Mass Spectrometry News and Research

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Mass spectrometry is an analytical method used to identify different compounds based on the atomic sample constitution of the molecules and their charge state, which enables “blind” analysis of an unknown sample without any prior knowledge of its composition.

Study reveals new therapeutic targets on SARS-CoV-2 Spike protein

Considering the recent COVID-19 pandemic, significant investigations are being made to find out how the SARS-CoV-2 Spike protein binds to a human cell.

23 Feb 2021

Study provides insight into the structure of prion proteins responsible for diseases

Prion diseases are a group of rapidly progressive, fatal and infectious neurodegenerative disorders affecting both humans and animals: Bovine Spongiform Encephalopathy (BSE) or 'mad cow' disease is one of the most famous since in 1996 scientists found that the agent responsible for the disease in cows, is the same agent responsible for the so-called variant Creutzfeldt-Jakob Disease (vCJD), a disease affecting humans.

22 Feb 2021

New gel electrophoresis method allows rapid diagnosis of biomarkers by mass spectrometry

Polyacrylamide gel electrophoresis is a technique that allows high-resolution isolation of proteins separated from biological specimens.

22 Feb 2021

New technique reveals natural structure of large enzyme complex

A new technique has revealed the natural structure of specifically massive and complex enzymes.

11 Feb 2021

Researchers explore the regulatory role of protein in human health and disease

Researchers from the University of Virginia, Lehigh University and the Massachusetts Institute of Technology are pooling their respective labs' expertise to unlock the mysteries of a protein that plays a critical regulatory role in human health and disease.

5 Feb 2021

Juicing technique can influence phytochemical content, antioxidant activity of vegetable juices

With the New Year, many people are making resolutions to eat healthier, by eating more vegetables, for example. But those who don't like the taste or texture of some vegetables might prefer to drink them in a home-squeezed juice.

28 Jan 2021

Unique proteomics-based technology can help diagnose breast cancer more accurately

Breast cancer could be identified more precisely than existing methods using blood specimens and exclusive proteomics-based technology.

28 Jan 2021

Using mass spectrometry to determine the sex of fingermarks

In this interview, AZoLifeSciences speaks to Prof. Simona Francese about her latest research into fingermarks and how, by using MALDI-MS, you can accurately determine their sex.

15 Jan 2021

Using proteomics to determine how long a corpse has been underwater

In this interview, AZoLifeSciences speaks to Dr. Noemi Procopio about her latest research which involved using bone proteomics to determine the length of time a corpse had been left underwater.

11 Jan 2021

New technique to detect gene doping in human plasma

All athletes wish to be at the top of their game while competing, yet some turn to corrupt strategies to achieve peak speed, agility, and muscle growth. Latest advancements in gene editing technology could lure athletes to change their DNA to gain an upper hand.

7 Jan 2021

Study addresses mystery of how chromosomes are inherited during cell division

Starting as a single cell, organisms undergo millions of generations of divisions to ultimately generate the bones, heart, brain and other components that make up a living being. The mainspring within this intricate process is the transfer of DNA through each subsequent cell split within discrete packets called chromosomes.

7 Jan 2021

Altered sugar composition impacts cell-to-surface adhesion

Biotechnologists measure the forces with which algae cells adhere to surfaces and move on them. How can cells adhere to surfaces and move on them? This is a question that was investigated by an international team of researchers headed by Prof. Michael Hippler from the University of Münster and Prof. Kaiyao Huang from the Institute of Hydrobiology (Chinese Academy of Sciences, Wuhan, China).

4 Jan 2021

Subspace mass spectrometry imaging method can accelerate speed of data acquisition

A new computational mass spectrometry imaging method enables researchers to achieve high mass resolution and high spatial resolution for biological samples while providing data sets exponentially faster.

11 Dec 2020

Neuropeptides produced by cockroaches could someday be targeted by new pesticides

Cockroaches are notorious for their abilities to survive and reproduce, much to humanity's chagrin. In addition to scurrying around at night, feeding on human and pet food, and generating an offensive odor, the pests can transmit pathogens and cause allergic reactions.

10 Dec 2020

Researchers use new decoding method to identify novel proteins encoded by HSV-1

Comprehensive identification of viral proteins encoded by viral genes is required to understand the pathophysiology of viral infections.

8 Dec 2020

Scientists use advanced methods for investigating structure and interactions of proteins

Michael Gross, professor of chemistry in Arts & Sciences at Washington University in St. Louis and of immunology and internal medicine at the School of Medicine, and his team are experts in footprinting proteins -- that is, using advanced methods for investigating the structure and interactions of proteins within larger molecules.

8 Dec 2020

Disturbances in the gut microbiome may explain major depressive disorder

Researchers have successfully detected three bacteriophages, 50 fecal metabolites, 47 bacterial species that were considerably more or less abundant in patients with major depressive disorder (MDD) when compared to healthy controls. The study involved 311 individuals.

4 Dec 2020

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