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Microbiome manipulation to prevent and cure diseases

Tagbo Niepa, assistant professor of chemical engineering at the University of Pittsburgh, is inspired by this possibility in his research. His work on using the microbiome to enhance human health was recognized with a $2 million New Innovator Award from the National Institutes of Health, which funds “exceptionally creative scientists proposing high-risk, high-impact research.”

From University of Pittsburgh 5 Oct 2022

Research team outlines three-step technique that lets human body defend against Hep B

A team from the University of Geneva (UNIGE) has unraveled the precise operation of this defensive mechanism after finding a crucial protein complex that is active when our body is infected by the virus, paving the path for novel treatment targets.

5 Oct 2022

The strategy used by metastatic cancer cells to invade the liver identified

The alternative pathway for liver metastasis has been revealed by a team of researchers.

5 Oct 2022

Research shows readily available pharmaceutical manufacturing capacity in the United States

President Joe Biden signed an executive order Sept. 12 to launch a National Biotechnology and Biomanufacturing Initiative, noting the United States relies too heavily on foreign materials and foreign bioproduction.

5 Oct 2022

Newly isolated Bacteroides likely to be present in mammals beyond mice

In the DFG-funded Collaborative Research Center (CRC) 1182 “Origin and Function of Metaorganisms,” scientists from Kiel University and the Max Planck Institute for Evolutionary Biology in Plön (MPI-EB) are investigating the evolutionary history and function of Bacteroides.

From The Max Planck Institute 30 Sep 2022

New guidelines to generate high-quality, well-structured organoids

Researchers have opened a new avenue for investigations of neurological development, disease, and therapies that cannot be undertaken in living people by employing stem cells to grow small brain-like structures in the lab.

30 Sep 2022

Transforming “tissue engineering” into a reality

The National Institute of Biomedical Imaging and Bioengineering awarded Case Western Reserve $6.1 million to develop body tissue engineering.

29 Sep 2022

“Junk” DNA could provide access to innovative treatments for neurological conditions

The breakthrough study from the University of Sheffield’s Neuroscience Institute and Healthy Lifespan Institute offers critical new insights into the so-called junk DNA, or DNA that was previously believed to be unimportant to the coding of the genome, and how it affects neurological disorders like Motor Neuron Disease (MND) and Alzheimer’s.

29 Sep 2022

Highly effective and safe Zika vaccine technology

Scientists from the University of California, Los Angeles (UCLA) have discovered a Zika vaccine technology that is very safe and effective in preclinical mouse models.

29 Sep 2022

New insights into the regulatory mechanisms of cell fate decisions

The Babraham Institute’s Reik lab’s study has improved the understanding of the function of DNA methylation during the early stages of development.

29 Sep 2022

Cryo-EM solves the decades-old mystery of bacterial movement

Scientists from the University of Virginia School of Medicine and their colleagues have discovered a decades-old mystery regarding how E. coli and other bacteria move.

28 Sep 2022

The exchange of nutrients between the mother and fetus mirrored by ‘placenta-on-a-chip’

Plasmodium falciparum infections can result in placental malaria, which can have serious consequences for both mother and child. Nearly 200,000 newborn fatalities annually from placental malaria, primarily as a result of low birth weight, as well as 10,000 maternal deaths.

27 Sep 2022

WEHI receives $2.5 million fund to develop personalized cancer treatments

With a $2.5 million fund received from the Medical Research Future Fund (MRFF), a new genomics project led by WEHI will develop precision medicine and customized cancer therapy for Australians.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 27 Sep 2022

Carp virus provides significant insights into immunology

In an article published in the journal Nucleic Acids Research, the team led by Prof. Alain Vanderplasschen, a virologist and immunologist at the University of Liège, describes 10 years of research on how a carp virus uses a protein domain called Zalpha (Zα) to inhibit the host cell’s defense mechanisms.

26 Sep 2022

Rutgers researchers seek to develop technology for protein editing

Rutgers researchers are seeking to develop the technology to modify or "edit" protein molecules in the body-;an advance that could spur major breakthroughs in human health.

From Rutgers University 26 Sep 2022

The biological advantages of sperm swimming in groups

Sperm actually swim better together when they are swimming against the current. Contrary to common belief, spermatozoa frequently cooperate to go through the female reproductive system in a variety of mammalian species, contradicting the notion that the fastest and fittest male reproductive cell wins the fertilization race.

22 Sep 2022