinnings of the condition.

20 Dec 2024

Engineering Yeast Promoters for Biologic Manufacturing

When introducing genes into yeast to make it produce drugs and other useful substances, it is also necessary to reliably switch the production on or off. A Kobe University team found three gene regulation design principles that provide a flexible guideline for the effective control of microbiological production.

19 Dec 2024

Neural Stem Cells Found to Rejuvenate the Aging Brain

Much like plants in a thriving forest, certain cells in the brain create a nurturing environment, enhancing the health and resilience of their neighbors, while others promote stress and damage, akin to a noxious weed in an ecosystem.

19 Dec 2024

Space Experiment Reveals Surprising Brain Cell Behavior

Microgravity exposure accelerates brain cell development in organoids, revealing potential implications for neurodegenerative disease research and space health.

18 Dec 2024

New Strategy to Combat Antibiotic-Resistant Bacteria

The discovery of a vulnerability in antibiotic resistance mechanisms may lead to improved strategies for combating superbugs and enhancing current therapies.

18 Dec 2024

A revolutionary antibody approach to fight cancer by restoring cellular fitness

Ovarian cancer cells exploit cell competition by altering Flower protein isoforms in stromal cells, promoting tumor survival and potential therapeutic targets.

18 Dec 2024

Single-Cell RNA Sequencing Sheds Light on Craniopharyngioma Tumor Subtypes

Craniopharyngiomas are brain tumors that negatively impact the hormonal function of the nearby pituitary.

17 Dec 2024

BOOSTER Gene: Unlocking New Potential in Photosynthesis and Crop Productivity

The BOOSTER gene enhances photosynthesis in plants, improving efficiency and productivity under varying light conditions, crucial for agricultural advancements.

17 Dec 2024

New Method for Discovering Antibiotics from Bacteria

Numerous natural products produced by microorganisms can be utilized as active ingredients to treat illnesses like cancer and infections.

16 Dec 2024

Targeting Cancer with Nanoparticle-Delivered Gene Therapy

Scientists are literally shining a laser on the energy centers of cancer cells in an attempt to harm these sources of power and cause widespread cancer cell death.

16 Dec 2024

Researchers Uncover Lamin A's Role in DNA Repair and Premature Aging Disease

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have discovered how a protein called lamin A helps repair the protective barrier around a cell's DNA.

16 Dec 2024

Scientists Discover New Twist in DNA Looping Mechanism

Scientists from the Kavli Institute of Delft University of Technology and the IMP Vienna Biocenter discovered a new property of the molecular motors that shape our chromosomes.

16 Dec 2024

New Genetic Insights into Craniofacial Defects and Embryonic Development

An international team of researchers has identified a key genetic mechanism that regulates the formation and migration of cranial neural crest cells, which are essential for developing facial structures.

16 Dec 2024

Ancient DNA Reveals Neandertal Gene Flow into Modern Humans

Ancient DNA research suggests that our non-African ancestors mixed with Neandertals about 50,000 years ago, resulting in one to two percent Neandertal DNA in non-African modern humans.

14 Dec 2024

New iFlpMosaics Toolkit Enhances Gene Research and Disease Insights

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has developed a comprehensive set of innovative genetic tools and mouse lines, called iFlpMosaics, designed to enhance the study of gene function and its implications in health and disease.

14 Dec 2024

A breakthrough in muscle cell regeneration and alignment with ultrasonic vibrations.

This study explores the use of ultrasonication to align and enhance the differentiation of myotubes, providing a non-invasive, scalable approach for tissue engineering and regenerative medicine.

13 Dec 2024

Study Reveals Genetic Basis of Sweetpotato Flesh Color Regulation

Sweetpotatoes are an agricultural powerhouse that feeds millions globally. However, their complex genetics make it challenging for breeders to understand and improve traits like yield, disease resistance, and nutritional content. A new study reveals insights into the significance of leveraging "allele dosages" in sweetpotato breeding practices.

13 Dec 2024