Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Biognosys Launches Next-Generation Blood Biomarker Discovery Solution

Biognosys today announces the launch of its next-generation blood biomarker discovery solution, which will be offered as a contract research service.

From Biognosys 10 Nov 2021

CN Bio and iiCON announce COVID-19 research collaboration

CN Bio, a leading Organ-on-a-chip Company (OOC) that designs and manufactures single- and multi-organ microphysiological systems (MPS), today announced a research collaboration with the Infection Innovation Consortium (iiCON), a global collaborative infectious disease R&D programme, to validate the next generation of COVID-19 research tools.

From CN Bio Innovations Limited 9 Nov 2021

bit.bio raises in excess of $100 million in first close of Series B financing

Today bit.bio announces the first close of their Series B financing of $103 million.

From bit.bio 6 Nov 2021

ioSkeletal Myocytes | New product launch

bit.bio has today launched a new product, ioSkeletal Myocytes.

From bit.bio 27 Oct 2021

bit.bio expands Board of Directors with appointment of entrepreneurs and Nobel Laureate

Today bit.bio welcomed three new members to its Board of Directors, who bring their respective experience of turning world-class science into new industries.

From bit.bio 27 Oct 2021

Study identifies highly potent monoclonal antibody against all SARS-CoV-2 variants

Researchers identified a greatly potent monoclonal antibody that aims at the spike protein of SARS-CoV-2.

19 Oct 2021

Virginia Tech scientists receive $1 million grant to predict the mechanics of living cells

With advances in deep learning, machines are now able to "predict" a variety of aspects about life, including the way people interact on online platforms or the way they behave in physical environments.

15 Oct 2021

New datasets published to better train ML models for drug discovery

Polymorphs are molecules that have different molecular packing arrangements despite identical chemical compositions. In a recent paper, researchers at GlaxoSmithKline (GSK) and the Cambridge Crystallographic Data Centre (CCDC) combined their proprietary (GSK) and published (CCDC) datasets to better train machine learning (ML) models to predict stable polymorphs to use in new drug candidates.

4 Oct 2021

Experts unravel inner workings of cell receptors involved in various diseases

Scientists revealed the operational mechanism of possible drug targets for numerous diseases like rheumatoid arthritis, cancer, and even COVID-19.

1 Oct 2021

Scientists develop lung organoids to imitate actual SARS-CoV-2 infection

The emergence of the COVID-19 pandemic in the United States in early 2020 left researchers struggling to identify lab models of SARS-CoV-2 infection.

From UC San Diego 2 Sep 2021

Study discovers actionable DNA errors remain stable over time

A single analysis of the entire tumor DNA is mostly sufficient to identify all DNA errors that might be relevant for treating metastatic cancer.

11 Aug 2021

Graphene covered with bactericidal molecules inhibits harmful biofilm formation

Bacterial infections associated with medical implants place a major burden on healthcare and cause great suffering to patients across the world.

11 Aug 2021

Researchers create new drug database to facilitate repurposing of drugs

Scientists developed a new open-access database with information on drug candidates and the process of metabolization of the drugs by the body.

5 Aug 2021

Study explores the effectiveness of a natural protein against colon cancer cells

Scientists and faculty of Vanderbilt University are in search of the “Achilles’ heel” of cancer cells that survive initial chemotherapy.

From Vanderbilt University 5 Aug 2021

Medicines Discovery Catapult relaunches Wolfson Radiochemistry facility in Manchester

Medicines Discovery Catapult (MDC) today announces the relaunch of radiochemistry at the Wolfson Molecular Imaging Centre (WMIC) in Manchester.

5 Aug 2021

Study highlights novel approach for designing anti-viral drugs

Scientists are exploring a novel screening approach that concentrates on the recognition of virus-specific morphological changes in virus-infected cells.

4 Aug 2021

Next generation automation lab achieves huge productivity gains

Eli Lilly and Company and their industry partners, including sample management specialists – Ziath, are speeding the discovery of new medicines through the fully automated Lilly Life Sciences Studio lab in San Diego, USA.

From Ziath Ltd 30 Jul 2021

Researchers develop a cost-effective and versatile approach for drug synthesis

Different factors influence the cost-effectiveness of drug synthesis, the amount of waste generated being one of those.

29 Jul 2021

Already characterized active substances exhibit unexpected effects

Every innovative drug starts with the search for an active substance targeting key players in disease-related processes.

23 Jul 2021

Study identifies many small molecules that bind to certain areas of the SARS-CoV-2 genome

Scientists at Goethe University have now identified some regions of the SARS-CoV-2 genome that might be an ideal target for future drugs.

21 Jul 2021