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Innovative Insights into the Interplay Between Proteins and Small Molecules

With the support of a Maximizing Investigators' Research Award, or MIRA, from the National Institutes of Health, Michigan State University researcher Aleksandra Skirycz is making fundamental discoveries linked to the health and resilience of plants and animals.

4 Nov 2024

ALDH3A2 Enzyme Controls Red-Yellow Pigment Balance in Parrots

A single enzyme fine-tunes red and yellow pigments in parrots' polychromatic plumage, according to a new study. The findings reveal new insights into the molecular mechanisms underlying the evolution and display of color variation in one of nature's most colorful birds. Colors play a central role in ecological adaptation and communication in the natural world.

4 Nov 2024

New Lab-Grown Lip Cells Could Transform Research and Treatment for Disfiguring Lip Conditions

We use our lips to talk, eat, drink, and breathe; they signal our emotions, health, and aesthetic beauty. It takes a complex structure to perform so many roles, so lip problems can be hard to repair effectively. Basic research is essential to improving these treatments, but until now, models using lip cells -; which perform differently to other skin cells -; have not been available.

4 Nov 2024

MicroQuin's Space Research Paves Way for Potential Cancer Treatment

In October, we think pink, and for a good reason—one out of every eight women will be diagnosed with breast cancer in their lifetime, and each year, 2 million women are given this frightening diagnosis.

4 Nov 2024

Immortalized Lip Cells Open Doors for Testing New Therapies

4 Nov 2024

Chloroplast-Infused Cells Revolutionize Tissue Engineering

Recent research from Japan has demonstrated that chloroplasts from algae can be integrated into hamster cells, allowing these cells to perform photosynthesis.

1 Nov 2024

Understanding the Dynamics of Stem Cells

Age influences stem cell survival and immune diversity, according to new research on the long-term dynamics of transplanted stem cells in a patient’s body.

1 Nov 2024

A New Understanding of Viral Infection

Scientists studying animal viruses with the potential to infect humans have discovered a critical protein that could facilitate the spread of a family of organisms known as arteriviruses.

1 Nov 2024

New Discovery Shows TAGLN2 Protein Boosts T Cell Immunity Against Tumors by Enhancing Lipid Metabolism

Findings indicate ovarian cancer disrupts CD8+ T cell metabolism through FABP5 and TAGLN2, suggesting new therapeutic targets for enhancing immune function.

1 Nov 2024

Biologgers Enhance Understanding of Animal Behavior in Nature

Biologgers allow us to see with unprecedented precision how animals move and behave in the wild. But that's only part of the picture, according to a UC Santa Cruz ecologist renowned for using biologging data to tell the deeper story about the lives of marine mammals in a changing world.

1 Nov 2024

Necroptosis Emerges as a Key Target in Alzheimer's Disease

Alzheimer's disease is characterized by a progressive loss of nerve cells leading to a decline in memory and cognition. A team of researchers at KU Leuven and VIB explored the molecular sequence of events in this cellular demise and identified specific inhibitors that could prevent the loss of nerve cells in different mouse models of the disease.

1 Nov 2024

Unraveling the Spatial Complexity of Gene Expression with Seq-Scope

A new method, developed by University of Michigan researchers, creates images that are worth many gigabytes of data, which could revolutionize the way biologists study gene expression. Seq-Scope, developed by Jun Hee Lee, Ph.D., Hyun Min Kang, Ph.D., and their colleagues, was first described in Cell in 2021 as the first method to analyze gene expression at sub micrometer-scale spatial resolution.

1 Nov 2024

A New Method to Reprogram Plant Cells Offers Insights into Cell Wall Development

A new method developed by Penn State biologists allows them to turn stripped-down plant cells into other types of cells, similar to the way stem cells differentiate into different cell types. Using this method, the research team explored the banding patterns that increase the stability of plant cell walls -; much like the corrugated patterns in cardboard -; and how they are created.

1 Nov 2024

New Insights into the Mechanism of Glycan Branch Formation

Glycans are sugar chains that bind to cells via proteins or lipids, altering their chemical properties

30 Oct 2024

Novel Approach to Predict and Optimize CAR-T Cell Therapy

A significant turning point in the battle against cancer has been the recent development of CAR-T technology.

30 Oct 2024

Study Links Archaic Gene Variant to Health Risks in First Nations Oceanians

An ancient gene mutation among First Nations inhabitants of Oceania may make them more susceptible to infectious diseases like influenza, according to a new study by scientists at the University of Colorado Anschutz Medical Campus.

30 Oct 2024

Study Reveals How Cells Rearrange Cytoskeletal Structures During Division

A living cell is a bustling metropolis, with countless molecules and proteins navigating crowded spaces in every direction.

30 Oct 2024

Encrypted Peptides Offer Hope Against Antibiotic-Resistant Infections

Researchers have discovered a new class of antimicrobial compounds called encrypted peptides, which could boost the immune system's toolkit to combat infection and counteract the growing problem of antibiotic-resistant bacteria.

29 Oct 2024

Unveiling the Molecular Mechanisms of CRISPR-Cas10's Cellular Shutdown

CRISPR-Cas9 can elegantly and precisely cut away any desired region of DNA and has long been compared to a type of genetic scissors.

29 Oct 2024

Innovative Genomic Technology Uncovers Mechanisms of Marjolin's Ulcer

Researchers utilized specialized genomic technology at the University of Calgary to enhance our understanding of Marjolin's ulcer (MU), a rare, highly aggressive skin cancer that affects chronic wounds that can often arise from established scars like those caused by severe burns.

29 Oct 2024