Biochemistry

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Liver fibrosis might be treatable with selective immunotoxins

Chronic alcohol abuse and hepatitis can injure the liver and lead to fibrosis, the buildup of collagen and scar tissue. As a potential approach to treating liver fibrosis, University of California San Diego School of Medicine researchers and their collaborators are looking for ways to stop liver cells from producing collagen.

13 Jul 2021

Researchers establish efficient genetic engineering platform in Pichia pastoris

Pichia pastoris is a model methylotrophic yeast that can easily realize high-density fermentation.

13 Jul 2021

Researchers identify gene responsible for vicine-convicine content in faba beans

Faba beans are exceptional sources of food protein; however, around 4 % of the world’s population is affected by favism.

12 Jul 2021

New genetic technique shows the relationship between thyroid function and lipid profile

The thyroid gland produces amino acid-based compounds known as thyroid hormones.

12 Jul 2021

Researchers develop novel technique to control tiny water droplets in lab-on-a-chip applications

Scientists develop a method to better manipulate tiny droplets in lab-on-a-chip applications for biochemistry, cell culturing, and drug screening.

12 Jul 2021

New screening method allows identification of drugs that glue proteins together

Scientists developed a new screening method that tests the effectiveness of therapeutic molecules developed to “glue” proteins together in the body.

9 Jul 2021

Emerging variants of COVID-19 could be treated with a new anticoagulant drug

The capacity of the COVID-19 virus’s spikes to bind to human cells may be hampered by molecules from the same family as the anticoagulant medication heparin.

9 Jul 2021

Engineered enzyme facilitates more effective plastic degradation

Plastic was previously considered a manufacturing miracle as it was inexpensive to produce.

9 Jul 2021

Protein's 'silent code' influences cell movement

The protein actin is ubiquitous and essential for life. In mammals, every cell expresses two of its forms, beta-actin and gamma-nonmuscle-actin. Despite having distinct roles, the two forms are nearly identical, sharing 99% of their amino acid sequence.

8 Jul 2021

New protein plays a critical "go, or no-go" role in germination

Dehydrated plant seeds can lay dormant for long periods--over 1,000 years in some species--before the availability of water can trigger germination. This protects the embryonic plant inside from a variety of environmental stresses until conditions are favorable for growth and survival.

8 Jul 2021

Meat and meat-based substitutes vary widely in their nutritional content

Plant-based meats are similar to real beef in their taste, along with the 13 nutritional items listed on their labels making them appear equivalent to meat.

8 Jul 2021

Lipidomics study reveals schizophrenic patients’ resistance to antipsychotic drugs

Scientists discovered 22 lipids in the blood plasma of schizophrenia patients that were linked to slower symptom improvement over time.

8 Jul 2021

Study identifies the gene responsible for toxic vicine and convicine production in faba beans

Faba beans have been a good source of protein. A team of experts has now found the gene that causes the toxic vicine and convicine to be produced.

7 Jul 2021

Researchers uncover cellular mechanisms by which the silencing therapies act in cells

Gene silencing therapies are used to interfere with, or "silence", the expression of genes that are associated with disorders. Now, a team at TMDU has uncovered some of the cellular mechanisms by which the silencing therapies act in cells.

7 Jul 2021

Nanobody mapping using NMR proves a promising alternative for therapeutic use

Researchers used NMR techniques to determine the structure of a nanobody, facilitating a better understanding of how the protein fights against diseases.

6 Jul 2021

New technique to upcycle beer industry waste hops into cellulose nanofibers

A team of Japanese researchers has devised a method for converting discarded hop into cellulose nanofibers (CNFs).

6 Jul 2021

Study reveals novel enzyme vital for the production of bacterial tropone natural products

Microorganisms produce natural products, for example, as disease-causing virulence factors or as defense substances against predators and competitors.

5 Jul 2021

Two new studies reveal the power of microbiome in plants

Hundreds of different bacterial species live in and on leaves and roots of plants. A research team led by Julia Vorholt from the Institute of Microbiology at ETH Zurich, together with colleagues in Germany, first inventoried and categorized these bacteria six years ago.

2 Jul 2021

New approach uses engineered yeast cells to study proteins that regulate gene expression

Researchers have developed a more efficient platform for studying proteins that play a key role in regulating gene expression. The approach uses engineered yeast cells to produce enzyme and histone proteins, conduct biochemical assays internally, and then display the results.

2 Jul 2021

Maya population size varied over time in response to climate change, study shows

A McGill-led study has shown that the size of the Maya population in the lowland city of Itzan (in present-day Guatemala) varied over time in response to climate change. The findings, published recently in Quaternary Science Reviews, show that both droughts and very wet periods led to important population declines.

1 Jul 2021

Biochemistry

Liver fibrosis might be treatable with selective immunotoxins

Researchers establish efficient genetic engineering platform in Pichia pastoris

Researchers identify gene responsible for vicine-convicine content in faba beans

New genetic technique shows the relationship between thyroid function and lipid profile

Researchers develop novel technique to control tiny water droplets in lab-on-a-chip applications

New screening method allows identification of drugs that glue proteins together

Emerging variants of COVID-19 could be treated with a new anticoagulant drug

Engineered enzyme facilitates more effective plastic degradation

Protein's 'silent code' influences cell movement

New protein plays a critical "go, or no-go" role in germination

Meat and meat-based substitutes vary widely in their nutritional content

Lipidomics study reveals schizophrenic patients’ resistance to antipsychotic drugs

Study identifies the gene responsible for toxic vicine and convicine production in faba beans

Researchers uncover cellular mechanisms by which the silencing therapies act in cells

Nanobody mapping using NMR proves a promising alternative for therapeutic use

New technique to upcycle beer industry waste hops into cellulose nanofibers

Study reveals novel enzyme vital for the production of bacterial tropone natural products

Two new studies reveal the power of microbiome in plants

New approach uses engineered yeast cells to study proteins that regulate gene expression

Maya population size varied over time in response to climate change, study shows

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