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SARS-Cov-2 spike proteins can directly impact the function of blood-brain barrier

Like a key, SARS-CoV-2 - the virus that causes coronavirus disease 2019 (COVID-19) - attaches to specific molecules on the host cell surface, opening gateways into the cell interior.

30 Oct 2020

Individuals infected with mild-to-moderate COVID 19 mount a robust antibody response

The vast majority of individuals infected with mild-to-moderate COVID 19 mount a robust antibody response that is relatively stable for at least five months, according to research conducted at the Icahn School of Medicine at Mount Sinai and published October 28, in the journal Science.

29 Oct 2020

Scientists develop controllable system for mimicking biochemical reaction cascades in cells

Researchers at the University of Basel have developed a precisely controllable system for mimicking biochemical reaction cascades in cells. Using microfluidic technology, they produce miniature polymeric reaction containers equipped with the desired properties.

29 Oct 2020

Genetic predispositions affect the efficacy of COVID-19 drugs

A paper recently uploaded to bioRxiv* aimed to utilize genome-wide CRISPR screening to identify genes involved in modulating the activity of COVID-19 drugs.

29 Oct 2020

Study shows potential avenues of COVID-19 vulnerability in patients with diabetic kidney disease

People with diabetes -- especially the 20 to 40 percent with diabetic kidney disease -- are among the most at risk for serious complications and death from COVID-19.

27 Oct 2020

Scientists explain the role of transcription factors in genetic diseases

Transcription factor proteins can be described as the light switches of the human genome. These proteins bind to DNA and allow genes to turn “on” or “off.”

26 Oct 2020

Novel technique could propel personalized treatments for cancer

When it comes to defeating cancer, some immune cells are mightier than others. But even the best-trained eye and today's advanced scientific tools have trouble discerning the most powerful tumor-fighting cells from the rest.

23 Oct 2020

New method for producing FTVI enzyme could enhance therapeutic potential of cord blood transplants

A new way of producing an enzyme called fucosyltransferase VI (FTVI) in the lab could help enhance the therapeutic potential of cord blood transplants.

23 Oct 2020

New research sheds light on the working principles of advanced biosensing technologies

The COVID-19 pandemic is undoubtedly the most challenging global health burden since the 2nd World War. The pandemic has raised social awareness on the importance of effective and timely diagnosis that may help minimize the risk of contracting and spreading COVID-19.

22 Oct 2020

Scientists use molecular dynamics simulations to reveal the secrets of SARS-CoV-2 virus

The virus wreaking havoc on our lives is an efficient infection machine. Comprised of only 29 proteins (compared to our 400,000), with a genome 1/200,000 the size of ours, SARS-CoV-2 is expertly evolved to trick our cells to contribute its machinery to assist in its propagation.

22 Oct 2020

Ancient embedded elements in human DNA can activate powerful immune response to kill cancer cells

Ancient embedded elements in our DNA from generations past can activate a powerful immune response to kill cancer cells like an infection.

22 Oct 2020

Researchers uncover a new cellular mechanism for disposing of misfolded proteins

About 30 years ago, Dr. Richard Sifers set out on a journey to discover why people with a rare condition known as alpha1-antitrypsin (AAT) deficiency present with high variation in the severity of liver disease.

21 Oct 2020

New DNA-cutting tool could advance gene editing for novel treatments

Gene editing for the development of new treatments, and for studying disease as well as normal function in humans and other organisms, may advance more quickly with a new tool for cutting larger pieces of DNA out of a cell's genome, according to a new study by UC San Francisco scientists.

21 Oct 2020

Computational study of the structure and dynamics of glycosylated SARS-CoV-2

SARS-CoV-2 has been shown to enter cells by interaction with ACE2, which is found on the surface of cells in the lungs and throughout the body.

21 Oct 2020

New strategy for capturing interactions among glycans and protein activators in live cells

Human cells are encased by a membrane coated with diverse sugar molecules known as glycans. These glycans play many roles in health and disease, making them important to understand.

20 Oct 2020

Scientists develop novel lab testing procedure for detection of SARS-CoV-2 antibodies

Knowing you have developed antibodies against the SARS-CoV-2 virus after recovering from COVID-19 doesn't tell you everything about your immunity.

20 Oct 2020

A new look at an old technique for studying protein dynamics

A fresh new look at an old technique in protein biochemistry has shown that it should be reintroduced to the spectroscopy toolkit.

20 Oct 2020

Researchers develop new approach that uses DNA-synthesizing biological enzyme

According to current estimates, the amount of data produced by humans and machines is rising at an exponential rate, with the digital universe doubling in size every two years.

19 Oct 2020

Army researchers test alternative ways to measure COVID-19 antibody levels

Researchers with the U.S. Army Futures Command are part of a team that tested alternative ways to measure COVID-19 antibody levels, resulting in a process that is faster, easier and less expensive to use on a large scale. Their method holds promise for accurately identifying potential donors who have the best chance of helping infected patients through convalescent plasma therapy.

15 Oct 2020

Statins can reduce risk of heart attacks and other cardiovascular diseases

According to a study recently published in the eLife journal, cholesterol-lowering drugs, known as statins, may lower cancer risk in humans via a pathway unassociated with cholesterol.

15 Oct 2020

Enzyme News and Research

SARS-Cov-2 spike proteins can directly impact the function of blood-brain barrier

Individuals infected with mild-to-moderate COVID 19 mount a robust antibody response

Scientists develop controllable system for mimicking biochemical reaction cascades in cells

Genetic predispositions affect the efficacy of COVID-19 drugs

Study shows potential avenues of COVID-19 vulnerability in patients with diabetic kidney disease

Scientists explain the role of transcription factors in genetic diseases

Novel technique could propel personalized treatments for cancer

New method for producing FTVI enzyme could enhance therapeutic potential of cord blood transplants

New research sheds light on the working principles of advanced biosensing technologies

Scientists use molecular dynamics simulations to reveal the secrets of SARS-CoV-2 virus

Ancient embedded elements in human DNA can activate powerful immune response to kill cancer cells

Researchers uncover a new cellular mechanism for disposing of misfolded proteins

New DNA-cutting tool could advance gene editing for novel treatments

Computational study of the structure and dynamics of glycosylated SARS-CoV-2

New strategy for capturing interactions among glycans and protein activators in live cells

Scientists develop novel lab testing procedure for detection of SARS-CoV-2 antibodies

A new look at an old technique for studying protein dynamics

Researchers develop new approach that uses DNA-synthesizing biological enzyme

Army researchers test alternative ways to measure COVID-19 antibody levels

Statins can reduce risk of heart attacks and other cardiovascular diseases

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