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Loss of Matrix Receptors Impairs Actin Cytoskeleton Remodeling, Cell Spreading, and Osteogenic Differentiation

During bone healing, skeletal progenitor cells (SPCs), which can multiply and develop into bone-forming cells, move to the injury site and help build new bone.

9 Sep 2026

Novel T-Cell Engineering Strategy Prevents Deadly Osteosarcoma Lung Metastasis

Scientists at St. Jude Children's Research Hospital have discovered that removing the gene for Regnase-1 from engineered immune cells makes them more effective at treating relapsed osteosarcoma.

26 Aug 2026

Neural Stem Cell Protein CCN1 Guides Microglial Distribution During Development

The development of the central nervous system (CNS) depends on the coordinated interactions between neural stem cells (NSCs) and resident immune cells to regulate neurogenesis, tissue organization, and brain maturation.

12 Aug 2026

Method Reveals How Influenza A Takes Over Host Cell Machinery

A new study identifies influenza A virus interactions with human proteins, uncovering mechanisms of paraspeckle disruption and insights for antiviral development.

4 Aug 2026

Study Provides New Insights for the Development of Novel Antifungal Drug Targets

This study was conducted by the research group of Professor Liao Guojian from the College of Pharmaceutical Sciences, Southwest University. Candidate genes potentially involved in lysine synthesis in C. neoformans were identified and knocked out.

29 Jul 2026

CRISPR Technology Enables First Successful Gene Editing in Biting Midges

Scientists have successfully edited the genome of biting midges, opening the door to new research on how these insects transmit disease.

20 Jul 2026

Nature Study Reveals Hidden Genes Driving Hard-to-Treat Tumors

Researchers have solved a long-standing mystery of how abnormal chromosomes drive cancer, identifying 81 new genes involved in aggressive breast cancer.

9 Jul 2026

Microtubule-Stabilizing Protein Camsap3 Proves Essential for Female Fertility

Female fertility depends on the successful growth and maturation of eggs (oocytes) within ovarian follicles.

3 Jul 2026

Single Nucleus RNA Sequencing Decodes Tomato Plant Early Stage Development

Seedling emergence is one of the most vulnerable stages in plant life. In darkness, seedlings undergo skotomorphogenesis, forming elongated hypocotyls and curved apical hooks that protect the shoot tip as it pushes through soil.

29 Jun 2026

Researchers Compare Embryonic and Adult Mouse Brain Targets to Map Memory Networks

A peer-reviewed invited review published today in Genomic Psychiatry argues that the adult brain, when it learns and remembers and rewires, is not inventing something new.

20 May 2026

Discovery of Heme Transport Pathway Solves Longstanding Red Blood Cell Enigma

Scientists have long been puzzled by how maturing red blood cells manage to produce all the hemoglobin they need to carry oxygen to tissues, even after shedding the vital structures they need to produce it.

25 Apr 2026

How Mitochondrial Damage Accelerates Stem Cell Aging

Hematopoietic stem cells (HSCs), the cells that produce all blood cell types, start to lose their efficacy as one ages, which eventually reduces the ability to maintain healthy blood and a robust immune system.

17 Apr 2026

Kinesin Motor Protein Variations Control Cargo Specificity in Neuronal Transport

Intracellular transport is a vital process that allows cells to move proteins and other molecules to specific locations.

13 Apr 2026

Chemical Strategy Unlocks Pollutant Degradation Potential in Native Soil Bacteria

Aromatic compounds, such as dioxins and benzene, are major soil pollutants. Their high chemical stability makes them resistant to microbial and chemical degradation, leading to toxic accumulation in the soil.

10 Apr 2026

Mice Study Reveals Cholecystokinin as Key Driver of Obesity-Related Pancreatic Cancer

Obesity increases the body's need for insulin, forcing cells in the pancreas known as beta cells to ramp up insulin production to maintain blood sugar levels.

22 Mar 2026

Three CBX2 Molecules Found to Orchestrate Essential Stem Cell Fate Decisions

A new study has uncovered how an exceptionally scarce protein can orchestrate the assembly of large‑scale gene-silencing structures inside cells, and what happens when that process breaks down.

6 Mar 2026

Extracellular Matrix Sensing Enables Pancreatic Cancer Cells to Regulate Autophagy Levels

A feature of pancreatic cancer cells' surroundings determines whether they grow fast or become resistant to chemotherapy, a new study shows.

17 Feb 2026

Bone-building hormone eases chronic low back pain by restoring vertebral microarchitecture

Parathyroid hormone shows promise in treating low back pain by remodeling degenerating vertebral endplates and limiting pathological sensory innervation.

12 Feb 2026

Parallel Molecular Routes Ensure Accurate Centromere Specification During Cell Division

Despite the immense amount of genetic material present in each cell, around three billion base pairs in humans, this material needs to be accurately divided in two and allocated in equal quantities.

9 Jan 2026

Genetic Factor "Fru" Influences Bees' Cooperative Food-Seeking Behavior

A team of biologists from Heinrich Heine University Düsseldorf (HHU), along with researchers from Bochum and Paris, has uncovered a genetic component underlying intricate social behaviors in bees.

24 Dec 2025

Knockout News and Research

Loss of Matrix Receptors Impairs Actin Cytoskeleton Remodeling, Cell Spreading, and Osteogenic Differentiation

Novel T-Cell Engineering Strategy Prevents Deadly Osteosarcoma Lung Metastasis

Neural Stem Cell Protein CCN1 Guides Microglial Distribution During Development

Method Reveals How Influenza A Takes Over Host Cell Machinery

Study Provides New Insights for the Development of Novel Antifungal Drug Targets

CRISPR Technology Enables First Successful Gene Editing in Biting Midges

Nature Study Reveals Hidden Genes Driving Hard-to-Treat Tumors

Microtubule-Stabilizing Protein Camsap3 Proves Essential for Female Fertility

Single Nucleus RNA Sequencing Decodes Tomato Plant Early Stage Development

Researchers Compare Embryonic and Adult Mouse Brain Targets to Map Memory Networks

Discovery of Heme Transport Pathway Solves Longstanding Red Blood Cell Enigma

How Mitochondrial Damage Accelerates Stem Cell Aging

Kinesin Motor Protein Variations Control Cargo Specificity in Neuronal Transport

Chemical Strategy Unlocks Pollutant Degradation Potential in Native Soil Bacteria

Mice Study Reveals Cholecystokinin as Key Driver of Obesity-Related Pancreatic Cancer

Three CBX2 Molecules Found to Orchestrate Essential Stem Cell Fate Decisions

Extracellular Matrix Sensing Enables Pancreatic Cancer Cells to Regulate Autophagy Levels

Bone-building hormone eases chronic low back pain by restoring vertebral microarchitecture

Parallel Molecular Routes Ensure Accurate Centromere Specification During Cell Division

Genetic Factor "Fru" Influences Bees' Cooperative Food-Seeking Behavior

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