Cancer News and Research

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Cancer begins in your cells, which are the building blocks of your body. Normally, your body forms new cells as you need them, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor. Tumors can be benign or malignant. Benign tumors aren't cancer while malignant ones are. Cells from malignant tumors can invade nearby tissues. They can also break away and spread to other parts of the body.

Human Pangenome Research Opens a New Chapter in Precision Medicine

In May 2023, the Human Pangenome Reference Consortium (HPRC) released the first draft of the human pangenome reference sequence, which integrated genomic data from 47 individuals representing genetic diversity and added 119 million base pairs of euchromatic polymorphic sequences.

10 Nov 2025

St. Jude Scientists Discover Hidden Binding Pocket in Nuclear Receptors

A study from St. Jude Children's Research Hospital uncovered an alternative binding pocket within nuclear receptors, revealing a much-needed new therapy route for this important class of drug targets.

7 Nov 2025

Comprehensive Kinase Atlas Redefines Regulation of Gene Transcription Machinery

The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme's "tail" called phosphorylation patterns.

7 Nov 2025

Scientists Reveal Nonenzymatic Role of NUDT5 in Purine Pathway Regulation

Inside every cell, a finely tuned metabolic network determines when to build, recycle, or stop producing essential molecules.

7 Nov 2025

Using AI and "Protein Language" Models to Speed Monoclonal Antibody Design

Artificial intelligence (AI) and "protein language" models can speed the design of monoclonal antibodies that prevent or reduce the severity of potentially life-threatening viral infections, according to a multi-institutional study led by researchers at Vanderbilt University Medical Center.

6 Nov 2025

Two Genetic Mapping Approaches Reveal Distinct Sides of Disease Biology

The two main approaches for discovering disease genes reveal distinct aspects of biology, a new study shows.

6 Nov 2025

Ferroptosis Suppression Identified as a Key Driver of Lung Cancer Growth

NYU Langone Health researchers found that a type of cell death caused by a buildup of highly reactive molecules suppresses lung tumor growth.

6 Nov 2025

New Genomic Method Unlocks Diagnoses for Rare Conditions

A new genomic method has enabled multiple people with rare conditions to receive diagnoses that were previously unattainable by identifying complex structural genetic changes that are often missed by standard tests.

4 Nov 2025

Weill Cornell Scientists Develop Safe and Precise Tool to Control Gene Activity

Investigators at Weill Cornell Medicine have developed a versatile and non-toxic technology for controlling the activity of any gene in a cell. Such "gene-switch" tools allow scientists to "turn on" or "turn off" a target gene to study how it works, model diseases and design new therapies.

4 Nov 2025

TUM Researchers Discover Molecular Switch Controlling Programmed Cell Death

In the fight against disease, programmed cell death – also known as apoptosis – is a key protective function of the body.

4 Nov 2025

Study Reveals Shared Genetic Roots Between ALS and Hereditary Spastic Paraplegia

Motor neuron diseases, such as amyotrophic lateral sclerosis (ALS) and hereditary spastic paraplegia (HSP), share physical similarities but have been largely viewed as genetically distinct.

3 Nov 2025

Researchers Use Bacterium’s Own Defenses to Amplify Antibiotic Power

Scientists at St. Jude Children's Research Hospital have found a way to use a bacterium's own drug resistance mechanisms against itself, presenting a potentially safer and more effective way to treat certain antibiotic-resistant infections.

3 Nov 2025

How Leucine Boosts Cellular Energy Production

Researchers at the University of Cologne have found that a particular dietary amino acid enhances cellular energy, thereby creating new opportunities for the treatment of metabolic disorders.

3 Nov 2025

Genetic Variants Reveal Unexpected Link Between Obesity Risk and Cholesterol Levels

Individuals with a genetic profile that puts them at risk of obesity may not necessarily be at risk of having high cholesterol, UTHealth Houston researchers discovered.

31 Oct 2025

New Method Doubles Therapeutic Cell Production for Duchenne Muscular Dystrophy

If cancer is a disease of overabundance, where cells divide without restraint and tumors grow despite the body's best interests, then degenerative diseases are disorders of deprivation.

31 Oct 2025

How Gut Bacteria Influence Mammalian Cell Physiology

The microbiome-the trillions of bacteria, viruses, and fungi that live quietly in our body-plays a crucial role in shaping human health by providing a variety of micronutrients necessary for vital functions.

30 Oct 2025

RNA Modifications Found to Guide Stem Cell Development into Retinal Cells

Cells contain a blueprint in the form of DNA that dictates what they can make.

29 Oct 2025

AI-Guided Protein Engineering Creates Smart Receptors for Cancer Immunotherapy

Cancer immunotherapy, especially using T cells, is showing a lot of promise in treating blood cancers. Bioengineered T cells, especially those equipped with chimeric antigen receptors (CAR-T cells), have revolutionized cancer treatment.

29 Oct 2025