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The Evolutionary Secrets of Human Hearts

A team from the Max Delbrück Center's Hübner and Diecke Labs demonstrated the genetic differences between human and non-human primate hearts.

25 Sep 2024

The Lasting Effects of COVID-19 on the Brain

In the UK’s largest study to date, novel steps have been taken to gain a better understanding of the immediate and long-term effects of COVID-19 on the brain.

25 Sep 2024

Neutron Scattering Reveals Enzyme Secrets

Scientists have uncovered amazing information about the role of an enzyme that could assist in the development of drugs for aggressive cancers in just two neutron experiments.

25 Sep 2024

New Method Detects Peroxymonocarbonate and Its Role in Cellular Responses

High levels of carbon dioxide (CO2) in the atmosphere can alter not only the climate of our planet but also the functioning of our cells.

24 Sep 2024

Study Uncovers Cholesterol's Role in Membrane Structure and Function

A new study by Rice University researchers led by Jason Hafner could open new pathways for understanding how cholesterol influences cell membranes and their receptors, paving the way for future research on diseases linked to membrane organization.

24 Sep 2024

A Novel Function for STING in DNA Damage Response

A study published in the journal Molecular Cell has shed light on the multifaceted role of STING, a protein previously implicated in antiviral signaling pathways. The study reveals that STING also plays a crucial part in facilitating cellular stress resolution and promoting cell survival.

23 Sep 2024

Unveiling the Molecular Mechanisms of Shigella flexneri Infection

Virginia Tech researchers have learned how bacteria manipulate molecules to infect the host organism.

23 Sep 2024

A New Method to Correct Misplaced Proteins in Cells

Cells are highly controlled spaces that rely on every protein being in the right place. Many diseases, including cancers and neurodegenerative disorders, are associated with misplaced proteins. In some cancers, for instance, a protein that normally stands watch over DNA replicating in the nucleus is sent far from the DNA it is meant to monitor, allowing cancers to grow.

23 Sep 2024

AI-Driven Insights into Lasso Peptide Biosynthesis

Lasso peptides are natural products made by bacteria. Their unusual lasso shape endows them with remarkable stability, protecting them from extreme conditions. In a new study, published in Nature Chemical Biology, researchers have constructed and tested models for how these peptides are made and demonstrated how this information might be used to advance lasso peptide-based drugs into the clinic.

23 Sep 2024

A New Understanding of the Effects of Fever on Immune Cells

Fever temperatures rev up immune cell metabolism, proliferation and activity, but they also -; in a particular subset of T cells -; cause mitochondrial stress, DNA damage and cell death, Vanderbilt University Medical Center researchers have discovered.

23 Sep 2024

Scientists Develop Lab-Grown Muscle Stem Cells for Advanced Regenerative Therapies

Recent findings reveal that induced satellite cells can effectively regenerate muscle tissue, outperforming traditional myoblasts in engraftment and function.

23 Sep 2024

Novel Tool Helps Identify Snake Venom Genes Across Species

Only about ten percent of the world's roughly 4,000 snake species have venom strong enough to seriously hurt a human, but that's enough for snake bites to be an important public health concern.

20 Sep 2024

Sodium Transport Found to Play a Surprising Role in Mitochondrial Energy Production

The GENOXPHOS (Functional Genetics of the Oxidative Phosphorylation System) group at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has discovered a crucial role of sodium in the generation of cellular energy.

20 Sep 2024

Study Finds How Plants Limit Viral Spread to Progeny with RNA Interference

Scientists have learned how plants keep viruses from being passed to their offspring, a finding that could ensure healthier crops.

20 Sep 2024

The Role of Ancient Viral Sequences in Gene Regulation

For any organism to survive and thrive, its cells must tightly control which genes are activated when, and where.

19 Sep 2024

Research Shows a Causal Role of Histone Modifications in Gene Regulation

For any organism to survive and thrive, its cells must strictly control which genes are active when and where.

19 Sep 2024

Epigenetic Switch Found to Activate Genes in Embryos

Researchers led by the Institute of Molecular Biology have found that 5-formylcytosine (5fC), a DNA alteration, acts as an activating epigenetic switch to activate genes during the early stages of embryonic development.

19 Sep 2024

Low Extracellular Sodium Concentrations Can Suppress mRNA Expression in Brain Cells

Brain and mental problems can result from chronic hyponatremia, a disorder marked by low blood salt levels.

19 Sep 2024

COI1 Proteins in Maize Show Unexpected Functions for Crop Improvement

Maize (corn) is one of the most important staple crops in the world and has been extensively studied. Yet, many aspects of the genetic mechanisms regulating its growth and development remain unexplored.

19 Sep 2024

IgM Antibodies Offer Protection Against Staph Infections

One of the main sources of community- and hospital-acquired infections is Staphylococcus aureus, well known for its antibiotic-resistant variation Methicillin-resistant Staphylococcus aureus (MRSA)

18 Sep 2024