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Study Reveals 70 Million Years of Host-Parasite Genetic Arms Race

Hosts and their parasites are in constant competition. Through genetic diversity, the host can change in such a way that infection is no longer possible.

8 Aug 2024

High-Resolution Spatial Transcriptomics at Lower Cost

A novel spatial transcriptomics method that could revolutionize tissue sample gene expression profiling.

7 Aug 2024

Mini-Gut Model Unlocks Secrets of COVID-19 Diarrhea

Researchers at Johns Hopkins Medicine claim to have identified multiple molecular pathways linked to diarrhea caused by COVID-19, offering possible therapeutic interventions utilizing human stem cells to create a sort of “mini intestine-in-a-dish.

7 Aug 2024

Study Explores the Role of Sex-Biased Gene Expression in Autism Risk During Prenatal Development

The cortex of prenatal donors to determine differentially expressed genes based on sex and potentially identify molecular and cellular mechanisms that contribute to ASD.

7 Aug 2024

Genetic Analysis of Potato and Phytophthora infestans During and After the Irish Potato Famine

In an examination of the genetic material found in historic potato leaves, North Carolina State University researchers reveal more about the tit-for-tat evolutionary changes occurring in both potato plants and the pathogen that caused the 1840s Irish potato famine.

6 Aug 2024

Lipid Nanoparticle-Encapsulated miR-193a-3p Mimic INT-1B3 Boosts Anti-Tumor Immunity

A new research paper was published in Oncotarget's Volume 15 on July 12, 2024, entitled, "INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death."

6 Aug 2024

Cyclo(L-Pro-L-Tyr): A Promising Tyrosinase Inhibitor Derived from Skin Bacteria

Melanin protects the skin-;the body's largest organ and a vital component of the immune system-;from the damaging effects of ultraviolet (UV) radiation.

6 Aug 2024

Unveiling the Roots of Deadly Infant Leukemia

Researchers at the Josep Carreras Leukaemia Research Institute have identified the genetic foundation for newborn B-cell Acute Lymphoblastic Leukaemia (B-ALL) glucocorticoid resistance through MLL gene rearrangements.

6 Aug 2024

Discovery of Novel Macrophage Population Offers Hope for Lung Repair Post-Viral Infection

Researchers at the University of Liège (Belgium) have discovered a new population of macrophages, important innate immune cells that populate the lungs after injury caused by respiratory viruses.

5 Aug 2024

Mast Cells Recruit Neutrophils in Immune Response

Mast cells are well-known for their part in allergic reactions, but the immune system relies heavily on them. They release chemicals in response to allergens, which cause common allergy symptoms like tissue swelling and inflammation.

5 Aug 2024

Shared Mechanisms in Human and Yeast DNA Replication Revealed

Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies published in the journals Science and Proceedings of the National Academy of Sciences.

5 Aug 2024

Megamonas Bacteria Identified as Potential Obesity Culprit

A recent study from Cell Host & Microbe identifies Megamonas as a possible bacteria linked to obesity based on a large-scale cohort of obese Chinese people. This study demonstrates how the bacterium increases lipid absorption, breaks down intestinal myo-inositol, and causes obesity, which may lead to future approaches for managing obesity.

5 Aug 2024

Researchers Uncover How Phage Infection Dynamics Affect Viral Entry at Single-Cell Level

The process by which phages-;viruses that infect and replicate within bacteria-;enter cells has been studied for over 50 years.

5 Aug 2024

Breakthrough Method Captures Aging Impact on Alzheimer’s Disease in Lab-Grown Neurons

Researchers at Washington University School of Medicine in St. Louis have developed a way to capture the effects of aging in the development of Alzheimer's disease.

2 Aug 2024

Geographic Origin Plays Key Role in Tuberculosis Infection, Harvard Study Finds

For some forms of tuberculosis, the chances that an exposed person will get infected depend on whether the individual and the bacteria share a hometown, according to a new study comparing how different strains move through mixed populations in cosmopolitan cities.

2 Aug 2024

Innovative Nanosensing Method Promises Safer Gene Therapy with Improved AAV Vector Quality

Over the past few decades, there has been remarkable progress in genetic manipulation technologies, bringing us closer to the point where genes can be modified in vivo.

2 Aug 2024

Novel Microscopy Method Revolutionizes Imaging with Reduced Radiation and Faster Results

An international team of scientists, led by Trinity College Dublin, has devised an innovative imaging method using state-of-the-art microscopes that significantly reduces the time and radiation required.

1 Aug 2024

Highly Reactive RNA Building Blocks for Enhanced Chip Production

A multinational research team under the direction of the University of Vienna has been successful in creating new RNA building blocks that exhibit increased photosensitivity and chemical reactivity. In biotechnological and medical research, RNA chips can be produced much faster as a result of this.

1 Aug 2024

Revealing the Spatial Dynamics of Sebum Production

Changes in gene expression in sebaceous glands have been spatially mapped for the first time in a collaborative project between Leipzig University's Interdisciplinary Centre for Bioinformatics (IZBI) and the Faculty of Veterinary Medicine.

1 Aug 2024

Discovery of Immune Cell Reservoirs Near Glioblastomas Offers New Treatment Possibilities

Glioblastomas are highly aggressive, usually incurable brain tumors. If all therapeutic options are exhausted, patients have an average life expectancy of less than two years.

1 Aug 2024

Research News and Research

Study Reveals 70 Million Years of Host-Parasite Genetic Arms Race

High-Resolution Spatial Transcriptomics at Lower Cost

Mini-Gut Model Unlocks Secrets of COVID-19 Diarrhea

Study Explores the Role of Sex-Biased Gene Expression in Autism Risk During Prenatal Development

Genetic Analysis of Potato and Phytophthora infestans During and After the Irish Potato Famine

Lipid Nanoparticle-Encapsulated miR-193a-3p Mimic INT-1B3 Boosts Anti-Tumor Immunity

Cyclo(L-Pro-L-Tyr): A Promising Tyrosinase Inhibitor Derived from Skin Bacteria

Unveiling the Roots of Deadly Infant Leukemia

Discovery of Novel Macrophage Population Offers Hope for Lung Repair Post-Viral Infection

Mast Cells Recruit Neutrophils in Immune Response

Shared Mechanisms in Human and Yeast DNA Replication Revealed

Megamonas Bacteria Identified as Potential Obesity Culprit

Researchers Uncover How Phage Infection Dynamics Affect Viral Entry at Single-Cell Level

Breakthrough Method Captures Aging Impact on Alzheimer’s Disease in Lab-Grown Neurons

Geographic Origin Plays Key Role in Tuberculosis Infection, Harvard Study Finds

Innovative Nanosensing Method Promises Safer Gene Therapy with Improved AAV Vector Quality

Novel Microscopy Method Revolutionizes Imaging with Reduced Radiation and Faster Results

Highly Reactive RNA Building Blocks for Enhanced Chip Production

Revealing the Spatial Dynamics of Sebum Production

Discovery of Immune Cell Reservoirs Near Glioblastomas Offers New Treatment Possibilities

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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