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New Metabolic Map Reveals How Blood Stem Cells Age and Become Diseased

Researchers from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg and ETH Zürich have created the first integrated map detailing the metabolic and molecular changes in human blood stem cells as they age, specialize, or turn cancerous.

16 Jul 2025

Pathogenic Bacteria Choose Food Over Fear in the Human Gut

Bacteria that cause intestinal infections typically avoid a stinky chemical - one that can kill them at high enough concentrations - inside human intestines, but they may actually swim toward it when a hearty meal is the reward.

16 Jul 2025

New Computational Tool Enhances Gene Discovery in Heart and Metabolic Diseases

Genetic changes can signal evidence of disease, but pinpointing which genes and what's changed can be difficult.

16 Jul 2025

Candida Auris Uses Distinct Defense Mechanism to Survive Antifungal Treatments

A groundbreaking study from Michigan State University (MSU), recently published in Nature Communications, has revealed how the multidrug-resistant superfungus Candida auris uniquely reconstructs its cell wall to survive antifungal treatments.

16 Jul 2025

New Study Identifies Five Core Principles Preserving Tissue Structure

The human body undergoes a daily replacement of billions of cells, but the tissues remain flawlessly organized. How can that be?

16 Jul 2025

Regulators of Cancer Cell Communication During Invasion

This study identifies key genes regulating neural crest functions in melanoma, revealing insights into collective migration and potential therapeutic targets.

16 Jul 2025

MiROM Uses Infrared Light to Detect Protein Changes in Single Cells

MiROM identifies proteins by using mid-infrared light to detect molecular vibrations – essentially the natural "dance" of molecules within protein structures.

16 Jul 2025

New Research Reveals Key Protein Behind Plant Heat Tolerance

While humans can escape the heat by seeking shade or shedding layers, plants remain rooted in place. So how do they survive extreme heat? It's a question many have wondered-and now, science has an answer.

15 Jul 2025

AI Model Predicts Human Age from Just Two Genomic Regions

Researchers at the Hebrew University have developed an exceptionally accurate method for predicting chronological age from DNA, based on two short genomic regions.

15 Jul 2025

New Research Uncovers Why Some Ecosystems Collapse Suddenly—And Others Don’t

A new study published in the journal One Earth reveals that the way ecosystems collapse—abruptly or gradually—may depend on internal complexity, much like how magnetic materials behave under stress.

15 Jul 2025

Breakthrough Imaging Technique Reveals Mitochondrial Dynamics in Living Tissues

In this study, researcher developed a new imaging approach that combines two powerful techniques to solve this problem. First, a special type of microscope called a two-photon microscope is used, which can look deep into live tissues with minimal damage.

14 Jul 2025

Paternal miRNAs Play Unexpected Role in Seed Viability and Embryogenesis

By using targeted gene silencing in different pollen cell types, the study reveals that disrupting DCL1 function either in the vegetative cell or in sperm cells leads to defective seed formation.

14 Jul 2025

Researchers Uncover Complex Substrate Profile for Enzyme Action

Research on γ-secretase reveals its unique substrate recognition mechanism, offering potential for developing precise therapeutic agents for various diseases.

14 Jul 2025

Rutgers Scientists Uncover Protein Key to Learning and Memory

Scientists have discovered how a key protein helps maintain strong connections between brain cells that are crucial for learning and memory.

14 Jul 2025

New Microchip Maps Antibody Responses Using Just a Drop of Blood

A new microchip invented by Scripps Research scientists can reveal how a person's antibodies interact with viruses-using just a drop of blood.

14 Jul 2025

LINE1 Retrotransposon Found to Exploit Dormant Protein in Human Cells

An international research team led by Freiburg biologists Dr. Wenjing Qi and Prof. Ralf Baumeister has discovered how the LINE1 retrotransposon exploits a cell protein to become active itself, as occurs in tumors.

14 Jul 2025

Microglia Replacement Halts Progression of Fatal Neurological Disease in Mice and Humans

Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a progressive neurological disease with an average age of onset of 43 years and an average life expectancy of only 3 to 5 years after symptoms begin.

11 Jul 2025

Bacteria Show Unexpected Flexibility in Building Their Cell Walls

Closely related bacterial species use different strategies to build their cell walls, an international team of scientists led by Université de Montréal microbiology professor Yves Brun has found.

10 Jul 2025

Exercise Boosts Immune Response in Cancer Through Bacterial Metabolites

A new study from the University of Pittsburgh shows for the first time how exercise improves cancer outcomes and enhances response to immunotherapy in mice by reshaping the gut microbiome.

10 Jul 2025

Ancient DNA Reveals Origins of Human Pathogens and Zoonotic Diseases

A research team led by Eske Willerslev, professor at the University of Copenhagen and the University of Cambridge, has recovered ancient DNA from 214 known human pathogens in prehistoric humans from Eurasia.

10 Jul 2025