Malignant News and Research

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Cryo-ET Reveals Native Membrane Architecture of Synchronous RyR1 Calcium Channels

Using cryo-electron microscopy, researchers at the Max Delbrück Center have revealed how muscle cell calcium channels open synchronously. The findings, published in "Nature Communications," may explain a mechanism behind serious muscle diseases.

25 Sep 2026

Mitochondrial RNA May Explain How Tumors Become Resistant to Immunotherapy

Research highlights mitochondrial RNA's influence on interferon signaling, linking chronic exposure to tumor growth and offering new avenues for immunotherapy.

22 Sep 2026

Reprogramming Tumor Immune Microenvironment to Combat Aggressive Glioblastoma Brain Cancer

Mayo Clinic researchers have identified a potential new approach to treating glioblastoma that could help the immune system fight the aggressive brain cancer while improving the effectiveness of existing chemotherapy.

11 Sep 2026

Study Reveals Structural Roughness as Key Factor in Tumor Detachment Dynamics

In 2024, malignant tumors caused more than 21,300 deaths in Austria, 4.7% more than in 2014. Faced with a similarly pressing global challenge, scientists are striving to better understand what drives cancer cells to grow, spread, and invade healthy tissue.

10 Sep 2026

Engineering Stem-Cell-Derived Immune Cells to Teach T Cells to Fight Cancer

The human body contains vast numbers of T cells capable of seeking out and eliminating malignancies if they were properly activated. Currently, a group from UC San Francisco has developed a technique to achieve this by merging laboratory-cultivated immune cells with samples from a person's malignancy.

26 Aug 2026

New Potential Target for Triple-Negative Breast Cancer

The study uncovers how macrophages recruit nerves in triple-negative breast cancer, suggesting BDNF signaling as a critical factor in tumor progression.

18 Aug 2026

Newly Identified Protein Prevents T Cells From Destroying Cancer Cells

Researchers at Mayo Clinic have identified a protein that cancer cells use to suppress the body's immune response, a finding that could support the development of new treatments to improve the effectiveness of cancer immunotherapies.

5 Aug 2026

T Cells Identify Dangerous Pathogenic Threats to Keep Bodies Healthy

Your body depends on T cells to stay healthy. These white blood cells act like a neighborhood watch in the body, helping the immune system spot threats such as viruses, bacteria, and cancer cells.

3 Aug 2026

Advanced Synthetic Bone Graft Fights Infections and Kills Cancer Cells

Primary bone tumors, such as osteosarcoma, have seen stagnant survival rates over the past four decades.

10 Jul 2026

Peking University Researchers Map High Dimensional Cellular Networks in Tumors

A comprehensive review led by Associate Researcher Linnan Zhu and Academician Zemin Zhang at Biomedical Pioneering Innovation Center (BIOPIC), Peking University, China, and Chongqing Medical University, China, was published in Volume 2, article number 27 of the journal Immunity & Inflammation on June 05, 2026.

13 Jun 2026

New Cell Therapy Modifies Natural Killer Cells Against Cancer

Scientists have made great progress in harnessing the body's own immune cells to treat so-called liquid tumors, cancers of the blood and lymphatic system.

11 Jun 2026

Researchers Outline Dynamic Protein Control Systems for Better Clinical Decisions

Cancer has often been explained through mutations in deoxyribonucleic acid (DNA) or changes in ribonucleic acid (RNA), but these layers do not fully explain why tumors with similar genetic profiles can behave differently.

10 Jun 2026

Researchers Discover That Lesion Cells Fail to Recruit Surrounding Tissue Into Tumor Growth Helpers

In an unexpected finding, a new study flips on its head researchers' understanding of how precancerous pancreas lesions evolve into pancreatic cancer. The paradigm-changing discovery has tremendous implications for identifying people at higher risk of cancer or even, potentially stopping malignant transformation.

21 May 2026

Novel Immunotherapy Disrupts the Protective Tumor Microenvironment Ecosystem

Chimeric antigen receptor T-cell therapy - CAR T for short - has been a major advance in treating blood cancers like leukemia and lymphoma. But the immunotherapy has struggled against solid tumors for two main reasons: tumor cells often don't share one consistent surface target, and many solid tumors are protected by a dense network of scar tissue and immune-suppressive cells that blocks T cells.

31 Mar 2026