Bioengineering News and Research

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Temperature-Sensitive Protein Enables Non-Invasive Control of Cellular Behavior

Imagine being at a big marquee event at an arena, like the Super Bowl, with the roar of the crowd, the smell of hot dogs, and a sea of jerseys all merging into one chaotic blur.

30 Jan 2025

New Method for Engineering GPCRs Opens Pathways for Advanced Drug Development

Proteins are life's engines, powering processes like muscle movement, vision, and chemical reactions.

24 Jan 2025

Bacterial Growth in Mucus Leads to Formation of Cable-Like Structures

Scientists at Caltech and Princeton University have discovered that bacterial cells growing in a solution of polymers, such as mucus, form long cables that buckle and twist on each other, building a kind of "living Jell-O."

20 Jan 2025

New Approach Aims to Make CRISPR Therapy Safer and More Effective

CRISPR is a powerful gene-editing tool that holds enormous potential for treating genetic diseases by allowing scientists to cut, replace, or delete mutations in DNA.

16 Jan 2025

Researchers Develop Strategy to Boost Pharmaceutical Production in CHO Cells

An international team of researchers led by the University of California San Diego has developed a new strategy to enhance pharmaceutical production in Chinese hamster ovary (CHO) cells, which are commonly used to manufacture protein-based drugs for treating cancer, autoimmune diseases and much more.

16 Jan 2025

Researchers Develop Method to Visualize Nanocarriers at Single-Cell Level

How can we ensure that life-saving drugs or genetic therapies reach their intended target cells without causing harmful side effects? Researchers at Helmholtz Munich, Ludwig-Maximilians-Universität (LMU) and Technical University Munich (TUM) have taken an important step to answer this question.

16 Jan 2025

Study Reveals Key Ion Channel in Extracellular Vesicles for Cargo Transport

Scientists have revealed the secret to the structural integrity of tiny particles that transport cargo from cell to cell through blood vessels and bodily fluids: special proteins that keep their membranes intact as they negotiate shifting electrical impulses in different biological environments.

16 Jan 2025

New Study Offers Hope for Safer, More Effective Snakebite Treatment

Last year’s Chemistry Nobel Laureate published a new study in Nature that could revolutionize the way snakebite is treated.

16 Jan 2025

New Gene Editing Tool Combines Multiple Functions for Treating Genetic Diseases

Influential inventions often combine existing tools in new ways. The iPhone, for instance, amalgamated the telephone, web browser and camera, among many other devices.

9 Jan 2025

Next-gen ‘smart cells’ take a major step forward

A new building kit for creating unique sense-and-respond circuits in human cells has been created by bioengineers at Rice University.

6 Jan 2025

Breakthrough in Nanopore Technology Could Transform Disease Detection

UC Riverside scientists have developed a nanopore-based tool that could help diagnose illnesses much faster and with greater precision than current tests allow, by capturing signals from individual molecules.

3 Jan 2025

New Gene Editing Tool Targets Alzheimer's by Skipping Disease-Causing Gene Segments

A new gene editing tool that helps cellular machinery skip parts of genes responsible for diseases has been applied to reduce the formation of amyloid-beta plaque precursors in a mouse model of Alzheimer's disease, researchers at the University of Illinois Urbana-Champaign report.

24 Dec 2024

Engineering Yeast Promoters for Biologic Manufacturing

When introducing genes into yeast to make it produce drugs and other useful substances, it is also necessary to reliably switch the production on or off. A Kobe University team found three gene regulation design principles that provide a flexible guideline for the effective control of microbiological production.

19 Dec 2024

New Strategy to Combat Antibiotic-Resistant Bacteria

The discovery of a vulnerability in antibiotic resistance mechanisms may lead to improved strategies for combating superbugs and enhancing current therapies.

18 Dec 2024

AI Creates the First Virtual Human Cell

A team of scientists from Stanford University, Genentech, and the Chan-Zuckerberg Initiative claims that science has an “unprecedented opportunity” to use artificial intelligence (AI) to create the first virtual human cell in history, pointing out that recent advancements in AI and the availability of extensive experimental data about human biology have reached a critical mass.

13 Dec 2024