Life Science Articles

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Ghost Cytometry - Revolutionizing Cell Sorting

Complex, heterogenous systems such as those in immunology, neuroscience, and development can be better understood by studying their associated cellular characteristics. This field has been called “cytometry”.

14 Feb 2020

How to Reduce Background Noise in IHC

IHC is a very effective way of studying tissue architecture. This article outlines common problems in IHC and explains how to solve these issues.

14 Feb 2020

Telomere Shortening and Stress

Living with chronic stress can lead to many reported health effects, such as decreased cardiovascular function and reduced immune system efficiency.

14 Feb 2020

Life Science Applications of the Top-Down Approach

Applying the top-down approach to the life sciences has contributed to the development of new methodologies for protein analysis, providing a greater understanding of the proteoform within its natural context.

14 Feb 2020

What is Phosphoproteomics?

Phosphoproteomics is a specific type of proteomics that characterizes proteins with the reversible post-translational modification of phosphorylation.

14 Feb 2020

What are CAR T cells?

CAR T cells are T lymphocytes that have been genetically engineered to express a chimeric antigen receptor that is specific to a tumor antigen.

14 Feb 2020

How is Chemoinformatics Used in Drug Discovery?

Chemoinformatics is based upon the computational analysis of data concerning chemical and molecular structures.

14 Feb 2020

Best Practices for Cannabis Cultivation: A Meta-Analysis

A meta-analysis of cannabis yields reports that plant density, light intensity, and fertilization are the major contributors to cannabis yield.

14 Feb 2020

Using Yeast to Produce Novel Cannabinoid Analogs

Scientists have manipulated the gene expression of the yeast Saccharomyces cerevisiae, t produce both standard cannabinoids and novel analogs.

14 Feb 2020

Spatial Gradients in Cannabis and Concerns for Medical Use

Researchers have uncovered how cannabinoid profiles that vary within the same Cannabis plant can elicit organ-specific effects in the plant itself.

14 Feb 2020

Gene Knockout Method

The methods used to carry out gene knockout are mutation, RNAi gene silencing, conditional knockout using Cre recombinase and gene editing using CRISPR.

14 Feb 2020

Applications of Conditional Gene Knockout Technology

This article describes the process of conditional gene knockout technology, including Cre-LoxP and CRISPR-Cas9, and its applications in research.

14 Feb 2020

Interpreting Proteomics Data

Proteomics is the large-scale study of proteomes, exploring a range of protein activities including expression, movement, and interaction.

14 Feb 2020

Compound Identification for Nontargeted Metabolomics

In an untargeted metabolomic approach, thousands of metabolites are studied in one sample; however, the chemical identity of the compound is not known as in the targeted approach.

14 Feb 2020

GPCR Signaling Pathways

This article describes the proteins involved in signaling through G protein coupled receptors (GPCRs) and their associated G protein subunits.

14 Feb 2020

What is 3D X-Ray Microscopy?

3D X-ray microscopy is a non-destructive imaging technique that provides 3D visualization of internal microstructures in biological samples at sub-micron to nanoscale spatial resolution.

14 Feb 2020

TEM Imaging Modes

Over the years, the electron microscope has been improved upon, with a wide array of TEM imaging modes now available for use.

14 Feb 2020

Imaging Nuclear Structures Using AFM

Atomic force microscopy builds 3D images of nuclear structures by raster scanning the sample and reading height differences.

14 Feb 2020

Artificial Tissue Implants: Understanding Cell Adhesion to Polymeric Substances

Understanding the adhesion of epithelial cells to different biodegradable, 3D printable polymers is vital for developing new artificial tissue implants.

14 Feb 2020