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A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.

DNA Cassettes Enable Long-Lasting Antibody Production Directly Inside Patients

A multidisciplinary team of scientists led by The Wistar Institute, including Perelman School of Medicine at the University of Pennsylvania, AstraZeneca and Inovio Pharmaceuticals, published today in Nature Medicine a breakthrough in biologic antibody production that happens directly in human subjects in this encouraging first clinical trial of its kind.

23 Oct 2025

Research Pinpoints HMGN1 as Cause of Trisomy 21-Related Heart Abnormalities

Three copies of chromosome 21 causes Down syndrome (DS), and roughly half of children born each year in the United States with DS-approximately 2,600-also have congenital heart defects (CHDs).

23 Oct 2025

Biological Bulldozer Mechanism Explains Ants’ Powerful Sense of Smell

Ants have evolved an acute sense of smell, which requires each sensory neuron to choose one scent receptor out of hundreds.

23 Oct 2025

Mapping the Molecular Choreography of Nuclear Pore Transport

Nuclear pore complexes (NPCs) are tiny but sophisticated gatekeepers that control the flow of materials between a cell's nucleus and its cytoplasm by quickly selecting which molecules to transport across the nuclear membrane.

22 Oct 2025

Cracking the Code of T Cell Expansion Inside Tumors

The ability of immune cells-particularly CD8+ T cells-to launch a rapid burst of proliferation inside tumors is key to the success of modern day cancer immunotherapies.

22 Oct 2025

Disarming Cancer’s Droplet Hubs to Halt Tumor Growth

In a city, coworking hubs bring people and ideas together. Inside cancer cells, similar hubs form-but instead of fueling progress, they supercharge disease. That's what researchers at the Texas A&M University Health Science Center (Texas A&M Health) have discovered inside the cells of a rare and aggressive kidney cancer.

21 Oct 2025

Decoding the Genetic Network Behind Soybean Shade Tolerance

In intercropping systems, soybeans grown beneath tall maize plants experience severe shading that disrupts photosynthesis, weakens stems, and limits yield.

21 Oct 2025

Synthetic Biology Unlocks New Ways to Engineer Plant–Microbe Interactions

By integrating engineering principles with plant biology, this review highlights how redesigned genetic pathways and plant-based biosensors can deepen understanding of plant responses to both harmful and beneficial microbes.

17 Oct 2025

Cancer Reawakens Embryonic Gene Editors to Fuel Tumor Growth

Cancer cells are known to reawaken embryonic genes to grow. A new study reveals the disease also hijacks the proteins, or "editors", that control how those genes are read.

17 Oct 2025

Molecular Brake SlKNU Regulates Flower Formation and Fruit Development in Tomato

Floral meristems (FMs) are small clusters of stem cells that orchestrate flower formation and ultimately determine the size and structure of the fruit.

17 Oct 2025

Research Reveals Transcriptional Mechanism Behind Salt Tolerance in Watermelon

High soil salinity disrupts water absorption, ion balance, and photosynthesis in plants, leading to growth inhibition and yield loss.

16 Oct 2025

Longevity Gene from Centenarians Reverses Heart Damage in Rare Genetic Disorder

A new breakthrough in a rare genetic disease which causes children to age rapidly has been discovered using 'longevity genes' found in people who live exceptionally long lives - over 100 years old.

16 Oct 2025

Combating Influenza A Virus with CRISPR and Human Lung Organ Chips

The Influenza A virus (IAV) has been the cause of six major flu pandemics, responsible for 50 to 100 million deaths globally.

16 Oct 2025

Biological Effects of Childhood Abuse Uncovered Through Epigenome-Wide Analysis

Child maltreatment, which includes abuse and neglect, is one of the most serious public health concerns worldwide.

16 Oct 2025

Cellular Switches Direct Supplies During Memory Formation

When we form a memory, brain cells need to deliver supplies to strengthen specific neural connections.

15 Oct 2025

Revolutionary Technique Produces Trillions of Healthy Endothelial Cells

Scientists have discovered a method to induce human endothelial cells from a small biopsy sample to multiply in the laboratory, producing more than enough cells to replace damaged blood vessels or nourish organs for transplantation, according to a preclinical study by Weill Cornell Medicine investigators.

15 Oct 2025