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Novel Cellular Atlas of the Human Gastrointestinal Tract

Spatial and single-cell data from 1.6 million cells have been combined to produce the most complete cell map of the human stomach to date.

21 Nov 2024

Cancer-Causing Mutations Found in Healthy Breast Tissue

Williams, M. J., et al. (2024) Luminal breast epithelial cells of BRCA1 or BRCA2 mutation carriers and noncarriers harbor common breast cancer copy number alterations. Nature Genetics. doi.org/10.1038/s41588-024-01988-0.

21 Nov 2024

The Role of Social Networks in Shaping Gut Microbiome Diversity

In addition to having comparable interests, preferences, lifestyles, and other characteristics, friends can also have similar gut microbial compositions, according to a recent study led by Yale University.

21 Nov 2024

Study Reveals Mystery Behind Extra Genes in Coronaviruses

Viruses are lean, mean, infection machines. Their genomes are tiny, usually limited to a handful of absolutely essential genes, and they shed extra genomic deadweight extremely fast.

20 Nov 2024

Scientists Use Cell Density to Control Tissue Formation

Genes aren't the sole driver instructing cells to build multicellular structures, tissues, and organs.

20 Nov 2024

How CRISPRi is Helping Combat Drug-Resistant Tuberculosis

Findings on isoniazid-resistant M. tuberculosis reveal key vulnerabilities, suggesting new avenues for treatment strategies against drug-resistant tuberculosis.

20 Nov 2024

Advanced Sequencing Uncovers Cause of Rare Mitochondrial Encephalopathy

Mitochondrial diseases are among the most prevalent hereditary metabolic disorders, known to occur in one out every 5000 births.

19 Nov 2024

Magnesium-Focused Approach to Curbing Antibiotic Resistance

According to recent estimates, the number of fatal antibiotic-resistant illnesses is expected to increase significantly over the next 25 years.

18 Nov 2024

Study Shows How Genetic Variations Can Enhance Cancer Drug Effectiveness

By exploiting the genetic variation in cancer cells, an already approved cancer drug demonstrated enhanced effects against cancer cells in specific patient groups.

15 Nov 2024

AI Tool Predicts Gene Activity from Tumor Images to Guide Treatment

To determine the type and severity of a cancer, pathologists typically analyze thin slices of a tumor biopsy under a microscope.

15 Nov 2024

Researchers Uncover Valuable Genetic Diversity in Barley Pangenome

Reliable crop yields fueled the rise of human civilizations. As people embraced a new way of life, cultivated plants, too, had to adapt to the needs of their domesticators.

14 Nov 2024

Engineering Cyanobacteria for Enhanced Ethanol Production

Researchers are investigating the creation of biofuel from microorganisms as a result of the increased need for sustainable fuel alternatives worldwide.

13 Nov 2024

Researchers Provide Genetic Diagnosis for 30 Long-Term Undiagnosed Cases

An international team of researchers has provided a genetic diagnosis for 30 individuals whose condition was undiagnosed for years despite extensive clinical or genetic testing.

11 Nov 2024

Using Machine Learning to Understand Gene Interactions

By examining changes in gene expression, researchers gain insights into how cells operate at a molecular level, which can contribute to a better understanding of the onset of various diseases.

8 Nov 2024

CRISPR Reveals Hidden Functions of Noncoding RNA

Genes contain instructions for protein production, with the central dogma of biology stating that this information flows from DNA to RNA to proteins.

8 Nov 2024

UAB Develops a Polygenic Score to Predict Cancer Drug Resistance

In 1937, President Franklin Roosevelt signed the National Cancer Act, launching a nationwide effort to combat the disease.

8 Nov 2024

Genetic Analysis Redefines Stories of Pompeii Victims

A new genetic study demands reexamination of the identities of, and relationships among, some of the people buried and preserved in the ancient Roman city of Pompeii.

8 Nov 2024

New GIFT Method Outshines GWAS in Genetic Breakthrough

Genomic Informational Field Theory (GIFT) enhances genetic association detection, outperforming GWAS in mapping complex traits and subtle genetic interactions.

8 Nov 2024

New Understanding of the Evolution of Multicellular Life

In 2017, the single-celled species Chromosphaera perkinsii was found in maritime sediments in Hawaii. More than a billion years ago, long before the first animals appeared on Earth, the earliest indications of its existence were found.

7 Nov 2024

Scientists Discover a Hidden Ally in the Fight Against Cancer

An intracellular sensor that tracks the quality of so-called MHC-I molecules which aid the immune system in identifying and eliminating dangerous cells, including tumor cells has been discovered by a global team headed by Goethe University Frankfurt.

7 Nov 2024