Genomics

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Next-generation sequencing for minimal residual disease proven more sensitive than flow cytometry

In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive.

2 Dec 2021

Study identifies genes that protect ovarian cancer from antitumor immunity

Immunotherapies are exhibiting better clinical benefit in the treatment of numerous cancers, particularly when used along with chemotherapy.

2 Dec 2021

Novel technique precisely corrects DNA errors in cultured patient cells

Scientists recently created a technique to accurately and quickly correct genetic alterations in the cultivated patient cells.

2 Dec 2021

New CRISPR technology could improve diagnostic tests for COVID-19

A new type of CRISPR platform that leverages the benefits of a compact RNA-editing protein could result in enhanced diagnostic tests for COVID-19.

2 Dec 2021

Study unearths novel mechanism coordinating the assembly of cell components

A group of researchers recently unearthed vital information on how gene expression is orchestrated.

2 Dec 2021

Study analyzes response of individuals from diverse populations to infections

A recent study has identified differences in immune pathway activation to influenza infection between people of European and African genetic ancestry.

2 Dec 2021

Researchers identify new route to produce complex antibiotics

Researchers recently discovered a novel route to produce complex antibiotics taking advantage of gene editing to re-program pathways to future medicines.

From The University of Manchester 2 Dec 2021

Researchers use X-ray from 3rd synchrotron facility to analyze 3D structure of chromosomes

Threads or earphone cables placed in tight spaces get easily tangled. On the contrary, our body's long and loose DNA packs into rod-shaped chromosomes one-millionth its size when the cell divides.

30 Nov 2021

Cornell food scientists develop new tool to quantify zinc status within the body

Zinc deficiency is prevalent around the world, and among children, these mineral shortfalls can lead to stunting, embryonic malformations and neurobehavioral abnormalities.

26 Nov 2021

Using CRISPR/Cas9-based gene editing to produce the ‘perfect’ barley

After a spell of unexpected rain, before the harvest season, a farmer may be faced with the unpredictable problem of untimely sprouting of barley.

26 Nov 2021

New partnership to harness the power of genomic science to overcome poverty, hunger, and malnutrition

A five-year partnership being launched by the Innovative Genomics Institute (IGI) -; a non-profit founded by Nobel Laureate Jennifer Doudna -; and CGIAR, the world's largest publicly-funded agricultural research partnership, will harness the power of science to help millions of people overcome poverty, hunger, and malnutrition.

26 Nov 2021

Cancer data available for global scientists through Microsoft’s Azure

The International Cancer Genome Consortium (ICGC) is further enhancing cancer research globally by constructing a huge collection of cancer data.

25 Nov 2021

Novel platform provides higher level of accuracy in genomic analysis

The Earlham Institute has enhanced its ability in high-fidelity long-read sequencing through a pair of the innovative Pacific Biosciences Sequel IIe platforms.

25 Nov 2021

Regulating the activity of a protein enhances health span, says research

Scientists from KAIST put forth novel insights for enhancing the health span by controlling a protein’s activity.

25 Nov 2021

New technique could dramatically speed up the breeding of new crops

Scientists are a step closer to breeding plants with genes from only one parent. New research led by plant biologists at the University of California, Davis, published Nov. 19 in Science Advances, shows the underlying mechanism behind eliminating half the genome and could make for easier and more rapid breeding of crop plants with desirable traits such as disease resistance.

From The University of California, Davis 22 Nov 2021

Researchers develop artificial genomic DNA capable of replication and evolution

Professor Norikazu Ichihashi and his colleagues at the University of Tokyo have successfully induced gene expression from a DNA, characteristic of all life, and evolution through continuous replication extracellularly using cell-free materials alone, such as nucleic acids and proteins for the first time.

22 Nov 2021

Research identifies genes involved in the production of scorpion venom

A team of international researchers discovered an inventive, animal-friendly means for investigating venom genes.

19 Nov 2021

Study analyzes the risk of re-identification of shared genomic data

Direct-to-consumer genetic testing allowed millions of people to ascertain their ancestry and obtain awareness of their genetic pre-disposition to inherited diseases.

19 Nov 2021

Study elucidates the role of genomics in obsessive-compulsive disorder

According to recent research carried out by the researchers from the Icahn School of Medicine at Mount Sinai, both rare and commonly seen differences in the DNA letters threaded along an individual’s chromosomes can elucidate about a third of the risk for being diagnosed with obsessive-compulsive disorder (OCD).

19 Nov 2021

Study identifies new variants for polycystic ovary syndrome

Scientists from the Institute of Genomics of the University of Tartu recently identified the association between polycystic ovary syndrome and genetics.

19 Nov 2021