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New test to detect substances that are harmful to the placenta and embryo

Researchers at ETH Zurich have developed a cell culture test to detect substances that are directly or indirectly harmful to embryos. Based on an existing test used for developing new drugs and chemicals, the augmented version is designed to help reduce the number of animal experiments.

22 Jul 2021

Study identifies many small molecules that bind to certain areas of the SARS-CoV-2 genome

Scientists at Goethe University have now identified some regions of the SARS-CoV-2 genome that might be an ideal target for future drugs.

21 Jul 2021

Research substantiates nanoparticles as promising platforms for cell nano-sensors

Researchers published an article that represents the transmission electron microscopy (TEM) and flow cytometry study of A-549 (human lung carcinoma) cellular uptake of Pr3+:LaF3 nanoparticles.

21 Jul 2021

Study unravels the biomechanical, biophysical response of cancer cells to drugs

A new study reports the use of single-cell, force spectroscopy methods to probe biophysical and biomechanical kinetics of cancer cells.

21 Jul 2021

Study holds phages responsible for superbug emergence

Scientists unraveled that phages are responsible for the initiation of rapid bacterial evolution that leads to the rise of treatment-resistant “superbugs.”

From University of Pittsburgh 21 Jul 2021

Atomic force spectroscopy probes cellular biomechanics in response to drugs in hypoxia

Oncotarget published "Dynamic cellular biomechanics in responses to chemotherapeutic drug in hypoxia probed by atomic force spectroscopy" which reported that by exploiting single-cell, force spectroscopy methods, the authors probed biophysical and biomechanical kinetics of brain, breast, prostate, and pancreatic cancer cells with standard chemotherapeutic drugs in normoxia and hypoxia over 12-24 hours.

20 Jul 2021

Researchers use body-on-a-chip cancer models to study personalized immunotherapy response

Wake Forest researchers and clinicians are using patient-specific tumor 'organoid' models as a preclinical companion platform to better evaluate immunotherapy treatment for appendiceal cancer, one of the rarest cancers affecting only 1 in 100,000 people.

20 Jul 2021

New study identifies two genetic regions linked to cluster headache

Scientists have performed the largest-ever study seeking genetic markers for cluster headache.

16 Jul 2021

$Microcrystal electron diffraction could help obtain potential pharmaceutical structures$

Microcrystal electron diffraction could help obtain potential pharmaceutical structures

In the process of drug development, solving structures of potential therapeutics with X-ray diffraction (XRD) has been a presumed, critical step so far.

16 Jul 2021

AMSBIO launches new range of biosimilar antibodies for research use

AMSBIO has launched a new range of research grade biosimilars that enable analysis of biological processes without the need to purchase expensive therapeutic-grade biologics.

From AMS Biotechnology 15 Jul 2021

Researchers develop novel technique to control tiny water droplets in lab-on-a-chip applications

Scientists develop a method to better manipulate tiny droplets in lab-on-a-chip applications for biochemistry, cell culturing, and drug screening.

12 Jul 2021

New screening method allows identification of drugs that glue proteins together

Scientists developed a new screening method that tests the effectiveness of therapeutic molecules developed to “glue” proteins together in the body.

9 Jul 2021

Emerging variants of COVID-19 could be treated with a new anticoagulant drug

The capacity of the COVID-19 virus’s spikes to bind to human cells may be hampered by molecules from the same family as the anticoagulant medication heparin.

9 Jul 2021

Study reveals how fine-tuning the immune system can improve vaccines, reduce disease severity

Immunologists have discovered a molecular route that regulates how crucial immune cells evolve into the immune system’s functioning components.

9 Jul 2021

Universal stem cells exhibit the potential for more cost-effective cell therapy

Researchers have demonstrated that gene-edited cellular treatments can effectively treat cardiovascular and pulmonary disorders.

8 Jul 2021

Lipidomics study reveals schizophrenic patients’ resistance to antipsychotic drugs

Scientists discovered 22 lipids in the blood plasma of schizophrenia patients that were linked to slower symptom improvement over time.

8 Jul 2021

Combating drug-resistant pathogens using genetically modified immune cells

As part of the drive to support junior research groups in research into infectious diseases, the Federal Ministry of Education and Research is to provide 2,162,188 euros in funding from 2021 to 2026 for the research project 'AGEnTS - Genetic Engineering of T-cells for Treating Infectious Diseases' at Friedrich-Alexander University Erlangen-Nürnberg (FAU).

7 Jul 2021

New method yields 10 times more accessible details of gene activity in individual cells

Researchers have devised a way to multiply by more than ten-fold the accessible details of gene activity in individual cells. It's a big leap in the effort to understand cancer development, brain function, immunity and other biological processes driven by the complex interactions of multitudes of different cell types.

7 Jul 2021

Scientists are paving the way for cancer treatments with fewer side effects

In recent years, immunotherapy has revolutionized the field of cancer treatment. However, inflammatory reactions in healthy tissues frequently trigger side effects that can be serious and lead to the permanent discontinuation of treatment.

5 Jul 2021

Experimental model reveals the protective role of antioxidants in neurodegenerative disorders

Researchers used a model to replicate the blood-brain barrier and successfully demonstrated how antibody guards the brain against inflammation.

2 Jul 2021

Drugs News and Research

New test to detect substances that are harmful to the placenta and embryo

Study identifies many small molecules that bind to certain areas of the SARS-CoV-2 genome

Research substantiates nanoparticles as promising platforms for cell nano-sensors

Study unravels the biomechanical, biophysical response of cancer cells to drugs

Study holds phages responsible for superbug emergence

Atomic force spectroscopy probes cellular biomechanics in response to drugs in hypoxia

Researchers use body-on-a-chip cancer models to study personalized immunotherapy response

New study identifies two genetic regions linked to cluster headache

Microcrystal electron diffraction could help obtain potential pharmaceutical structures

AMSBIO launches new range of biosimilar antibodies for research use

Researchers develop novel technique to control tiny water droplets in lab-on-a-chip applications

New screening method allows identification of drugs that glue proteins together

Emerging variants of COVID-19 could be treated with a new anticoagulant drug

Study reveals how fine-tuning the immune system can improve vaccines, reduce disease severity

Universal stem cells exhibit the potential for more cost-effective cell therapy

Lipidomics study reveals schizophrenic patients’ resistance to antipsychotic drugs

Combating drug-resistant pathogens using genetically modified immune cells

New method yields 10 times more accessible details of gene activity in individual cells

Scientists are paving the way for cancer treatments with fewer side effects

Experimental model reveals the protective role of antioxidants in neurodegenerative disorders

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