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Study reveals molecular details of how SARS-CoV-2 infects cells

The molecular details of how SARS-CoV-2 enters cells and infects them are still not clear. Researchers at Uppsala University have tested the bioinformatic predictions made by another research group and have identified receptors that could be important players in the process.

9 Feb 2021

Continuous in vitro monitoring could lead to faster, more effective treatments for chronic conditions

A world-first discovery by researchers at Monash University and The University of Queensland could lead to faster and more effective treatments for chronic health complications, such as cardiovascular disease and cancer, with 'fluorescent' in vivo biosensors.

27 Jan 2021

New approach to biomaterial production may ease environmental burden of forestry, agriculture

It takes a lot to make a wooden table. Grow a tree, cut it down, transport it, mill it ... you get the point. It's a decades-long process. Luis Fernando Velásquez-García suggests a simpler solution: "If you want a table, then you should just grow a table."

22 Jan 2021

Study identifies new mode of male endocrine disruption due to environmental arsenic exposure

Arsenic exists ubiquitously in an organic or inorganic state in the environment. General populations are commonly exposed to arsenic by digestion.

21 Jan 2021

Study shows how specific gene mutations cause different types of diseases

Renowned cancer experts have resolved a query of how different types of mutations in a single gene are responsible for causing various types of diseases.

15 Jan 2021

Protein phosphatase inhibition could contribute to the treatment of cancer, other diseases

The abundant presence of an enzyme known as low molecular weight protein tyrosine phosphatase (LMWPTP) in tumor cells has long been considered an indicator of cancer aggressiveness and metastatic potential.

13 Jan 2021

New model can help identify potential drug targets for ulcerative colitis

Scientists from the Lerner Research Institute at Cleveland Clinic have designed an innovative, patient-derived model of ulcerative colitis that will help scale up studies into new therapies for chronic inflammatory bowel disease.

12 Jan 2021

Kobe University and Sysmex conduct joint research on new blood test for identifying COVID-19

Kobe University and Sysmex Corporation have been engaged in joint research on the ELISPOT method, a new blood test for identifying the novel coronavirus disease (COVID-19).

28 Dec 2020

Scientists discover new class of compounds for combating antimicrobial resistance

Wistar Institute scientists have discovered a new class of compounds that uniquely combine direct antibiotic killing of pan drug-resistant bacterial pathogens with a simultaneous rapid immune response for combatting antimicrobial resistance (AMR). These finding were published today in Nature.

24 Dec 2020

Researchers discover protein that may trigger lung scarring

Systemic sclerosis is an autoimmune disease associated with inflammation and fibrosis, or scarring, that affects organs including the skin, heart, kidney and lungs.

18 Dec 2020

Fibrous protein could lead to more efficient bioprinting, tissue engineering applications

Fibrous proteins such as collagen and fibrinogen form a thin solid layer on the surface of an aqueous solution similar to the "skin" that forms on warm milk, according to a team of Penn State Researchers, who believe this finding could lead to more efficient bioprinting and tissue engineering.

18 Dec 2020

Mouse stem cells converted into oocyte-like cells by just eight genes

Researchers have demonstrated that activating eight genes is enough to induce the stem cells of mice to transform into oocyte-like cells that can be fertilized.

17 Dec 2020

Newly identified diagnostic marker can help overcome treatment resistance in cervical cancer

Scientists from the University of California, Los Angeles have discovered a promising diagnostic marker that may help predict the response of cervical cancer patients to standard radiation and chemotherapy treatments.

14 Dec 2020

Study elucidates genes responsible for Glioblastoma invasiveness

One of the hallmarks of Glioblastoma (GBM), the most aggressive type of brain cancer, is its high invasive capacity, which leads to its expansion into the normal brain tissue.

14 Dec 2020

New model helps assess the effect of epigenetic changes on gene expression

Researchers have developed a mathematical model to quantitatively assess the impacts of particular epigenetic changes on the transcription rates.

11 Dec 2020

Newly identified Cas9 nucleases can improve genome editing

Scientists have explained two new compact Cas9 nucleases that will possibly extend the Cas9 toolbox for genome editing.

11 Dec 2020

Mice infused with CD5-deleted CAR T cells showed significant reduction in tumor size

Knocking out a protein known to stifle T cell activation on CAR T cells using the CRISPR/Cas9 technology enhanced the engineered T cells' ability to eliminate blood cancers, according to new preclinical data from researchers in the Perelman School of Medicine at the University of Pennsylvania and Penn's Abramson Cancer Center.

8 Dec 2020

Drug meant for bacterial infections can combat weight gain

A drug originally developed to treat bacterial infections has proved capable of boosting the metabolism and attenuating the weight gain induced by a fatty diet in tests with mice. The study was conducted at the University of Campinas (UNICAMP) with FAPESP's support, and the findings have just been published in the journal Science Advances.

3 Dec 2020

Plant amyloids could improve nutritional value of plant seeds, reduce allergenicity of legume seeds

Thanks to this work, as the journal Trends in Plant Science recently noted, it is now known that functional amyloids serve biological functions in representatives of almost all large groups of living organisms: bacteria, archaea, animals, fungi, and plants.

3 Dec 2020

Chemical compounds in foods can inhibit a key SARS-Cov-2 enzyme

Chemical compounds in foods or beverages like green tea and dark chocolate can bind to and block the function of an enzyme in SARS-CoV-2.

3 Dec 2020

in vitro News and Research

Study reveals molecular details of how SARS-CoV-2 infects cells

Continuous in vitro monitoring could lead to faster, more effective treatments for chronic conditions

New approach to biomaterial production may ease environmental burden of forestry, agriculture

Study identifies new mode of male endocrine disruption due to environmental arsenic exposure

Study shows how specific gene mutations cause different types of diseases

Protein phosphatase inhibition could contribute to the treatment of cancer, other diseases

New model can help identify potential drug targets for ulcerative colitis

Kobe University and Sysmex conduct joint research on new blood test for identifying COVID-19

Scientists discover new class of compounds for combating antimicrobial resistance

Researchers discover protein that may trigger lung scarring

Fibrous protein could lead to more efficient bioprinting, tissue engineering applications

Mouse stem cells converted into oocyte-like cells by just eight genes

Newly identified diagnostic marker can help overcome treatment resistance in cervical cancer

Study elucidates genes responsible for Glioblastoma invasiveness

New model helps assess the effect of epigenetic changes on gene expression

Newly identified Cas9 nucleases can improve genome editing

Mice infused with CD5-deleted CAR T cells showed significant reduction in tumor size

Drug meant for bacterial infections can combat weight gain

Plant amyloids could improve nutritional value of plant seeds, reduce allergenicity of legume seeds

Chemical compounds in foods can inhibit a key SARS-Cov-2 enzyme

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