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Microbial Molecule Controls Cancer Progression and Boosts Chemotherapy

An international team of scientists led by researchers from the MRC Laboratory of Medical Sciences (LMS), Imperial College London, and the University of Cologne discovered that microbes associated with tumors produce a molecule that can control cancer progression and improve chemotherapy efficacy.

15 Sep 2025

Adaptive Microfluidic Channel Enhances Impedance Flow Cytometry Sensitivity

Many advances in medicine and drug development were possible owing to flow cytometry, a single-cell analysis technique that analyzes cells using the emitted fluorescence of their chemical tags while passing through a laser beam.

13 Sep 2025

Metastatic Lung Cancer Cells Cozy Up to Neurons and Form Synapses

Small cell lung cancer cells that metastasize to the brain cozy up to neurons and form working electrical connections, called synapses, according to an upcoming study led by Stanford Medicine researchers.

11 Sep 2025

Researchers Discover Giant DNA Elements Hidden in the Human Mouth

Researchers including those at the University of Tokyo have made a surprising discovery hiding in people's mouths: Inocles, giant DNA elements that had previously escaped detection.

10 Sep 2025

Predicting Protein Metal Binding with New Artificial Intelligence Model

Biologists and computational scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory recently refined two artificial intelligence (AI) programs originally built by Meta, the company that owns Facebook, to predict protein shapes.

10 Sep 2025

Researchers Develop New Technique to Detect Causality in Neural Spike Trains

Understanding the brain's functional architecture is a fundamental challenge in neuroscience. The connections between neurons ultimately dictate how information is processed, transmitted, stored, and retrieved, thus forming the basis of our cognitive functions.

10 Sep 2025

New Research Highlights a More Efficient CAR T Treatment

This review article focuses on the transformative potential of in vivo CAR T cell treatment in overcoming the constraints of standard CAR T cell production.

8 Sep 2025

Intestinal Cells Pull Rather Than Push to Remove Weaker Neighbors

Cells on the inner surface of the intestine are replaced every few days. But, how does this work? It was always assumed that cells leave the intestinal surface because excess cells are pushed out. In a recent publication in the journal Science, researchers of the Hubrecht Institute and AMOLF show that this is not correct.

4 Sep 2025

Scientists Uncover Hidden Role of Cas9 in Building Bacterial Immune Memory

When scientists discovered how bacteria protect themselves against viral invaders, called phages, in the early 2000s, little did they know they'd stumbled upon a revolutionary tool researchers could use to edit the DNA of living cells.

4 Sep 2025

Automated 3D Imaging Uncovers Genetic Markers for Sorghum Leaf Arrangement

By reconstructing 366 sorghum plants from calibrated images, the team showed that automated measurements achieved near-human repeatability and enabled genome-wide association studies (GWAS) to uncover genetic markers linked to leaf orientation.

3 Sep 2025

Tackling KRAS Mutations Unlocks New Hope for Pancreatic Cancer Patients

Accounting for nearly 90% of all pancreatic cancers, pancreatic ductal adenocarcinoma (PDAC) has a five-year survival rate of just 13%. Late-stage diagnosis, limited surgical options, and toxic chemotherapy regimens contribute to its poor outcomes.

2 Sep 2025

First Identification of KPC-Producing Bacteria in Chilean Urban Wastewater

A team of Chilean researchers has identified, for the first time in the country, the presence of KPC-type carbapenemase-producing bacteria in wastewater samples from the Greater Concepción Metropolitan Area.

2 Sep 2025

Genetic On-Off Switch for Cilia Formation Uncovered

Some might say it looks like a finger. Others might see a worm. Scientists in the field often liken it to an antenna. The technical name is primary cilium.

2 Sep 2025

Mathematical Approach Restores Altered Cellular Responses to Normal States

Previously, research on controlling gene networks has been carried out based on a single stimulus-response of cells.

2 Sep 2025

Plants Activate Immunity Instead of Growth During Drought Recovery

A plant's number one priority is to grow-a feat that demands sunlight, nutrients, and water. If just one of these three inputs is missing, like water in a drought, growth halts.

2 Sep 2025

Scientists Discover New Microbial Metabolism That Breathes Iron Minerals

An international team of scientists led by microbiologists Marc Mussmann and Alexander Loy from the University of Vienna has discovered a new microbial metabolism: so-called MISO bacteria "breathe" iron minerals by oxidizing toxic sulfide.

28 Aug 2025

New "DNA Organizer" Found to Be Essential for Sperm Stem Cell Development

A research team at Kyoto University has discovered STAG3-cohesin, a new mitotic cohesin complex that helps establish the unique DNA architecture of spermaotogonial stem cells (SSCs), the stem cells that give rise to sperm.

27 Aug 2025

New Imaging Method Reveals Lipid Distribution in Tiny Worms with High Precision

Understanding how fat molecules are distributed and function in living organisms is key to uncovering mechanisms of aging, disease, and metabolism.

25 Aug 2025

Scientists Use Single-Cell Proteomics to Track Blood Cell Differentiation

In the past decade there has been significant interest in studying the expression of our genetic code down to the level of single cells, to identify the functions and activities of any cell through the course of health or disease.

25 Aug 2025

Comprehensive Guide Sets New Standards for Plant Fluorescence Imaging

A team of expert scientists led by Kirk Czymmek, PhD, director of the Advanced Bioimaging Laboratory at the Donald Danforth Plant Science Center and Heather E. McFarlane, assistant professor at the University of Toronto and collaborators from the Danforth Center, University of Leeds (UK), University of Massachusetts (Amherst), University of California - Davis, University of Naples Federico II, University of Minnesota and Université de Montréal, have authored a comprehensive guide to elevate the quality, transparency, and reproducibility of fluorescence microscopy in plant research. The guide was recently published in the journal Plant Cell, "Best Practices in Plant Fluorescence Imaging and Reporting: A Primer"

22 Aug 2025